Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sophie Black"'
Autor:
Krishnapriya Hari, Ana M. Lucas-Osma, Krista Metz, Shihao Lin, Noah Pardell, David A. Roszko, Sophie Black, Anna Minarik, Rahul Singla, Marilee J. Stephens, Robert A. Pearce, Karim Fouad, Kelvin E. Jones, Monica A. Gorassini, Keith K. Fenrich, Yaqing Li, David J. Bennett
Publikováno v:
Nat Neurosci
Movement and posture depend on sensory feedback that is regulated by specialized GABAergic neurons (GAD2+) that form axo-axonic contacts onto myelinated proprioceptive sensory axons and are thought to be inhibitory. However, we report here that activ
Autor:
Shihao Lin, Krishnapriya Hari, Ana M. Lucas-Osma, Sophie Black, Aysan Khatmi, Karim Fouad, Monica A. Gorassini, Yaqing Li, Keith K. Fenrich, David J. Bennett
When a muscle is stretched it not only responds with a reflex, but the sensory afferent feedback also depolarizes many afferents throughout the spinal cord (termed primary afferent depolarization, PAD), readying the whole limb for further disturbance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f996ab5fe4e275d567eb843c73fb0141
https://doi.org/10.1101/2022.07.04.498712
https://doi.org/10.1101/2022.07.04.498712
Autor:
Jenny Liao, J. Gregory Cairncross, Jacob Willms, Alice L. Yuan, Haley Pedersen, Michael D. Blough, Lori Maxwell, Mathieu Meode, Melanie Tan, Elizabeth A. Bering, Sophie Black
Publikováno v:
Journal of Neuro-Oncology. 148:463-472
Temozolomide (TMZ) is a life prolonging DNA alkylating agent active against glioblastomas (GBM) in which the O6-methylguanine-DNA methyltransferase (MGMT) gene is silenced by promoter methylation. Unfortunately acquired TMZ resistance severely underm
Autor:
Ana M. Lucas-Osma, Yaqing Li, Marilee J. Stephens, Sophie Black, Andrew H. Ahn, Keith K. Fenrich, Katie Murray, David J. Bennett, Karim Fouad, Charles J. Heckman, Shihao Lin
Publikováno v:
J Neurophysiol
The monosynaptic stretch reflex (MSR) plays an important role in feedback control of movement and posture but can also lead to unstable oscillations associated with tremor and clonus, especially when increased with spinal cord injury (SCI). To contro
Autor:
Ana M. Lucas-Osma, Rahul Singla, David J. Bennett, Sophie Black, Yaqing Li, Keith K. Fenrich, Shihao Lin, Karim Fouad
Publikováno v:
Journal of Neurophysiology. 120:2953-2974
Activation of GABAA receptors on sensory axons produces a primary afferent depolarization (PAD) that modulates sensory transmission in the spinal cord. While axoaxonic synaptic contacts of GABAergic interneurons onto afferent terminals have been exte
Autor:
Marilee J. Stephens, Leo Sanelli, Keith K. Fenrich, Mischa V Bandet, Ana M. Lucas-Osma, Yaqing Li, Romana Vavrek, Antonio Fabio Di Narzo, Ian R. Winship, Sophie Black, Stella Dracheva, David J. Bennett, Karim Fouad
Publikováno v:
Nature medicine
Blood vessels in the central nervous system (CNS) are controlled by neuronal activity. For example, widespread vessel constriction (vessel tone) is induced by brainstem neurons that release the monoamines serotonin and noradrenaline, and local vessel
Publikováno v:
Progress in Disaster Science, Vol 21, Iss , Pp 100315- (2024)
Citizen priorities, needs, and rights have been moving to the centre of ‘good’ risk management and governance in theory, but what is their role in practice? The disastrous impacts of the flooding event across western Europe in 2021 highlighted ma
Externí odkaz:
https://doaj.org/article/bdc20c24defe48688b7cc186eb5fb007
Autor:
Ana M, Lucas-Osma, Yaqing, Li, Shihao, Lin, Sophie, Black, Rahul, Singla, Karim, Fouad, Keith K, Fenrich, David J, Bennett
Publikováno v:
Journal of neurophysiology. 120(6)
Activation of GABA(A) receptors on sensory axons produces a primary afferent depolarization (PAD) that modulates sensory transmission in the spinal cord. While axoaxonic synaptic contacts of GABAergic interneurons onto afferent terminals have been ex
Autor:
Neil E Hill, Nick S Oliver, Wei Yang, Christine Shi, Chioma Izzi-Engbeaya, Walter Distaso, Anjali Amin, Oluwagbemiga Idowu, Julia S Kenkre, Ronak J Shah, Evelina Woin, Nael Alavi, Hala Bedri, Niamh Brady, Sophie Blackburn, Martina Leczycka, Sanya Patel, Elizaveta Sokol, Edward Toke-Bjolgerud, Ambreen Qayum, Mariana Abdel-Malek, David C D Hope, Vasiliki Bravis, Tricia M Tan, Victoria Salem
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction Patients with diabetes mellitus admitted to hospital with COVID-19 have poorer outcomes. However, the drivers of poorer outcomes are not fully elucidated. We performed detailed characterization of patients with COVID-19 to determine the
Externí odkaz:
https://doaj.org/article/7eb1ab04c8e4484f83b7fe832907e545