Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sophie Lenoir"'
Autor:
Matthieu Lépine, Sara Douceau, Gabrielle Devienne, Paul Prunotto, Sophie Lenoir, Caroline Regnauld, Elsa Pouettre, Juliette Piquet, Laurent Lebouvier, Yannick Hommet, Eric Maubert, Véronique Agin, Bertrand Lambolez, Bruno Cauli, Carine Ali, Denis Vivien
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Perineuronal nets (PNNs) are specialized extracellular matrix structures mainly found around fast-spiking parvalbumin (FS-PV) interneurons. In the adult, their degradation alters FS-PV-driven functions, such as brain plasticity an
Externí odkaz:
https://doaj.org/article/c11000b8633744f48ebb73d794a305b9
Autor:
Sophie Lenoir, Romane A. Lahaye, Hélène Vitet, Chiara Scaramuzzino, Amandine Virlogeux, Laetitia Capellano, Aurélie Genoux, Noga Gershoni-Emek, Michal Geva, Michael R. Hayden, Frédéric Saudou
Publikováno v:
Neurobiology of Disease, Vol 173, Iss , Pp 105857- (2022)
Huntington disease (HD) is a neurodegenerative disorder caused by polyglutamine-encoding CAG repeat expansion in the huntingtin (HTT) gene. HTT is involved in the axonal transport of vesicles containing brain-derived neurotrophic factor (BDNF). In HD
Externí odkaz:
https://doaj.org/article/fd15b7293989424cb83b9058a66155a8
Autor:
Hyeongju Kim, Sophie Lenoir, Angela Helfricht, Taeyang Jung, Zhana K. Karneva, Yejin Lee, Wouter Beumer, Geert B. van der Horst, Herma Anthonijsz, Levi C.M. Buil, Frits van der Ham, Gerard J. Platenburg, Pasi Purhonen, Hans Hebert, Sandrine Humbert, Frédéric Saudou, Pontus Klein, Ji-Joon Song
Publikováno v:
JCI Insight, Vol 7, Iss 17 (2022)
Huntington’s disease (HD) is a late-onset neurological disorder for which therapeutics are not available. Its key pathological mechanism involves the proteolysis of polyglutamine-expanded (polyQ-expanded) mutant huntingtin (mHTT), which generates N
Externí odkaz:
https://doaj.org/article/4386a98caf404dd9a84e53f674710b00
Autor:
Hélène Party, Cléo Dujarrier, Marie Hébert, Sophie Lenoir, Sara Martinez de Lizarrondo, Raphaël Delépée, Claudine Fauchon, Marie-Christine Bouton, Pauline Obiang, Olivier Godefroy, Etienne Save, Laurent Lecardeur, Joëlle Chabry, Denis Vivien, Véronique Agin
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Major depressive disorder (MDD) is one of the most frequent psychiatric illnesses, leading to reduced quality of life, ability to work and sociability, thus ranking among the major causes of disability and morbidity worldwide. To date, genet
Externí odkaz:
https://doaj.org/article/f491f63c017d42d194af67d6b4583770
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100382- (2021)
Summary: BDNF levels are reduced in the chronically stressed brain, in the area of hippocampus. Part of the hippocampal BDNF is provided by neuronal projection of the entorhinal cortex. Studying the cortico-hippocampal transport of BDNF in vivo is te
Externí odkaz:
https://doaj.org/article/3c31f6cd5709418db5f937e5eeb931e1
Autor:
Sophie Lenoir, Alexandre Varangot, Laurent Lebouvier, Thierry Galli, Yannick Hommet, Denis Vivien
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The neuronal serine protease tissue-type Plasminogen Activator (tPA) is an important player of the neuronal survival and of the synaptic plasticity. Thus, a better understanding the mechanisms regulating the neuronal trafficking of tPA is required to
Externí odkaz:
https://doaj.org/article/4320c44fa0e744c8ab01cf323c88f93f
Autor:
Laurent Cotter, Romane A Lahaye, Wei Chou Tseng, Yuanjing Liu, Aude Lemesle, Sophie Lenoir, Elena Dale, Frédéric Saudou, Anselme L Perrier
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c107d2ed5bf689f39d5b345acb1e302f
https://doi.org/10.1136/jnnp-2022-ehdn.233
https://doi.org/10.1136/jnnp-2022-ehdn.233
Autor:
Michal Geva, Chiara Scaramuzzino, Sophie Lenoir, Romane A Lahaye, Shao-Ming Wang, Hsiang-en Wu, Noga Gershoni-Emek, Frédéric Saudou, Tsung-Ping Su, Michael R Hayden
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b65784aba1eb66b2710cc71acdb8e82
https://doi.org/10.1136/jnnp-2022-ehdn.249
https://doi.org/10.1136/jnnp-2022-ehdn.249
Autor:
Sophie Lenoir, Romane A. Lahaye, Hélène Vitet, Chiara Scaramuzzino, Amandine Virlogeux, Laetitia Capellano, Aurélie Genoux, Noga Gershoni-Emek, Michal Geva, Michael R. Hayden, Frédéric Saudou
Publikováno v:
Neurobiology of disease. 173
Huntington disease (HD) is a neurodegenerative disorder caused by polyglutamine-encoding CAG repeat expansion in the huntingtin (HTT) gene. HTT is involved in the axonal transport of vesicles containing brain-derived neurotrophic factor (BDNF). In HD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2ca6386b12235107df1575831d23fc
https://pubmed.ncbi.nlm.nih.gov/36075537
https://pubmed.ncbi.nlm.nih.gov/36075537
Autor:
Maria-Victoria Hinckelmann, Frédéric Saudou, Morgane Louessard, Rémi Carpentier, Sophie Lenoir, Patricia Lino, Aurélie Genoux, Sandrine Humbert, Laura Auboyer, Anselm Perrier, Chiara Scaramuzzino, Amandine Virlogeux
Publikováno v:
I: Experimental therapeutics – preclinical.
Background Huntington Disease (HD) involves a complex cascade of pathogenic events, but central to its disruption of the cortico-striatal circuitry is impaired trafficking of Brain-Derived Neurotrophic Factor (BDNF). Aim We hypothesized that improvin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::639ab5cc70461b946f0608deb119d86f
https://doi.org/10.1136/jnnp-2021-ehdn.119
https://doi.org/10.1136/jnnp-2021-ehdn.119