Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sophie Bellone"'
Autor:
William S. Powell, Chantal Cossette, Seongjin Kim, Joshua Rokach, Gue-Jae Lee, Sinead E Walsh, Sophie Bellone, John A. Lawson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 320:173-179
Prostaglandin (PG) D2 acts through both the DP(1) receptor, which is coupled to adenylyl cyclase, and the DP2 receptor (chemoattractant receptor-homologous molecule expressed on Th2 cells), which is present on eosinophils, basophils, and Th2 cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41de1baced8ad1076f260119a47e9ca1
https://doi.org/10.1124/jpet.106.111062
https://doi.org/10.1124/jpet.106.111062
Autor:
John A. Lawson, Garret A. FitzGerald, Sophie Bellone, William S. Powell, Domenico Praticò, Seongjin Kim, Joshua Rokach
Publikováno v:
Chemistry and Physics of Lipids. 128:35-56
Isoprostanes (iP’s), a new class of natural products isomeric with prostaglandins, are formed as the result of free radical oxygenation of polyunsaturated fatty acids. We have identified these iP’s and developed analytical methodology to measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949cb955eda665cd74a6839d177064ef
https://doi.org/10.1016/j.chemphyslip.2003.09.011
https://doi.org/10.1016/j.chemphyslip.2003.09.011
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(7)
The first total synthesis of 15R-PGD2 3 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE2. 15R-PGD2, a potential DP2 receptor agonist, could be an important novel tool for defining the role of this rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd1a6f02d1fcb0b9a567b41eadba70b
https://pubmed.ncbi.nlm.nih.gov/15780624
https://pubmed.ncbi.nlm.nih.gov/15780624