Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sophie Ellermann"'
Autor:
Juri Na, Joseph A. Newman, Chee Kin Then, Junetha Syed, Iolanda Vendrell, Ignacio Torrecilla, Sophie Ellermann, Kristijan Ramadan, Roman Fischer, Anne E. Kiltie
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-17 (2021)
Abstract The human MRE11/RAD50/NBS1 (MRN) complex plays a crucial role in sensing and repairing DNA DSB. MRE11 possesses dual 3′−5′ exonuclease and endonuclease activity and forms the core of the multifunctional MRN complex. We previously ident
Externí odkaz:
https://doaj.org/article/3103fd513d43413eb4a4915b79d69200
Autor:
Anne E. Kiltie, Benedikt M. Kessler, Martin Kerr, Rebecca Konietzny, Sophie Ellermann, Blaz Groselj, Sarah J. Jevons, Judith Nicholson
Supplemental figures 1-5: S1 - Identification of MRE11 truncation by mass spectrometry and western blot quantification from Fig 1A. S2 - Western blots of protein levels after chloroquine treatment and densitometry of MRE11 levels after PAN and cycloh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6191f00590a10b1ad275359899ebe480
https://doi.org/10.1158/0008-5472.22414497
https://doi.org/10.1158/0008-5472.22414497
Autor:
Anne E. Kiltie, Benedikt M. Kessler, Martin Kerr, Rebecca Konietzny, Sophie Ellermann, Blaz Groselj, Sarah J. Jevons, Judith Nicholson
The MRE11/RAD50/NBS1 (MRN) complex mediates DNA repair pathways, including double-strand breaks induced by radiotherapy. Meiotic recombination 11 homolog (MRE11) is downregulated by histone deacetylase inhibition (HDACi), resulting in reduced levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f35da1633447ff87b420157ed1fe5091
https://doi.org/10.1158/0008-5472.c.6508998.v1
https://doi.org/10.1158/0008-5472.c.6508998.v1
Autor:
Anne E. Kiltie, Chee Kin Then, Sophie Ellermann, J.A. Newman, Junetha Syed, Ignacio Torrecilla, Iolanda Vendrell, Kristijan Ramadan, Juri Na, Roman Fischer
Publikováno v:
Cell Death & Disease
Cell death & disease, 12(2). Nature Publishing Group
Cell Death and Disease, Vol 12, Iss 2, Pp 1-17 (2021)
Cell death & disease, 12(2). Nature Publishing Group
Cell Death and Disease, Vol 12, Iss 2, Pp 1-17 (2021)
The human MRE11/RAD50/NBS1 (MRN) complex plays a crucial role in sensing and repairing DNA DSB. MRE11 possesses dual 3′−5′ exonuclease and endonuclease activity and forms the core of the multifunctional MRN complex. We previously identified a C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e55e65e62a3c0343b3c0eabc9e8bfa
https://doi.org/10.1038/s41419-021-03437-w
https://doi.org/10.1038/s41419-021-03437-w
Autor:
Olivier Deschaume, Kasper Eersels, Marloes Peeters, Erik Steen Redeker, Bart van Grinsven, Aleksandra Kordek, Hanne Diliën, Thomas J. Cleij, Sophie Ellermann, Carmen Bartic, Patrick Wagner, Onno Akkermans
Publikováno v:
ACS sensors, 1(9), 1140-1147. American Chemical Society
This work focuses on the development of a label-free biomimetic sensor for the specific and selective detection of bacteria. The platform relies on the rebinding of bacteria to synthetic cell receptors, made by surface imprinting of polyurethane-coat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d038e27127e5fe2b40be25cc0859dd7c
https://doi.org/10.1021/acssensors.6b00435
https://doi.org/10.1021/acssensors.6b00435
Autor:
Judith, Nicholson, Sarah J, Jevons, Blaz, Groselj, Sophie, Ellermann, Rebecca, Konietzny, Martin, Kerr, Benedikt M, Kessler, Anne E, Kiltie
Publikováno v:
Cancer research. 77(11)
The MRE11/RAD50/NBS1 (MRN) complex mediates DNA repair pathways, including double-strand breaks induced by radiotherapy. Meiotic recombination 11 homolog (MRE11) is downregulated by histone deacetylase inhibition (HDACi), resulting in reduced levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6914764a29bbe8508ae99abb46b8fb06
https://pubmed.ncbi.nlm.nih.gov/28363998
https://pubmed.ncbi.nlm.nih.gov/28363998