Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sophie C. Binder"'
Autor:
Lisa D. J. Schiffelers, Yonas M. Tesfamariam, Lea-Marie Jenster, Stefan Diehl, Sophie C. Binder, Sabine Normann, Jonathan Mayr, Steffen Pritzl, Elena Hagelauer, Anja Kopp, Assaf Alon, Matthias Geyer, Hidde L. Ploegh, Florian I. Schmidt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Inflammasome activation results in the cleavage of gasdermin D (GSDMD) by pro-inflammatory caspases. The N-terminal domains (GSDMDNT) oligomerize and assemble pores penetrating the target membrane. As methods to study pore formation in livin
Externí odkaz:
https://doaj.org/article/c6aca2be08454fe89a514abe6567e4f2
Autor:
Robert Düster, Kanchan Anand, Sophie C. Binder, Maximilian Schmitz, Karl Gatterdam, Robert P. Fisher, Matthias Geyer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cyclin-dependent kinase 7 (Cdk7) is required in cell-cycle and transcriptional regulation owing to its function as both a CDK-activating kinase (CAK) and part of transcription factor TFIIH. Cdk7 forms active complexes by associating with Cyc
Externí odkaz:
https://doaj.org/article/d4ad56dbbd94425f85a4265319b18646
Autor:
Lisa D.J. Schiffelers, Sabine Normann, Sophie C. Binder, Elena Hagelauer, Anja Kopp, Assaf Alon, Matthias Geyer, Hidde L. Ploegh, Florian I. Schmidt
Activation of various inflammasomes converges on the cleavage of gasdermin D (GSDMD) by pro-inflammatory caspases, followed by oligomerization of the N-terminal domain (GSDMDNT) and the assembly of pores penetrating target membranes. Yet, it remained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373e5086a2888f1279605f5ddb9e3c44
https://doi.org/10.1101/2023.04.20.537718
https://doi.org/10.1101/2023.04.20.537718
