Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sophie Callies"'
Autor:
Saroj Vadhan-Raj, Rafat Abonour, Jonathan W. Goldman, David A. Smith, Christopher A. Slapak, Robert L. Ilaria, Ramon V. Tiu, Xuejing Wang, Sophie Callies, Joanne Cox, Jay L. Tuttle, Yiu-Keung Lau, Eric J. Roeland
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background Hepcidin plays a central role in iron homeostasis and erythropoiesis. Neutralizing hepcidin with a monoclonal antibody (mAb) may prevent ferroportin internalization, restore iron efflux from cells, and allow transferrin-mediated i
Externí odkaz:
https://doaj.org/article/d0975f366e274a1ea6ec2e25ee746386
Autor:
Kazuhiko Nakagawa, Edward B. Garon, Ling Gao, Sophie Callies, Annamaria Zimmermann, Richard Walgren, Carla Visseren-Grul, Martin Reck
Publikováno v:
Cancer chemotherapy and pharmacology, vol 90, iss 2
Purpose In RELAY, ramucirumab plus erlotinib (RAM + ERL) improved progression-free survival (PFS) in patients with untreated, metastatic, EGFR-mutated, non-small cell lung cancer (NSCLC). Here, we present the exposure–response relationship of RAM f
Autor:
Andrew X. Zhu, Elena Gonzalez-Gugel, Ryan C. Widau, Paolo Abada, Chunxiao Wang, Louise M. McGrath, Sophie Callies, Masafumi Ikeda, Peter R. Galle, Masatoshi Kudo, Richard S. Finn, Augusto Villanueva, Amit G. Singal, Josep M. Llovet
Supplementary Table from Prognostic and Predictive Factors in Patients with Advanced HCC and Elevated Alpha-Fetoprotein Treated with Ramucirumab in Two Randomized Phase III Trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042489455dee271c751f57309d7e387b
https://doi.org/10.1158/1078-0432.22486710
https://doi.org/10.1158/1078-0432.22486710
Autor:
Kathleen N. Moore, Volker Wacheck, Aaron Fink, Enaksha Wickremsinhe, Ricardo Martinez, Ji Lin, Sophie Callies, Shubham Pant, Todd M. Bauer, David M. Hyman, Anna M. Varghese, Johanna C. Bendell
Figures S1 to S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571e2eb48394fa5ab712daab80ae4688
https://doi.org/10.1158/1078-0432.22470285
https://doi.org/10.1158/1078-0432.22470285
Autor:
Patricia Price, Azeem Saleem, Julian Matthews, Johann S. de Bono, Peter J. McHugh, Anna L Olsen, Christopher Slapak, Michael Burgess, Sunil Kadam, Valérie André, Sophie Callies, Michael Lahn, Joanna Davies, Malcolm Ranson, Denis C. Talbot
Purpose: Enhanced tumor cell survival through expression of inhibitors of apoptosis (IAP) is a hallmark of cancer. Survivin, an IAP absent from most normal tissues, is overexpressed in many malignancies and associated with a poorer prognosis. We repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b2a8492d795bdb92f964c057eacca0
https://doi.org/10.1158/1078-0432.c.6519461
https://doi.org/10.1158/1078-0432.c.6519461
Autor:
Kathleen N. Moore, Volker Wacheck, Aaron Fink, Enaksha Wickremsinhe, Ricardo Martinez, Ji Lin, Sophie Callies, Shubham Pant, Todd M. Bauer, David M. Hyman, Anna M. Varghese, Johanna C. Bendell
Purpose: The PI3K/mTOR pathway is frequently aberrated in cancer. LY3023414 is a potent and selective ATP-competitive inhibitor of class I PI3K isoforms, mTOR, and DNA-PK. Here we report the dose-escalation results of the first-in-human phase I study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6d6079d900566967225fb04757e7d4
https://doi.org/10.1158/1078-0432.c.6527502
https://doi.org/10.1158/1078-0432.c.6527502
Autor:
Johanna C. Bendell, Boris Kin Lin, Sophie Callies, Anna M. Szpurka, Gregory P. Donoho, Volker Wacheck, Wei Zhang, Susan C. Guba, Paul R. Sieber, Neal D. Shore, Costantine Albany, Ian D. Schnadig, David S. Morris, Oscar B. Goodman, Bryan A. Mehlhaff, Jennifer L. Cultrera, Sunil Babu, Ivor J. Percent, Christopher J. Sweeney
Supplementary Figure from Phase Ib/II Study of Enzalutamide with Samotolisib (LY3023414) or Placebo in Patients with Metastatic Castration-Resistant Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224daf568721c80e465b0dae93e74292
https://doi.org/10.1158/1078-0432.22482390.v1
https://doi.org/10.1158/1078-0432.22482390.v1
Autor:
George Simon, Mayer Fishman, Funda Meric-Bernstam, Timothy R. Holzer, Aejaz Nasir, Sunil K. Kadam, Valérie André, Sophie Callies, Les Brail, Aung Naing, Jennifer Wheler, Yun Oh, Razelle Kurzrock, David S. Hong
CCR Translation for This Article from A Phase 1 Dose Escalation, Pharmacokinetic, and Pharmacodynamic Evaluation of eIF-4E Antisense Oligonucleotide LY2275796 in Patients with Advanced Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e3a97d95d71f68d35418f84b3673e1
https://doi.org/10.1158/1078-0432.22443176.v1
https://doi.org/10.1158/1078-0432.22443176.v1
Autor:
Kathleen N. Moore, Volker Wacheck, Aaron Fink, Enaksha Wickremsinhe, Ricardo Martinez, Ji Lin, Sophie Callies, Shubham Pant, Todd M. Bauer, David M. Hyman, Anna M. Varghese, Johanna C. Bendell
Supplemental Figures: S1-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2d4a75a16d8328b66b62428f0255ec
https://doi.org/10.1158/1078-0432.22470288.v1
https://doi.org/10.1158/1078-0432.22470288.v1
Autor:
Andrew X. Zhu, Elena Gonzalez-Gugel, Ryan C. Widau, Paolo Abada, Chunxiao Wang, Louise M. McGrath, Sophie Callies, Masafumi Ikeda, Peter R. Galle, Masatoshi Kudo, Richard S. Finn, Augusto Villanueva, Amit G. Singal, Josep M. Llovet
Supplementary Figure from Prognostic and Predictive Factors in Patients with Advanced HCC and Elevated Alpha-Fetoprotein Treated with Ramucirumab in Two Randomized Phase III Trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270a4ffc8a1b7dc861694e9b3b0f1f24
https://doi.org/10.1158/1078-0432.22486725.v1
https://doi.org/10.1158/1078-0432.22486725.v1