Výsledky vyhledávání - "Sophie J. Rewey"

Dual orexin antagonist normalized sleep homeostatic drive, enhanced GABAergic inhibition, and suppressed seizures after traumatic brain injury

Autor: Sruthi R Konduru, Jesse R Isaacson, Danny J Lasky, Zihao Zhou, Rohan K Rao, Swati S Vattem, Sophie J Rewey, Mathew V Jones, Rama K Maganti

Publikováno v: Sleep. 45

Study Objectives Traumatic brain injury (TBI) can result in posttraumatic epilepsy (PTE) and sleep disturbances. We hypothesized that treatment with sleep aids after TBI can ameliorate PTE. Methods CD-1 mice underwent controlled cortical impact (CCI)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b80422f1d8f0f37d33c07e3a98efc26
https://doi.org/10.1093/sleep/zsac238

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Dual orexin antagonist DORA-22 suppressed posttraumatic seizures and enhances GABAergic inhibition in dentate granule cells

Autor: Sruthi R. Konduru, Jesse R. Isaacson, Zihao Zhou, Rohan K. Rao, Danny J. Lasky, Swati S. Vattem, Sophie J. Rewey, Mathew V. Jones, Rama K. Maganti

BackgroundTraumatic brain injury (TBI) can result in posttraumatic epilepsy (PTE) and sleep disturbances. We hypothesized that treatment with sleep aids after TBI can ameliorate PTE.MethodsCD-1 mice underwent controlled cortical impact (CCI), sham cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d0b3b3e8244aa7489dd2825ec72b92f
https://doi.org/10.1101/2022.04.17.488582

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