Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sophie D Lefevre"'
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48982 (2012)
BACKGROUND: Chronological aging of yeast cells is commonly used as a model for aging of human post-mitotic cells. The yeast Saccharomyces cerevisiae grown on glucose in the presence of ammonium sulphate is mainly used in yeast aging research. We have
Externí odkaz:
https://doaj.org/article/59138d2b1472475cb66db098a269343e
Autor:
Florencia Orrico, Sandrine Laurance, Ana C. Lopez, Sophie D. Lefevre, Leonor Thomson, Matias N. Möller, Mariano A. Ostuni
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1262 (2023)
Red cell diseases encompass a group of inherited or acquired erythrocyte disorders that affect the structure, function, or production of red blood cells (RBCs). These disorders can lead to various clinical manifestations, including anemia, hemolysis,
Externí odkaz:
https://doaj.org/article/6b020c8550ec4a36ab03313ead6c3b1a
Autor:
Martina Moras, Claude Hattab, Pedro Gonzalez-Menendez, Claudio M. Fader, Michael Dussiot, Jerome Larghero, Caroline Le Van Kim, Sandrina Kinet, Naomi Taylor, Sophie D. Lefevre, Mariano A. Ostuni
Publikováno v:
Haematologica, Vol 107, Iss 1 (2021)
Erythroblast maturation in mammals is dependent on organelle clearance throughout terminal erythropoiesis. We studied the role of the outer mitochondrial membrane protein voltage-dependent anion channel-1 (VDAC1) in human terminal erythropoiesis. We
Externí odkaz:
https://doaj.org/article/4cedd1eb7aa44491a81e50206e22b882
Autor:
Maria Alejandra Lizarralde-Iragorri, Sophie D. Lefevre, Sylvie Cochet, Sara El Hoss, Valentine Brousse, Anne Filipe, Michael Dussiot, Slim Azouzi, Caroline Le Van Kim, Fernando Rodrigues-Lima, Olivier Français, Bruno Le Pioufle, Thomas Klei, Robin van Bruggen, Wassim El Nemer
Publikováno v:
Haematologica, Vol 106, Iss 9 (2020)
Vaso-occlusive crises are the hallmark of sickle cell disease (SCD). They are believed to occur in two steps, starting with adhesion of deformable low-dense red blood cells (RBCs), or other blood cells such as neutrophils, to the wall of post-capilla
Externí odkaz:
https://doaj.org/article/f8e47790cc614bceaf1a6c86c6db0d5f
Autor:
Martina Moras, Claude Hattab, Pedro Gonzalez-Menendez, Suella Martino, Jerome Larghero, Caroline Le Van Kim, Sandrina Kinet, Naomi Taylor, Sophie D. Lefevre, Mariano A. Ostuni
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9066 (2020)
Translocator protein (TSPO) and voltage dependent anion channels (VDAC) are two proteins forming a macromolecular complex in the outer mitochondrial membrane that is involved in pleiotropic functions. Specifically, these proteins were described to re
Externí odkaz:
https://doaj.org/article/75526b71cb094dbf850da50ca55c1367
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5263 (2020)
Human erythropoiesis is a complex process leading to the production of mature, enucleated erythrocytes (RBCs). It occurs mainly at bone marrow (BM), where hematopoietic stem cells (HSCs) are engaged in the early erythroid differentiation to commit in
Externí odkaz:
https://doaj.org/article/5c58ec96cea249ebbaca36e68c017fa6
Autor:
Marie-Françoise O’Donohue, Lydie Da Costa, Marco Lezzerini, Sule Unal, Clément Joret, Marije Bartels, Eva Brilstra, Marijn Scheijde-Vermeulen, Ludivine Wacheul, Kim De Keersmaecker, Stijn Vereecke, Veerle Labarque, Manon Saby, Sophie D. Lefevre, Jessica Platon, Nathalie Montel-Lehry, Nathalie Laugero, Eric Lacazette, Koen van Gassen, Riekelt H. Houtkooper, Pelin Ozlem Simsek-Kiper, Thierry Leblanc, Nese Yarali, Arda Cetinkaya, Nurten A. Akarsu, Pierre-Emmanuel Gleizes, Denis L. J. Lafontaine, Alyson W. MacInnes
Publikováno v:
Blood, 139(21), 3111-3126. American Society of Hematology
O'Donohue, M-F, da Costa, L, Lezzerini, M, Unal, S, Joret, C, Bartels, M, Brilstra, E, Scheijde-Vermeulen, M, Wacheul, L, de Keersmaecker, K, Vereecke, S, Labarque, V, Saby, M, Lefevre, S D, Platon, J, Montel-Lehry, N, Laugero, N, Lacazette, E, van Gassen, K, Houtkooper, R H, Simsek-Kiper, P O, Leblanc, T, Yarali, N, Cetinkaya, A, Akarsu, N A, Gleizes, P-E, Lafontaine, D L J & MacInnes, A W 2022, ' HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia ', Blood, vol. 139, no. 21, pp. 3111-3126 . https://doi.org/10.1182/blood.2021011846
O'Donohue, M-F, da Costa, L, Lezzerini, M, Unal, S, Joret, C, Bartels, M, Brilstra, E, Scheijde-Vermeulen, M, Wacheul, L, de Keersmaecker, K, Vereecke, S, Labarque, V, Saby, M, Lefevre, S D, Platon, J, Montel-Lehry, N, Laugero, N, Lacazette, E, van Gassen, K, Houtkooper, R H, Simsek-Kiper, P O, Leblanc, T, Yarali, N, Cetinkaya, A, Akarsu, N A, Gleizes, P-E, Lafontaine, D L J & MacInnes, A W 2022, ' HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia ', Blood, vol. 139, no. 21, pp. 3111-3126 . https://doi.org/10.1182/blood.2021011846
The congenital bone marrow failure syndrome Diamond-Blackfan anemia (DBA) is typically associated with variants in ribosomal protein (RP) genes impairing erythroid cell development. Here we report multiple individuals with biallelic HEATR3 variants e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4100cf484e864275fa42206f6a6809
https://research.vumc.nl/en/publications/7731263a-7b25-4244-b994-0a42cb7e6400
https://research.vumc.nl/en/publications/7731263a-7b25-4244-b994-0a42cb7e6400
Autor:
Alice Dussouchaud, Julieta Jacob, Charles Secq, Jean-Marc Verbavatz, Martina Moras, Jérôme Larghero, Claudio M. Fader, Mariano A. Ostuni, Sophie D. Lefevre
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Throughout mammal erythroid differentiation, erythroblasts undergo enucleation and organelle clearance becoming mature red blood cell. Organelles are cleared by autophagic pathways non-specifically targeting organelles and cytosolic content or by spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2789eb9b7f305533a34625c9e8130c
https://www.frontiersin.org/articles/10.3389/fphys.2021.791691/full
https://www.frontiersin.org/articles/10.3389/fphys.2021.791691/full
Autor:
Alice, Dussouchaud, Julieta, Jacob, Charles, Secq, Jean-Marc, Verbavatz, Martina, Moras, Jérôme, Larghero, Claudio M, Fader, Mariano A, Ostuni, Sophie D, Lefevre
Publikováno v:
Frontiers in physiology. 12
Throughout mammal erythroid differentiation, erythroblasts undergo enucleation and organelle clearance becoming mature red blood cell. Organelles are cleared by autophagic pathways non-specifically targeting organelles and cytosolic content or by spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4976030b6f2d1daad5172497e690c94
https://pubmed.ncbi.nlm.nih.gov/35222062
https://pubmed.ncbi.nlm.nih.gov/35222062
Autor:
Sophie D. Lefevre, Mariano A. Ostuni, Claude Hattab, Vincent Jullien, Thibaud Lefebvre, Martina Moras, Suella Martino, Marie-Hélène Odièvre, Caroline Le Van Kim, Laurent Gouya, Jean-Benoît Arlet
Publikováno v:
British journal of haematologyReferences. 193(5)
Sickle cell disease (SCD) is characterised by chronic haemolysis and oxidative stress. Herein, we investigated 30 SCD patients and found 40% with elevated mitochondria levels (SS-mito+ ) in their mature red blood cells, while 60% exhibit similar mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41df0767aa9960a1f93b31747ce8c946
https://pubmed.ncbi.nlm.nih.gov/33754349
https://pubmed.ncbi.nlm.nih.gov/33754349