Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sophie J. Gilbert"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Osteoarthritic (OA) pain affects 18% of females and 9.6% of males aged over 60 worldwide, with 62% of all OA patients being women. The molecular drivers of sex-based differences in OA are unknown. Bone is intricately coupled with the sensory nervous
Externí odkaz:
https://doaj.org/article/7dc598da4c1e4ed4925f41b01091c0bc
Autor:
Sophie J. Gilbert, Jamie Soul, Yao Hao, Hua Lin, Katarzyna A. Piróg, Jonathan Coxhead, Krutik Patel, Matt J. Barter, David A. Young, Emma J. Blain
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/7bf1a9b2e6434f3e83dabd80f2d1187f
Autor:
Sophie J. Gilbert, Ryan Jones, Ben J. Egan, Cleo Selina Bonnet, Sam L. Evans, Deborah J. Mason
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionChanges to bone physiology play a central role in the development of osteoarthritis with the mechanosensing osteocyte releasing factors that drive disease progression. This study developed a humanised in vitro model to detect osteocyte re
Externí odkaz:
https://doaj.org/article/60634a5c91fd4126a4250923903c1936
Autor:
Jonathan H. Tobias, Emma L. Duncan, Erika Kague, Chrissy L. Hammond, Celia L. Gregson, Duncan Bassett, Graham R. Williams, Josine L. Min, Tom R. Gaunt, David Karasik, Claes Ohlsson, Fernando Rivadeneira, James R. Edwards, Fadil M. Hannan, John P. Kemp, Sophie J. Gilbert, Nerea Alonso, Neelam Hassan, Juliet E. Compston, Stuart H. Ralston
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
The discovery that sclerostin is the defective protein underlying the rare heritable bone mass disorder, sclerosteosis, ultimately led to development of anti-sclerostin antibodies as a new treatment for osteoporosis. In the era of large scale GWAS, m
Externí odkaz:
https://doaj.org/article/213a3053bba14147b16d8929aed76dac
Autor:
Madhawi Alanazi, Martha B. Alvarez-Elizondo, Kristi S. Anseth, Salma Ayoub, Akshay Badakere, Emma J. Blain, Rachel M. Buchanan, Alexander W. Caulk, Yunfeng Chen, Nikhil S. Choudhari, Vivek P. Dave, Eimear B. Dolan, Giovanni Ferrari, Sophie J. Gilbert, Jason P. Gleghorn, Geoffrey C. Gurtner, Jay D. Humphrey, Doorgesh Sharma Jokhun, Lining A. Ju, Alex Khang, Megan L. Killian, Abhishek Kumar, Sun Hyung Kwon, Chung-Hao Lee, Hui Li, Zhenhai Li, Ekta Makhija, Laoise M. McNamara, Ashik Mohamed, Ashraf M. Mohieldin, Derek Nankivil, Andromeda M. Nauli, Surya M. Nauli, Jagannath Padmanabhan, Amanda J. Page, Sunil Punjabi, A.V. Radhakrishnan, Bruno V. Rego, Ashutosh Richhariya, Rebecca A. Rolfe, Rakefet Rozen, Michael S. Sacks, Virender S. Sangwan, G.V. Shivashankar, George Tellides, Bhavani P. Thampatty, William J. Tyler, Stefaan W. Verbruggen, James H.-C. Wang, Daphne Weihs, Cheng Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1703888e82907ec2b968b42dde5ec229
https://doi.org/10.1016/b978-0-12-812952-4.09991-8
https://doi.org/10.1016/b978-0-12-812952-4.09991-8
Autor:
Sophie J, Gilbert, Cleo S, Bonnet, Paulina, Stadnik, Victor C, Duance, Deborah J, Mason, Emma J, Blain
Publikováno v:
Journal of Orthopaedic Research
Joint injury is the predominant risk factor for post‐traumatic osteoarthritis development (PTOA). Several non‐invasive mouse models mimicking human PTOA investigate molecular mechanisms of disease development; none have characterized the inflamma