Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sophie Claydon"'
Publikováno v:
F1000Research, Vol 8 (2019)
Actin polymerization is essential for cells to migrate, as well as for various cell biological processes such as cytokinesis and vesicle traffic. This brief review describes the mechanisms underlying its different roles and recent advances in our und
Externí odkaz:
https://doaj.org/article/b7c08d3186d04695a09767d9efe3bfa0
Autor:
Simona Buracco, Shashi Singh, Sophie Claydon, Peggy Paschke, Luke Tweedy, Jamie Whitelaw, Lynn McGarry, Peter A. Thomason, Robert H. Insall
Cell migration requires the constant modification of cellular shape by reorganization of the actin cytoskeleton. The pentameric Scar/WAVE regulatory complex (WRC) is the main catalyst of pseudopod and lamellipodium formation. Its actin nucleation act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f48453d52e11a3f6ba0b96bfcf8bdf9
https://doi.org/10.1101/2022.05.14.491902
https://doi.org/10.1101/2022.05.14.491902
Autor:
Stuart Francis, Daniel Croft, Alexander W. Schüttelkopf, Charles Parry, Angelo Pugliese, Ken Cameron, Sophie Claydon, Martin Drysdale, Claire Gardner, Andrea Gohlke, Gillian Goodwin, Christopher H. Gray, Jennifer Konczal, Laura McDonald, Mokdad Mezna, Andrew Pannifer, Nikki R. Paul, Laura Machesky, Heather McKinnon, Justin Bower
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Graphical abstract
Fascin is an actin binding and bundling protein that is not expressed in normal epithelial tissues but overexpressed in a variety of invasive epithelial tumors. It has a critical role in cancer cell metastasis by promoting cel
Fascin is an actin binding and bundling protein that is not expressed in normal epithelial tissues but overexpressed in a variety of invasive epithelial tumors. It has a critical role in cancer cell metastasis by promoting cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e186e38a41872ad9934b9ce7197280
https://doi.org/10.1016/j.bmcl.2019.01.035
https://doi.org/10.1016/j.bmcl.2019.01.035