Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sophie Layalle"'
Autor:
Sophie Layalle, Franck Aimond, Véronique Brugioti, Claire Guissart, Cédric Raoul, Laurent Soustelle
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a devastating paralytic disorder caused by the death of motoneurons. Several mutations in the KIF5A gene have been identified in patients with ALS. Some mutations affect the splicing sites of exon 27 le
Externí odkaz:
https://doaj.org/article/b0fbda0c71d844aea463901fe3f792da
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 904 (2021)
Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disease characterized by the progressive degeneration of upper and lower motoneurons. Most ALS cases are sporadic but approximately 10% of ALS cases are due to inherit
Externí odkaz:
https://doaj.org/article/dc526b882d034a67b803086a1df43098
Autor:
Marine Pons, Claire Soulard, Laurent Soustelle, Marie-Laure Parmentier, Yves Grau, Sophie Layalle
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The function of the nervous system in complex animals is reflected by the achievement of specific behaviors. For years in Drosophila, both simple and complex behaviors have been studied and their genetic bases have emerged. The neuromuscular junction
Externí odkaz:
https://doaj.org/article/de556c5ef9ff4f1d9f2845b8dfa018df
Autor:
Yoan Arribat, Nathalie Bonneaud, Yasmina Talmat-Amar, Sophie Layalle, Marie-Laure Parmentier, Florence Maschat
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68775 (2013)
Huntington's disease (HD) is caused by the abnormal expansion of the polyglutamine tract in the human Huntingtin protein (polyQ-hHtt). Although this mutation behaves dominantly, huntingtin loss of function also contributes to HD pathogenesis. Indeed,
Externí odkaz:
https://doaj.org/article/b2b0f85b48c64af7a4ca894c83704d40
Control of nerve cord formation by Engrailed and Gooseberry-Neuro: A multi-step, coordinated process
Autor:
Christelle Dantec, Sophie Layalle, Dany Severac, Alain Ghysen, Florence Maschat, Nathalie Bonneaud, Sophie Colomb, Nicolas Nègre, Christophe Jourdan
Publikováno v:
Developmental Biology
Developmental Biology, Elsevier, 2017, 432 (2), pp.273-285. ⟨10.1016/j.ydbio.2017.10.018⟩
Developmental Biology, Elsevier, 2017, 432 (2), pp.273-285. ⟨10.1016/j.ydbio.2017.10.018⟩
One way to better understand the molecular mechanisms involved in the construction of a nervous system is to identify the downstream effectors of major regulatory proteins. We previously showed that Engrailed (EN) and Gooseberry-Neuro (GsbN) transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13daf592ae9d8c9a434a3d7be127c75a
https://hal.archives-ouvertes.fr/hal-01918046
https://hal.archives-ouvertes.fr/hal-01918046
Publikováno v:
Developmental Cell
Developmental Cell, Elsevier, 2008, 15 (4), pp.568-77. ⟨10.1016/j.devcel.2008.08.003⟩
Developmental Cell, Elsevier, 2008, 15 (4), pp.568-77. ⟨10.1016/j.devcel.2008.08.003⟩
International audience; In many metazoans, final adult size depends on the growth rate and the duration of the growth period, two parameters influenced by nutritional cues. We demonstrate that, in Drosophila, nutrition modifies the timing of developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9d6be3c7f72d3677f3c7260bd893cd
https://doi.org/10.1016/j.devcel.2008.08.003
https://doi.org/10.1016/j.devcel.2008.08.003
Autor:
May Ma, Mickael Ohanna, Maija Slaidina, Charles Géminard, Julien Colombani, Marc Bourouis, Marianne Bjordal, Pierre Léopold, Renald Delanoue, Nathalie Arquier, Sophie Layalle
Publikováno v:
Diabetes
Diabetes, American Diabetes Association, 2006, 55 (Supplement 2), pp.S5-S8. ⟨10.2337/db06-S001⟩
Diabetes, 2006, 55 (Supplement 2), pp.S5-S8. ⟨10.2337/db06-S001⟩
Diabetes, American Diabetes Association, 2006, 55 (Supplement 2), pp.S5-S8. ⟨10.2337/db06-S001⟩
Diabetes, 2006, 55 (Supplement 2), pp.S5-S8. ⟨10.2337/db06-S001⟩
Insulin signaling is a conserved feature in all metazoans. It evolved with the appearance of multicellularity, allowing primordial metazoans to respond to a greater diversity of environmental signals. The insulin signaling pathway is highly conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0441312110067b62f531e6812d434dae
https://doi.org/10.2337/db06-s001
https://doi.org/10.2337/db06-s001
Publikováno v:
Genes to Cells. 10:119-125
We identified the gene smooth (sm) in a screen for genes that are specifically expressed within the lineage that forms the adult chemosensory bristles. sm is expressed in most or all differentiating neurones during embryogenesis, but is specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800e137f3191a8246fba954933d594cd
https://doi.org/10.1111/j.1365-2443.2005.00822.x
https://doi.org/10.1111/j.1365-2443.2005.00822.x
Publikováno v:
genesis. 39:246-255
Summary: In Drosophila, the sensory organs are formed by cells that derive from a precursor cell through a fixed lineage. One exception to this rule is the bract cell that accompanies some of the adult bristles. The bract cell is derived from the sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf55a557663b553e716fca499fc8468
https://doi.org/10.1002/gene.20052
https://doi.org/10.1002/gene.20052
Publikováno v:
médecine/sciences. 22:241-243
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cc27fa628dddfe513b87175cd7d8c9
https://doi.org/10.1051/medsci/2006223241
https://doi.org/10.1051/medsci/2006223241