Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sophie Braga-Lagache"'
Autor:
Joachim Müller, Carling Schlange, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache, Richard K. Haynes, Andrew Hemphill
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 21, Iss , Pp 1-12 (2023)
The sesquiterpene lactone artemisinin and its amino-artemisinin derivatives artemiside (GC008) and artemisone (GC003) are potent antimalarials. The mode of action of artemisinins against Plasmodium sp is popularly ascribed to 'activation' of the pero
Externí odkaz:
https://doaj.org/article/ab6fe9874f28493880edaf6ef7fc235c
Autor:
Mahmoud Hallal, Sophie Braga-Lagache, Jovana Jankovic, Cedric Simillion, Rémy Bruggmann, Anne-Christine Uldry, Ramanjaneyulu Allam, Manfred Heller, Nicolas Bonadies
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Despite the introduction of targeted therapies, most patients with myeloid malignancies will not be cured and progress. Genomics is useful to elucidate the mutational landscape but remains limited in the prediction of therapeutic
Externí odkaz:
https://doaj.org/article/5de865060f1f4c709febcf28371fa294
Autor:
Joachim Müller, Ghalia Boubaker, Dennis Imhof, Kai Hänggeli, Noé Haudenschild, Anne-Christine Uldry, Sophie Braga-Lagache, Manfred Heller, Luis-Miguel Ortega-Mora, Andrew Hemphill
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2675 (2022)
Leucinostatins are antimicrobial peptides with a broad range of activities against infectious agents as well as mammalian cells. The leucinostatin-derivative peptide ZHAWOC_6027 (peptide 6027) was tested in vitro and in vivo for activity against the
Externí odkaz:
https://doaj.org/article/2ba88df426664e6781b75855c7acd0f4
Autor:
Magdalena A T Brunner, Silvia Rüfenacht, Anina Bauer, Susanne Erpel, Natasha Buchs, Sophie Braga-Lagache, Manfred Heller, Tosso Leeb, Vidhya Jagannathan, Dominique J Wiener, Monika M Welle
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212645 (2019)
Bald thigh syndrome is a common hair loss disorder in sighthounds. Numerous possible causes, including environmental conditions, trauma, stress, endocrinopathies and genetic components have been proposed, but only endocrinopathies have been ruled out
Externí odkaz:
https://doaj.org/article/82d45843f35445a3b21c6419580eb622
Autor:
Pablo Winzer, Joachim Müller, Dennis Imhof, Dominic Ritler, Anne-Christine Uldry, Sophie Braga-Lagache, Manfred Heller, Kayode K. Ojo, Wesley C. Van Voorhis, Luis-Miguel Ortega-Mora, Andrew Hemphill
Publikováno v:
Microorganisms, Vol 8, Iss 6, p 801 (2020)
Background: the apicomplexan parasite Neospora caninum causes important reproductive problems in farm animals, most notably in cattle. After infection via oocysts or tissue cysts, rapidly dividing tachyzoites infect various tissues and organs, and in
Externí odkaz:
https://doaj.org/article/7d4bc91b2ccf4609b552e30d5cf67209
Autor:
Natasha Buchs, Sophie Braga-Lagache, Anne-Christine Uldry, Justine Brodard, Christophe Debonneville, Jean-Sébastien Reynard, Manfred Heller
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Grapevine red blotch is a recently identified viral disease that was first recognized in the Napa Valley of California. Infected plants showed foliar symptoms similar to leafroll, another grapevine viral disease, on vines testing negative for known g
Externí odkaz:
https://doaj.org/article/42494313aca846d7a8bd0c8a38145e5c
Autor:
Karin Stettler, Xiaoming Li, Björn Sandrock, Sophie Braga-Lagache, Manfred Heller, Lutz Dümbgen, Beat Suter
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 1, Pp 81-91 (2015)
XPD functions in transcription, DNA repair and in cell cycle control. Mutations in human XPD (also known as ERCC2) mainly cause three clinical phenotypes: xeroderma pigmentosum (XP), Cockayne syndrome (XP/CS) and trichothiodystrophy (TTD), and only X
Externí odkaz:
https://doaj.org/article/ae1f7c724ef5423c8ee8bd93a0ecd6bf
Autor:
Stefan Zahnd, Sophie Braga-Lagache, Natasha Buchs, Alessandro Lugli, Heather Dawson, Manfred Heller, Inti Zlobec
Publikováno v:
Journal of Pathology Informatics, Vol 10, Iss 1, Pp 40-40 (2019)
Background: Biomarkers in colorectal cancer are scarce, especially for patients with Stage 2 disease. The aim of our study was to identify potential prognostic biomarkers from colorectal cancers using a novel combination of approaches, whereby digita
Externí odkaz:
https://doaj.org/article/54b8393119ae47bbabab0fb0f1554882
Autor:
Kornél Nagy, Birgit Holst, Javier Santos, Martin Kussmann, Laurent Sagalowicz, Simone Acquistapace, Julie Moulin, Maurice Beaumont, Juan Ramón Malagelada, Fernando Azpiroz, Valentí Puig-Divi, Laura Ramos, Sophie Braga-Lagache, Marie-Claude Courtet-Compondu, Beatriz Lobo, Gary Williamson
Publikováno v:
CHIMIA, Vol 68, Iss 3 (2014)
We determined the bioavailability of vitamin E from self-assembly structures in patients with diagnosed chronic pancreas insufficiency. Vitamin E solubilized in dispersed inverted bicontinuous cubic phase and in micellar formulation was delivered dir
Externí odkaz:
https://doaj.org/article/0adadfc44cad4e72a1e242a6d0b09f49
Autor:
Boubaker, Kai Pascal Alexander Hänggeli, Andrew Hemphill, Norbert Müller, Manfred Heller, Anne-Christine Uldry, Sophie Braga-Lagache, Joachim Müller, Ghalia
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10454
In T. gondii, as well as in other model organisms, gene knock-out using CRISPR-Cas9 is a suitable tool to identify the role of specific genes. The general consensus implies that only the gene of interest is affected by the knock-out. Is this really t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::64c9d9afa100bc0b2dbb0010ac8f2e80