Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Sophie Giorgetti"'
Autor:
Maider Varela-Guruceaga, Elise Belaidi, Lucie Lebeau, Ella Aka, Ramaroson Andriantsitohaina, Sophie Giorgetti-Peraldi, Claire Arnaud, Soazig Le Lay
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders. In humans, an association between OSA and
Externí odkaz:
https://doaj.org/article/da02a888ba3340869a72b8842ef792b9
Autor:
Béatrice Cambien, Kevin Lebrigand, Alberto Baeri, Nicolas Nottet, Catherine Compin, Audrey Lamit, Olivier Ferraris, Christophe N Peyrefitte, Virginie Magnone, Jérôme Henriques, Laure-Emmanuelle Zaragosi, Sophie Giorgetti-Peraldi, Frédéric Bost, Marine Gautier-Isola, Roger Rezzonico, Pascal Barbry, Robert Barthel, Bernard Mari, Georges Vassaux
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008660 (2020)
Mammary carcinoma, including triple-negative breast carcinomas (TNBC) are tumor-types for which human and canine pathologies are closely related at the molecular level. The efficacy of an oncolytic vaccinia virus (VV) was compared in low-passage prim
Externí odkaz:
https://doaj.org/article/198a1a51898d44c0979a58f01abe50b5
Autor:
Florian A. Britto, Fabienne Cortade, Yassine Belloum, Marine Blaquière, Yann S. Gallot, Aurélie Docquier, Allan F. Pagano, Elodie Jublanc, Nadia Bendridi, Christelle Koechlin-Ramonatxo, Béatrice Chabi, Marc Francaux, François Casas, Damien Freyssenet, Jennifer Rieusset, Sophie Giorgetti-Peraldi, Gilles Carnac, Vincent Ollendorff, François B. Favier
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background Skeletal muscle atrophy is a common feature of numerous chronic pathologies and is correlated with patient mortality. The REDD1 protein is currently recognized as a negative regulator of muscle mass through inhibition of the Akt/m
Externí odkaz:
https://doaj.org/article/fec9c00871564efe8cdbac8f34f294b2
Autor:
Simona Cataldi, Marianna Aprile, Daniela Melillo, Inès Mucel, Sophie Giorgetti-Peraldi, Mireille Cormont, Paola Italiani, Matthias Blüher, Jean-François Tanti, Alfredo Ciccodicola, Valerio Costa
Publikováno v:
Cells, Vol 11, Iss 1, p 42 (2021)
Low-grade chronic inflammation and reduced differentiation capacity are hallmarks of hypertrophic adipose tissue (AT) and key contributors of insulin resistance. We identified PPARGΔ5 as a dominant-negative splicing isoform overexpressed in the AT o
Externí odkaz:
https://doaj.org/article/d5e0a62dcf1a4c379ece0afb622707a1
Autor:
Faustine Pastor, Karine Dumas, Marie-Astrid Barthélémy, Claire Regazzetti, Noémie Druelle, Pascal Peraldi, Mireille Cormont, Jean-François Tanti, Sophie Giorgetti-Peraldi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract In response to endotoxemia, the organism triggers an inflammatory response, and the visceral adipose tissue represents a major source of proinflammatory cytokines. The regulation of inflammation response in the adipose tissue is thus of cruc
Externí odkaz:
https://doaj.org/article/ef7e6eae90454a8ba2c1f73c9ea64b63
Publikováno v:
Cells, Vol 9, Iss 10, p 2251 (2020)
Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that the primary cilium, an antenna-shap
Externí odkaz:
https://doaj.org/article/26605ecd769440d49a85f9c982b2b31c
Autor:
Claire Regazzetti, Karine Dumas, Yannick Le Marchand-Brustel, Pascal Peraldi, Jean-François Tanti, Sophie Giorgetti-Peraldi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52154 (2012)
REDD1 (Regulated in development and DNA damage response 1) is a hypoxia and stress response gene and is a negative regulator of mTORC1. Since mTORC1 is involved in the negative feedback loop of insulin signaling, we have studied the role of REDD1 on
Externí odkaz:
https://doaj.org/article/90d120c1fadd4297b6763bbc94a3f677
Autor:
Magali Plaisant, Sophie Giorgetti-Peraldi, Marike Gabrielson, Agnes Loubat, Christian Dani, Pascal Peraldi
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16798 (2011)
Human mesenchymal stem cells (hMSC) have the ability to differentiate into osteoblasts, adipocytes and chondrocytes. We have previously shown that hMSC were endowed with a basal level of Hedgehog signaling that decreased after differentiation of thes
Externí odkaz:
https://doaj.org/article/b3f91662e1404d1a88c2f4da9e6dea70
Autor:
Marion Berenguer, Laurène Martinez, Sophie Giorgetti-Peraldi, Yannick Le Marchand-Brustel, Roland Govers
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15560 (2010)
In response to insulin, glucose transporter GLUT4 translocates from intracellular compartments towards the plasma membrane where it enhances cellular glucose uptake. Here, we show that sera from various species contain a factor that dose-dependently
Externí odkaz:
https://doaj.org/article/2d772a5837b04426a8377b4ab8dda66b
Autor:
Frédéric Bost, Sophie Giorgetti-Peraldi, Jean-François Tanti, Patrick Auberger, Yannick Le Marchand-Brustel, Kathiane Laurent, Guillaume Robert, Claire Regazzetti, Isaam Ben Sahra
Supplementary Figures 1-3 from Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a4b6c05e3be90a262e52fe8eef13ec
https://doi.org/10.1158/0008-5472.22386404.v1
https://doi.org/10.1158/0008-5472.22386404.v1