Genomic and RT-qPCR analysis of trimethoprim-sulfamethoxazole and meropenem resistance in Burkholderia pseudomallei clinical isolates.

Autor: Marine Schnetterle, Olivier Gorgé, Flora Nolent, Aïda Boughammoura, Véronique Sarilar, Cécile Vigier, Sophie Guillier, Lionel Koch, Nicolas Degand, Vincent Ramisse, Xavier Tichadou, Maria Girleanu, Anne-Laure Favier, Eric Valade, Fabrice Biot, Fabienne Neulat-Ripoll

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0008913 (2021)

BackgroundMelioidosis is an endemic disease in southeast Asia and northern Australia caused by the saprophytic bacteria Burkholderia pseudomallei, with a high mortality rate. The clinical presentation is multifaceted, with symptoms ranging from acute

Externí odkaz: https://doaj.org/article/2084023be3f44dbb920362d7c855a217

APOBEC3F is the main source of editing identified during the 2022 outbreak of human monkeypox virus

Autor: Rodolphe Suspène, Kyle A. Raymond, Laetitia Boutin, Sophie Guillier, Frédéric Lemoine, Olivier Ferraris, Jean-Nicolas Tournier, Frédéric Iseni, Etienne Simon-Lorière, Jean-Pierre Vartanian

On May 6, 2022, a powerful outbreak of monkeypox virus (MPXV) had been reported outside of Africa, with many continuing new cases being reported around the world. Analysis of mutations among the two different lineages present in the 2021 and 2022 out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2474bf53aa5d634ba1236cb5bf373a7
https://doi.org/10.1101/2023.01.06.522979

Transcriptomic studies and assessment of Yersinia pestis reference genes in various conditions

Autor: Fabienne Neulat-Ripoll, Florent Sebbane, Olivier Gorgé, Flora Nolent, Lionel Koch, Fabrice Biot, Sophie Guillier, Thomas Poyot, Estelle Soulé, Eric Valade, Marine Schnetterle

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.2501. ⟨10.1038/s41598-019-39072-x⟩
Scientific Reports, 2019, 9 (1), pp.2501. ⟨10.1038/s41598-019-39072-x⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

International audience; Reverse transcription quantitative real-time polymerase chain reaction (Rt-qpCR) is a very sensitive widespread technique considered as the gold standard to explore transcriptional variations. While a particular methodology ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbf1f6c1a37ac4dbfa002dae5634584
https://hal-amu.archives-ouvertes.fr/hal-02498186

Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets

Autor: Jerónimo Bravo, Christophe Perez, Guillermo Montoya, Francois Stricher, Luis Serrano, Francisco J. Blanco, Sandra Rolland, Amélie Patin, Anne-Sophie Petit, Sylvain Arnould, Emmanuel Lacroix, Aymeric Duclert, Sophie Guillier, Jesús Prieto, Jean-Charles Epinat, Patrick Chames, Frédéric Pâques, Philippe Duchateau

Publikováno v: Journal of Molecular Biology. 355:443-458

The last decade has seen the emergence of a universal method for precise and efficient genome engineering. This method relies on the use of sequence-specific endonucleases such as homing endonucleases. The structures of several of these proteins are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddb06c8d7fd709a2ee5c267fe63aaee
https://doi.org/10.1016/j.jmb.2005.10.065