Comparative effects of overproducing the AraC-type transcriptional regulators MarA, SoxS, RarA and RamA on antimicrobial drug susceptibility in Klebsiella pneumoniae

Autor: Ching Hei Phoebe Cheung, Sophie G Isaac, Juan-Carlos Jiménez-Castellanos, James Brown, Wan Nur Ismah Wan Ahmad Kamil, Thamarai Schneiders, Kate J. Heesom, Maryann S Tobin, Matthew B. Avison

Publikováno v: Jiménez-Castellanos, J-C, Wan Ahmad Kamil, W N I, Cheung, C H P, Tobin, M S, Brown, J, Isaac, S G, Heesom, K J, Schneiders, T & Avison, M B 2016, ' Comparative effects of overproducing the AraC-type transcriptional regulators MarA, SoxS, RarA and RamA on antimicrobial drug susceptibility in Klebsiella pneumoniae ', Journal of Antimicrobial Chemotherapy, vol. 71, no. 7, pp. 1820-1825 . https://doi.org/10.1093/jac/dkw088

OBJECTIVES: In Klebsiella pneumoniae, overproduction of RamA and RarA leads to increased MICs of various antibiotics; MarA and SoxS are predicted to perform a similar function. We have compared the relative effects of overproducing these four AraC-ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd0357962952e41015f0c669723aec3
https://pubmed.ncbi.nlm.nih.gov/27029850