Výsledky vyhledávání - "Sophie Brinster"

Akademický článek

Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials

Autor: Claire Morvan, David Halpern, Gérald Kénanian, Constantin Hays, Jamila Anba-Mondoloni, Sophie Brinster, Sean Kennedy, Patrick Trieu-Cuot, Claire Poyart, Gilles Lamberet, Karine Gloux, Alexandra Gruss

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

The bacterial pathway for fatty acid biosynthesis, FASII, is a target for development of new anti-staphylococcal drugs. Here, Morvan et al. show that exogenous fatty acids can favour the emergence of staphylococcal strains displaying resistance to mu

Externí odkaz: https://doaj.org/article/e8d21997597244098908c235c4491102

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Type II fatty acid synthesis pathway and cyclopropane ring formation are dispensable during Enterococcus faecalis systemic infection

Autor: Alexandra Gruss, Laurence du Merle, Karine Gloux, Gilles Lamberet, Agnès Fouet, Constantin Hays, Claire Poyart, Clara Lambert, Sophie Brinster

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, 2021, 203 (20), pp.e0022121. ⟨10.1128/JB.00221-21⟩
J Bacteriol
Journal of Bacteriology, American Society for Microbiology, 2021, 203 (20), pp.e0022121. ⟨10.1128/JB.00221-21⟩

Enterococcus faecalis, a multiple antibiotic-resistant Gram-positive bacterium, has emerged as a serious nosocomial pathogen. Here, we used a genetic approach to characterize the strategies used by E. faecalis to fulfill its requirements for endogeno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf009f7c0ec71a98559809bc0814e41c
https://hal.science/hal-03408405/file/JB00221-21_Merged_PDF.pdf

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Akademický článek

The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus.

Autor: Arnaud Firon, Asmaa Tazi, Violette Da Cunha, Sophie Brinster, Elisabeth Sauvage, Shaynoor Dramsi, Douglas T Golenbock, Philippe Glaser, Claire Poyart, Patrick Trieu-Cuot

Publikováno v: PLoS Pathogens, Vol 9, Iss 2, p e1003179 (2013)

Group B Streptococcus (GBS), a common commensal of the female genital tract, is the leading cause of invasive infections in neonates. Expression of major GBS virulence factors, such as the hemolysin operon cyl, is regulated directly at the transcript

Externí odkaz: https://doaj.org/article/ce80e8fb70d14066acbdafaf34deea62

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Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials

Autor: Karine Gloux, Sophie Brinster, Constantin Hays, Gilles Lamberet, Gérald Kénanian, Jamila Anba-Mondoloni, Sean Kennedy, Alexandra Gruss, Claire Poyart, David Halpern, Patrick Trieu-Cuot, Claire Morvan

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, pp.12944
Nature Communications, 2016, 7, pp.12944. ⟨10.1038/ncomms12944⟩
Nature Communications, Nature Publishing Group, 2016, 7, pp.12944. ⟨10.1038/ncomms12944⟩
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications (7), 12944. (2016)

The bacterial pathway for fatty acid biosynthesis, FASII, is a target for development of new anti-staphylococcal drugs. This strategy is based on previous reports indicating that self-synthesized fatty acids appear to be indispensable for Staphylococ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bfb325f2f5a5f51ca74848f78e9aba
https://hal-pasteur.archives-ouvertes.fr/pasteur-01385175/file/ncomms12944.pdf

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Enterococcal Leucine-Rich Repeat-Containing Protein Involved in Virulence and Host Inflammatory Response

Autor: Samira Makhzami, Adriana Alberti, Sophie Brinster, Hélène Bierne, Pascale Serror, Maurizio Sanguinetti, Brunella Posteraro

Publikováno v: Infection and Immunity
Infection and Immunity, 2007, 75 (9), pp.4463-4471. ⟨10.1128/IAI.00279-07⟩
Infection and Immunity, American Society for Microbiology, 2007, 75 (9), pp.4463-4471. ⟨10.1128/IAI.00279-07⟩

Enterococcus faecalis is an important nosocomial pathogen associated with high morbidity and mortality for patients who are immunocompromised or who have severe underlying diseases. The E. faecalis genome encodes numerous surface-exposed proteins tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915f18dbcd6c0492df4ed15b9302e97d
https://doi.org/10.1128/iai.00279-07

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The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus

Autor: Sophie Brinster, Claire Poyart, Arnaud Firon, Asmaa Tazi, Shaynoor Dramsi, Patrick Trieu-Cuot, Philippe Glaser, Elisabeth Sauvage, Douglas T. Golenbock, Violette Da Cunha

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2013, 9 (2), pp.e1003179. ⟨10.1371/journal.ppat.1003179⟩
PLoS Pathogens, Public Library of Science, 2013, 9 (2), pp.e1003179. ⟨10.1371/journal.ppat.1003179⟩
PLoS Pathogens, Vol 9, Iss 2, p e1003179 (2013)
PLoS Pathogens, Public Library of Science, 2013, 9 (2), pp.e1003179. 〈10.1371/journal.ppat.1003179〉

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448e00d0a86aa715dbfc806edb6ad7fe
https://hal-pasteur.archives-ouvertes.fr/pasteur-01300159/file/journal.ppat.1003179.pdf

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Enterococcal Rgg-Like Regulator ElrR Activates Expression of the elrA Operon

Autor: Francis Repoila, Maurizio Sanguinetti, Riccardo Torelli, Romain Dumoulin, Naima G. Cortes-Perez, Brunella Posteraro, Philippe Duhutrel, Sophie Brinster, Pascale Serror, Stéphane Gaubert

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2013, 195 (13), pp.3073-3083. ⟨10.1128/JB.00121-13⟩

The Enterococcus faecalis leucine-rich protein ElrA promotes virulence by stimulating bacterial persistence in macrophages and production of the interleukin-6 (IL-6) cytokine. The ElrA protein is encoded within an operon that is poorly expressed unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d4b49d9301cab94559ff8d4d452afc
https://hal.archives-ouvertes.fr/hal-01001022

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Development of an Efficient In Vivo System (P-junc-TpaseIS(1223)) for Random Transposon Mutagenesis of Lactobacillus casei

Autor: Hélène Licandro-Seraut, Pascale Serror, Sophie Brinster, Jean-François Cavin, Emmanuelle Maguin, Maarten van de Guchte, Hélène Scornec, Philippe J. Sansonetti

Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2012, 78 (15), pp.5417-5423. ⟨10.1128/AEM.00531-12⟩
Applied and Environmental Microbiology, American Society for Microbiology, 2012, 78 (15), pp.5417-5423. 〈10.1128/AEM.00531-12〉
Applied and Environmental Microbiology, 2012, 78 (15), pp.5417-5423. ⟨10.1128/AEM.00531-12⟩

The random transposon mutagenesis system P junc -TpaseIS 1223 is composed of plasmids pVI129, expressing IS 1223 transposase, and pVI110, a suicide transposon plasmid carrying the P junc sequence, the substrate of the IS 1223 transposase. This system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14f18597f4129d3b250a8c9b7f42b57
https://hal.archives-ouvertes.fr/hal-01004149

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An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach

Autor: Philippe Bessières, Philippe Noirot, Vincent Fromion, Elodie Marchadier, Marie-Françoise Noirot-Gros, Sophie Brinster, Rut Carballido-López, Peggy Mervelet, Céline Fabret

Publikováno v: Proteomics
Proteomics, Wiley-VCH Verlag, 2011, 11 (15), pp.2981-2991. ⟨10.1002/pmic.201000791⟩
Proteomics, 2011, 11 (15), pp.2981-2991. ⟨10.1002/pmic.201000791⟩
Proteomics 15 (11), 2981-2991. (2011)

We have generated a protein-protein interaction network in Bacillus subtilis focused on several essential cellular processes such as cell division, cell responses to various stresses, the bacterial cytoskeleton, DNA replication and chromosome mainten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dc4be42d3c8695c227b35bce37b446
https://hal.archives-ouvertes.fr/hal-01000282

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Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

Autor: Claire Poyart, Sophie Brinster, Gilles Lamberet, Alexandra Gruss, Bart Staels, Patrick Trieu-Cuot

Publikováno v: Nature
Nature, Nature Publishing Group, 2009, 458 (7234), pp.83-6. 〈10.1038/nature07772〉
Nature, 2009, 458 (7234), pp.83-6. ⟨10.1038/nature07772⟩
Nature, Nature Publishing Group, 2009, 458 (7234), pp.83-6. ⟨10.1038/nature07772⟩

The type II fatty acid synthesis (FASII) pathway has been suggested to be a promising antimicrobial target, and the antibiotics platensimycin and platencin that target this pathway are claimed to be potentially effective against multiresistant Gram-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fc057f3872d75daf10185ac939c067
https://hal-pasteur.archives-ouvertes.fr/pasteur-00366166

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