Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sophie Bergmann"'
Autor:
Timo N. Kohler, Joachim De Jonghe, Anna L. Ellermann, Ayaka Yanagida, Michael Herger, Erin M. Slatery, Antonia Weberling, Clara Munger, Katrin Fischer, Carla Mulas, Alex Winkel, Connor Ross, Sophie Bergmann, Kristian Franze, Kevin Chalut, Jennifer Nichols, Thorsten E. Boroviak, Florian Hollfelder
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Biomechanical cues are instrumental in guiding embryonic development and cell differentiation. Understanding how these physical stimuli translate into transcriptional programs will provide insight into mechanisms underlying mammalian pre-imp
Externí odkaz:
https://doaj.org/article/19d37a4e6ae24ca8b14f83a6a064a669
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation, but understanding of the dynamics of metabolic regulation in the postimplantation embryo in vivo remains elusive. Here the authors compile single-cell embryo profiling data i
Externí odkaz:
https://doaj.org/article/b86c0c5c463f4a179d9f465618188a37
Autor:
Sophie Bergmann, Magdalena Schindler, Clara Munger, Christopher A. Penfold, Thorsten E. Boroviak
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Bergmann et al. discuss the construction of synthetic uteri to model the earliest stages of human embryogenesis and associated pathologies. They highlight the constituent components from which a synthetic uterus may be engineered, propose a modular a
Externí odkaz:
https://doaj.org/article/54d4617772f1427b91d1778fca25aeb6
Autor:
Aracely Castillo-Venzor, Christopher A Penfold, Michael D Morgan, Walfred WC Tang, Toshihiro Kobayashi, Frederick CK Wong, Sophie Bergmann, Erin Slatery, Thorsten E Boroviak, John C Marioni, M Azim Surani
Publikováno v:
Life Science Alliance. 6:e202201706
Human germline-soma segregation occurs during weeks 2-3 in gastrulating embryos. While direct studies are hindered, here we investigate the dynamics of human primordial germ cell (PGCs) specification using in vitro models with temporally resolved sin
Autor:
Timo N. Kohler, Joachim De Jonghe, Anna L. Ellerman, Ayaka Yanagida, Michael Herger, Erin M. Slatery, Katrin Fischer, Carla Mulas, Alex Winkel, Connor Ross, Sophie Bergmann, Kristian Franze, Kevin Chalut, Jennifer Nichols, Thorsten E. Boroviak, Florian Hollfelder
Biomechanical cues are instrumental in guiding embryonic development and cell differentiation. Understanding how these physical stimuli translate into transcriptional programs could provide insight into mechanisms underlying mammalian pre-implantatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c741f38e1670e171ebf6a355c63c9f57
https://doi.org/10.1101/2022.03.13.484158
https://doi.org/10.1101/2022.03.13.484158
Autor:
Sophie Bergmann, Christopher A. Penfold, Erin Slatery, Dylan Siriwardena, Charis Drummer, Stephen Clark, Stanley E. Strawbridge, Keiko Kishimoto, Alice Vickers, Mukul Tewary, Timo N. Kohler, Florian Hollfelder, Wolf Reik, Erika Sasaki, Rüdiger Behr, Thorsten E. Boroviak
Publikováno v:
Nature
Gastrulation controls the emergence of cellular diversity and axis patterning in the early embryo. In mammals, this transformation is orchestrated by dynamic signalling centres at the interface of embryonic and extraembryonic tissues1-3. Elucidating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c865ba8270fb8211dd8935ed4b1598
Autor:
Clara Munger, Timo N. Kohler, Erin Slatery, Anna L. Ellermann, Sophie Bergmann, Christopher A. Penfold, Ioakeim Ampartzidis, Yutong Chen, Florian Hollfelder, Thorsten E. Boroviak
Publikováno v:
Development (Cambridge, England). 149(20)
Funder: Wellcome Trust; Id: http://dx.doi.org/10.13039/100010269
Funder: Royal Society; Id: http://dx.doi.org/10.13039/501100000288
Funder: AstraZeneca; Id: http://dx.doi.org/10.13039/100004325
Funder: University of Cambridge; Id: http
Funder: Royal Society; Id: http://dx.doi.org/10.13039/501100000288
Funder: AstraZeneca; Id: http://dx.doi.org/10.13039/100004325
Funder: University of Cambridge; Id: http
Autor:
Christopher A. Penfold, Magdalena Schindler, Sophie Bergmann, Clara Munger, Thorsten Boroviak
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
The uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term births. However, in vitro models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792daaf42da3a53a69bec20610adf8ff
https://www.repository.cam.ac.uk/handle/1810/326071
https://www.repository.cam.ac.uk/handle/1810/326071
Autor:
Thomas Rosenau, Markus Bacher, Lars Gille, Sritama De Sarkar, Gerald Geroldinger, Mitali Chatterjee, Katrin Staniek, Sophie Bergmann, Ramón Scull, Matthias Tonner, Lianet Monzote
Publikováno v:
Phytotherapy Research. 32:1729-1740
The antileishmanial activity of the essential oil (EO) from Chenopodium ambrosioides L. has been demonstrated in vitro and in animal models, attributed to the major components of the EO. This study focused on the effects of the three major EO compoun
Autor:
Marie Sophie Narzt, Erwin Tschachler, Gabor G. Kovacs, Günther Rauter, Florian Gruber, Supawadee Sukseree, Lajos László, Leopold Eckhart, Kinga Molnár, Romana Höftberger, Thomas Birngruber, Lionel Larue, Ionela Mariana Nagelreiter, Sophie Bergmann
Publikováno v:
Molecular Neurobiology
Defects in autophagy and the resulting deposition of protein aggregates have been implicated in aging and neurodegenerative diseases. While gene targeting in the mouse has facilitated the characterization of these processes in different types of neur