Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Sophie Laguesse"'
Autor:
Aviel Even, Giovanni Morelli, Silvia Turchetto, Michal Shilian, Romain Le Bail, Sophie Laguesse, Nathalie Krusy, Ariel Brisker, Alexander Brandis, Shani Inbar, Alain Chariot, Frédéric Saudou, Paula Dietrich, Ioannis Dragatsis, Bert Brone, Loïc Broix, Jean-Michel Rigo, Miguel Weil, Laurent Nguyen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Microtubule tracks are important for the transport of molecules within axons. Here, the authors show that ATAT1, the enzyme responsible for acetylating a-tubulin, receives acetyl groups from ATP citrate lyase whose stability is regulated by Elongator
Externí odkaz:
https://doaj.org/article/56060abcde1a4c4f802c73b700424575
Autor:
Aviel Even, Giovanni Morelli, Silvia Turchetto, Michal Shilian, Romain Le Bail, Sophie Laguesse, Nathalie Krusy, Ariel Brisker, Alexander Brandis, Shani Inbar, Alain Chariot, Frédéric Saudou, Paula Dietrich, Ioannis Dragatsis, Bert Brone, Loïc Broix, Jean-Michel Rigo, Miguel Weil, Laurent Nguyen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/79e79303396a442f8f0694398022f331
Publikováno v:
Alcohol. 109:73
Autor:
Sophie Laguesse, Laurent Nguyen, Pierre Close, Laura Van Hees, Alain Chariot, Brigitte Malgrange
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The Elongator complex is required for proper development of the cerebral cortex. Interfering with its activity in vivo delays the migration of postmitotic projection neurons, at least through a defective α-tubulin acetylation. However, this complex
Externí odkaz:
https://doaj.org/article/76be2ba8139b4b76814688bec580c824
Autor:
Marie-Laure Volvert, Pierre-Paul Prévot, Pierre Close, Sophie Laguesse, Sophie Pirotte, James Hemphill, Florence Rogister, Nathalie Kruzy, Rosalie Sacheli, Gustave Moonen, Alexander Deiters, Matthias Merkenschlager, Alain Chariot, Brigitte Malgrange, Juliette D. Godin, Laurent Nguyen
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1168-1183 (2014)
The migration of cortical projection neurons is a multistep process characterized by dynamic cell shape remodeling. The molecular basis of these changes remains elusive, and the present work describes how microRNAs (miRNAs) control neuronal polarizat
Externí odkaz:
https://doaj.org/article/f95d433ec4004531bfdcaf3c545b234e
Autor:
David Darevesky, Ellanor L. Whiteley, Sophie Laguesse, Dorit Ron, Anthony L. Berger, Yann Ehinger, Marie Lordkipanidzé, Khanhky Phamluong, Samuel A. Sakhai, Jeffrey J. Moffat, Mélanie Welman, Mehdi Farokhnia, Lorenzo Leggio
Publikováno v:
Addict Biol
Heavy alcohol use reduces the levels of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex of rodents through the upregulation of microRNAs (miRs) targeting BDNF mRNA. In humans, an inverse correlation exists between circulating bl
Autor:
Anthony L. Berger, Sophie Laguesse, Mélanie Welman, Samuel A. Sakhai, Marie Lordkipanidzé, Mehdi Farokhnia, Dorit Ron, Ellanor L. Whiteley, Khanhky Phamluong, Lorenzo Leggio, Jeffrey J. Moffat, David Darevesky, Yann Ehinger
Heavy alcohol use reduces the levels of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex of rodents through the upregulation of microRNAs targetingBDNFmRNA. In humans, an inverse correlation exists between circulating blood level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611aab1fe7ea9c3bf1b0a5381192e4d4
https://doi.org/10.1101/2019.12.18.881680
https://doi.org/10.1101/2019.12.18.881680
Autor:
Anthony L. Berger, Sophie Laguesse, Khanhky Phuamluong, Jong Hyun Park, Dorit Ron, Sami Ben Hamida, Ki Duk Park, Nadege Morisot
Publikováno v:
Addiction Biology. 24:908-920
Alcohol use disorder is a chronic relapsing disease. Maintaining abstinence represents a major challenge for alcohol-dependent patients. Yet the molecular underpinnings of alcohol relapse remain poorly understood. In the present study, we investigate
Autor:
Alexander Brandis, Miguel Weil, Nathalie Krusy, Alain Chariot, Paula Dietrich, Giovanni Morelli, Ariel Brisker, Michal Shilian, Aviel Even, Loïc Broix, Shani Inbar, Silvia Turchetto, Sophie Laguesse, Ioannis Dragatsis, Frédéric Saudou, Romain Le Bail, Jean-Michel Rigo, Bert Brône, Laurent Nguyen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications
Nature Communications
Publikováno v:
Addiction Biology. 22:1856-1869
We previously reported that the kinase AKT is activated in the nucleus accumbens (NAc) of rodents in response to excessive consumption of alcohol. One of the important downstream targets of AKT is the mammalian Target Of Rapamycin in Complex 1 (mTORC