Výsledky vyhledávání - "Sophie Capaert"

Recombinant staphylokinase variants with reduced antigenicity due to elimination of B-lymphocyte epitopes

Autor: Sophie Capaert, Stephane Heymans, Frans De Cock, Eddy Demarsin, Desire Collen, Yves Laroche

Publikováno v: Blood. 96:1425-1432

Site directed mutagenesis (350 variants) of recombinant staphylokinase (SakSTAR), a potent fibrin-selective thrombolytic agent, was undertaken in order to reduce its antigenicity while maintaining its potency. Variants with K35A, (ie, Lys[K] in posit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bfc78b6c80e03a4719355b50167f29
https://doi.org/10.1182/blood.v96.4.1425.h8001425_1425_1432

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