Zobrazeno 1 - 10
of 4 546
pro vyhledávání: '"Sophie J"'
Autor:
Sophie J. Heseltine, Gregory J. Billenness, Heather L Martin, Christian Tiede, Anna A.S. Tang, Eleanor Foy, Grace Reddy, Naomi Gibson, Matt Johnson, Michael E. Webb, Michael J. McPherson, Darren C. Tomlinson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Despite SH2 domains, being pivotal in protein interactions linked to various diseases like cancer, we lack specific research tools for intracellular assays. Understanding SH2-mediated interactions and creating effective inhibitors requires t
Externí odkaz:
https://doaj.org/article/897c250a45ca4c918029c347c9003027
Intestinal microbiology and urinary tract infection associated risk in long-term aged care residents
Autor:
Sophie J. Miller, Lucy Carpenter, Steven L. Taylor, Steve L. Wesselingh, Jocelyn M. Choo, Andrew P. Shoubridge, Lito E. Papanicolas, Geraint B. Rogers, GRACE Investigator Group
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-10 (2024)
Abstract Background Urinary tract infections (UTI) are the most frequently diagnosed infection in residents of long-term care and are a major risk factor for urosepsis, hospitalisation, and death. Translocation of gut pathobionts into the urinary tra
Externí odkaz:
https://doaj.org/article/8297cfad80974224ac454cc629a77843
Autor:
Christy W. LaFlamme, Cassandra Rastin, Soham Sengupta, Helen E. Pennington, Sophie J. Russ-Hall, Amy L. Schneider, Emily S. Bonkowski, Edith P. Almanza Fuerte, Talia J. Allan, Miranda Perez-Galey Zalusky, Joy Goffena, Sophia B. Gibson, Denis M. Nyaga, Nico Lieffering, Malavika Hebbar, Emily V. Walker, Daniel Darnell, Scott R. Olsen, Pandurang Kolekar, Mohamed Nadhir Djekidel, Wojciech Rosikiewicz, Haley McConkey, Jennifer Kerkhof, Michael A. Levy, Raissa Relator, Dorit Lev, Tally Lerman-Sagie, Kristen L. Park, Marielle Alders, Gerarda Cappuccio, Nicolas Chatron, Leigh Demain, David Genevieve, Gaetan Lesca, Tony Roscioli, Damien Sanlaville, Matthew L. Tedder, Sachin Gupta, Elizabeth A. Jones, Monika Weisz-Hubshman, Shamika Ketkar, Hongzheng Dai, Kim C. Worley, Jill A. Rosenfeld, Hsiao-Tuan Chao, Undiagnosed Diseases Network, Geoffrey Neale, Gemma L. Carvill, University of Washington Center for Rare Disease Research, Zhaoming Wang, Samuel F. Berkovic, Lynette G. Sadleir, Danny E. Miller, Ingrid E. Scheffer, Bekim Sadikovic, Heather C. Mefford
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sequence-based genetic testing identifies causative variants in ~ 50% of individuals with developmental and epileptic encephalopathies (DEEs). Aberrant changes in DNA methylation are implicated in various neurodevelopmental disorders but rem
Externí odkaz:
https://doaj.org/article/56ab879163324f04934308a670c8a49d
Autor:
Sophie J. Wang, Zhongxiu Hu, Collin Li, Xinzi He, Chenglin Zhu, Yin Wang, Usama Sattar, Vahid Bazojoo, Hui Yi Ng He, Jon D. Blumenfeld, Martin R. Prince
Publikováno v:
Tomography, Vol 10, Iss 7, Pp 1148-1158 (2024)
Background: Pancreatic cysts in autosomal dominant polycystic kidney disease (ADPKD) correlate with PKD2 mutations, which have a different phenotype than PKD1 mutations. However, pancreatic cysts are commonly overlooked by radiologists. Here, we auto
Externí odkaz:
https://doaj.org/article/09142d2095254124bf1253135652c0c5
Publikováno v:
Canadian Journal of Pain, Vol 8, Iss 1 (2024)
Background As an emerging approach, arts-based research holds potential to advance understanding of the complex and multidimensional experiences of chronic pain and means of communicating this experiential evidence. This scoping review aimed to map a
Externí odkaz:
https://doaj.org/article/e8e810405fe7498f98699f8fddde31d0
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Osteoarthritic (OA) pain affects 18% of females and 9.6% of males aged over 60 worldwide, with 62% of all OA patients being women. The molecular drivers of sex-based differences in OA are unknown. Bone is intricately coupled with the sensory nervous
Externí odkaz:
https://doaj.org/article/7dc598da4c1e4ed4925f41b01091c0bc
Autor:
Sophie J. Gilbert, Jamie Soul, Yao Hao, Hua Lin, Katarzyna A. Piróg, Jonathan Coxhead, Krutik Patel, Matt J. Barter, David A. Young, Emma J. Blain
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/7bf1a9b2e6434f3e83dabd80f2d1187f
Autor:
Sophie J. Gilbert, Ryan Jones, Ben J. Egan, Cleo Selina Bonnet, Sam L. Evans, Deborah J. Mason
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionChanges to bone physiology play a central role in the development of osteoarthritis with the mechanosensing osteocyte releasing factors that drive disease progression. This study developed a humanised in vitro model to detect osteocyte re
Externí odkaz:
https://doaj.org/article/60634a5c91fd4126a4250923903c1936
Autor:
Prashant D. Tailor, MD, Timothy T. Xu, MD, Blake H. Fortes, MD, Raymond Iezzi, MD, Timothy W. Olsen, MD, Matthew R. Starr, MD, Sophie J. Bakri, MD, Brittni A. Scruggs, MD, PhD, Andrew J. Barkmeier, MD, Sanjay V. Patel, MD, Keith H. Baratz, MD, Ashlie A. Bernhisel, MD, Lilly H. Wagner, MD, Andrea A. Tooley, MD, Gavin W. Roddy, MD, PhD, Arthur J. Sit, MD, Kristi Y. Wu, MD, Erick D. Bothun, MD, Sasha A. Mansukhani, MBBS, Brian G. Mohney, MD, John J. Chen, MD, PhD, Michael C. Brodsky, MD, Deena A. Tajfirouz, MD, Kevin D. Chodnicki, MD, Wendy M. Smith, MD, Lauren A. Dalvin, MD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 1, Pp 119-128 (2024)
Objective: To determine the appropriateness of ophthalmology recommendations from an online chat-based artificial intelligence model to ophthalmology questions. Patients and Methods: Cross-sectional qualitative study from April 1, 2023, to April 30,
Externí odkaz:
https://doaj.org/article/b989e4cca22a42128f8a8334faf81ad8
Autor:
Sophie J. Featherby, Camille Ettelaie
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionMicrovesicles (MV) released by endothelial cells (EC) following injury or inflammation contain tissue factor (TF) and mediate communication with the underlying smooth muscle cells (SMC). Ser253-phosphorylated TF co-localizes with filamin
Externí odkaz:
https://doaj.org/article/cff5534a0e06457f91a767c663e2afb1