Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sophie Couvé-Privat"'
Autor:
Akira Yasui, Tirzah Braz Petta, Patricia Kannouche, Emmanuelle Despras, Anastasia Zlatanou, Sophie Couvé-Privat, Satoshi Nakajima, Alain Sarasin, Alexander A. Ishchenko
Publikováno v:
The EMBO Journal. 27:2883-2895
Human DNA polymerase iota (poliota) is a unique member of the Y-family of specialised polymerases that displays a 5'deoxyribose phosphate (dRP) lyase activity. Although poliota is well conserved in higher eukaryotes, its role in mammalian cells remai
Publikováno v:
Cancer Letters. 225:181-192
The development of basal cell carcinoma, the commonest human cancer in fair skinned populations, is clearly associated with constitutive activation of sonic hedgehog signaling. Insight into the genesis of BCC came from the identification of germline
Publikováno v:
Nucleic Acids Research
Interstrand cross-link (ICL) is a covalent modification of both strands of DNA, which prevents DNA strand separation during transcription and replication. Upon photoactivation 8-methoxypsoralen (8-MOP+UVA) alkylates both strands of DNA duplex at the
Publikováno v:
Oxidative Damage to Nucleic Acids ISBN: 9780387729732
Aerobic respiration and exogenous factors such as ionizing radiation and drugs generate reactive oxygen species (ROS). DNA has limited chemical stability and it is one of the most biologically important targets of ROS.1 Oxidative DNA lesions are beli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fb962b4e30a7e22e0ceb1d8b32cdc46
https://doi.org/10.1007/978-0-387-72974-9_4
https://doi.org/10.1007/978-0-387-72974-9_4
Autor:
Laurent Gros, Murat Saparbaev, Hiroshi Ide, Stéphane Daviet, Sophie Couvé-Privat, Kazuo Shinozuka, Alexander A. Ishchenko
Publikováno v:
DNA repair. 6(1)
Most common point mutations occurring spontaneously or induced by ionizing radiation are C--T transitions implicating cytosine as the target. Oxidative cytosine derivatives are the most abundant and mutagenic DNA damage induced by oxidative stress. B
Autor:
Alain Sarasin, Bakar Bouadjar, Josée Coulombe, Leela Daya-Grosjean, Martial Ruat, Sophie Couvé-Privat, Marie-Françoise Avril, Sophie Queille, Elisabeth Traiffort, Marc Le Bret
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2004, 64 (10), pp.3559-65. ⟨10.1158/0008-5472.CAN-03-4040⟩
Cancer Research, American Association for Cancer Research, 2004, 64 (10), pp.3559-65. ⟨10.1158/0008-5472.CAN-03-4040⟩
Altered sonic hedgehog (SHH) signaling is crucial in the development of basal cell carcinomas (BCC), the most common human cancer. Mutations in SHH signal transducers, PATCHED and SMOOTHENED, have already been identified, but SHH mutations are extrem
Autor:
Sophie, Couvé-Privat, Bakar, Bouadjar, Marie Françoise, Avril, Alain, Sarasin, Leela, Daya-Grosjean
Publikováno v:
Cancer research. 62(24)
The Sonic hedgehog (SHH) pathway is implicated in the etiology of the most common human cancer in Caucasians, the basal cell carcinoma (BCC). Mutations in the receptor of SHH, the patched gene, have been characterized in sporadic BCCs as well as thos