Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sophie L, Winter"'
Autor:
Steffen Klein, Benedikt H. Wimmer, Sophie L. Winter, Androniki Kolovou, Vibor Laketa, Petr Chlanda
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Using the post-correlation on-lamella cryo-CLEM workflow, Klein, Wimmer et al. show that lamellar bodies (LBs) are composed of membrane sheets frequently attached to the limiting membrane through T-junctions in ABCA3 overexpressing cells and in prima
Externí odkaz:
https://doaj.org/article/32ea53411acf49449270aa8a27ac4173
Autor:
Steffen Klein, Mirko Cortese, Sophie L. Winter, Moritz Wachsmuth-Melm, Christopher J. Neufeldt, Berati Cerikan, Megan L. Stanifer, Steeve Boulant, Ralf Bartenschlager, Petr Chlanda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture a
Externí odkaz:
https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
Autor:
Sophie L Winter, Gonen Golani, Fabio Lolicato, Melina Vallbracht, Keerthihan Thiyagarajah, Samy Sid Ahmed, Christian Lüchtenborg, Oliver T Fackler, Britta Brügger, Thomas Hoenen, Walter Nickel, Ulrich S Schwarz, Petr Chlanda
Ebola viruses (EBOVs) assemble into filamentous virions, whose shape and stability are determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via membrane fusion in late endosomes; however, the mechanism of how the remar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea7e1aaee4895820541f871cf38e841
http://hdl.handle.net/10138/358472
http://hdl.handle.net/10138/358472
Autor:
Sophie L. Winter, Gonen Golani, Fabio Lolicato, Melina Vallbracht, Keerthihan Thiyagarajah, Samy Sid Ahmed, Christian Luechtenborg, Oliver T Fackler, Britta Bruegger, Thomas Hoenen, Walter Nickel, Ulrich S Schwarz, Petr Chlanda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee6cb1a457c743c523741d44f1a9e4a
https://doi.org/10.15252/rc.2023198189
https://doi.org/10.15252/rc.2023198189
Autor:
Steffen Klein, Thorsten G. Müller, Dina Khalid, Vera Sonntag-Buck, Anke-Mareil Heuser, Bärbel Glass, Matthias Meurer, Ivonne Morales, Angelika Schillak, Andrew Freistaedter, Ina Ambiel, Sophie L. Winter, Liv Zimmermann, Tamara Naumoska, Felix Bubeck, Daniel Kirrmaier, Stephanie Ullrich, Isabel Barreto Miranda, Simon Anders, Dirk Grimm, Paul Schnitzler, Michael Knop, Hans-Georg Kräusslich, Viet Loan Dao Thi, Kathleen Börner, Petr Chlanda
Publikováno v:
Viruses, Vol 12, Iss 8, p 863 (2020)
Rapid large-scale testing is essential for controlling the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The standard diagnostic pipeline for testing SARS-CoV-2 presence in patients with an ongoing infection is pre
Externí odkaz:
https://doaj.org/article/ecb4e0dd8f1f4504be4719959baa1d69
Autor:
Sophie L. Winter, Gonen Golani, Fabio Lolicato, Melina Vallbracht, Keerthihan Thiyagarajah, Samy Sid Ahmed, Christian Lüchtenborg, Oliver T. Fackler, Britta Brügger, Thomas Hoenen, Walter Nickel, Ulrich S. Schwarz, Petr Chlanda
Ebola viruses (EBOVs) are filamentous particles, whose shape and stability are determined by the VP40 matrix. Virus entry into host cells occurs via membrane fusion in late endosomes; however, the mechanism of how the remarkably long virions undergo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55e59bca9863867b15b46cd7004d473
https://doi.org/10.1101/2022.08.24.505067
https://doi.org/10.1101/2022.08.24.505067
Autor:
Zina M. Uckeley, Magalie Mazelier, Christian Lüchtenborg, Sophie L. Winter, Paulina Schad, Petr Chlanda, Britta Brügger, Pierre-Yves Lozach
Virus–receptor interactions largely contribute to the tropism and outcome of an infection. Here, we found that the glycolipid glucosylceramide (GlcCer) is a major component of Uukuniemi phenuivirus and allows viral binding to host cells. A lipidomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4259063de2d3fe1c73774fc2bf2e1ef4
https://doi.org/10.1101/2022.08.07.502911
https://doi.org/10.1101/2022.08.07.502911
Autor:
Vibor Laketa, Steffen Klein, Sophie L. Winter, Benedikt H. Wimmer, Petr Chlanda, Androniki Kolovou
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology
Lamellar bodies (LBs) are surfactant-rich organelles in alveolar cells. LBs disassemble into a lipid-protein network that reduces surface tension and facilitates gas exchange in the alveolar cavity. Current knowledge of LB architecture is predominant
Autor:
Megan L. Stanifer, Steeve Boulant, Steffen Klein, Sophie L. Winter, Christopher J. Neufeldt, Berati Cerikan, Petr Chlanda, Moritz Wachsmuth-Melm, Mirko Cortese, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID19 pandemic, is a highly pathogenic β-coronavirus. As other coronaviruses, SARS-CoV-2 is enveloped, replicates in the cytoplasm and assembles at intracellu
Autor:
Janosch Hennig, Pawel Masiewicz, Mikhail M. Savitski, Frank Gabel, Jochen S. Hub, Mandy Rettel, Bernd Simon, Brice Murciano, Jakub Macošek, Kathryn Perez, Miloš T. Ivanović, Inga Loedige, Sophie L. Winter, Pravin Kumar Ankush Jagtap, Jaelle Foot, Johanna-Barbara Linse, Karine Lapouge
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (15), pp.8866-8885. ⟨10.1093/nar/gkab635⟩
Nucleic Acids Research, 2021, 49 (15), pp.8866-8885. ⟨10.1093/nar/gkab635⟩
Nucleic acids research 49(15), 8866-8885 (2021). doi:10.1093/nar/gkab635
Nucleic Acids Research, Oxford University Press, 2021, 49 (15), pp.8866-8885. ⟨10.1093/nar/gkab635⟩
Nucleic Acids Research, 2021, 49 (15), pp.8866-8885. ⟨10.1093/nar/gkab635⟩
Nucleic acids research 49(15), 8866-8885 (2021). doi:10.1093/nar/gkab635
A key regulatory process during Drosophila development is the localized suppression of the hunchback mRNA translation at the posterior, which gives rise to a hunchback gradient governing the formation of the anterior-posterior body axis. This suppres