Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Sophie Bachellier"'
β-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall
Autor:
Clara Bekirian, Isabel Valsecchi, Sophie Bachellier-Bassi, Cyril Scandola, J Inaki Guijarro, Murielle Chauvel, Thierry Mourer, Neil AR Gow, Vishu Kumar Aimanianda, Christophe d'Enfert, Thierry Fontaine
Publikováno v:
eLife, Vol 13 (2024)
The cell wall of human fungal pathogens plays critical roles as an architectural scaffold and as a target and modulator of the host immune response. Although the cell wall of the pathogenic yeast Candida albicans is intensively studied, one of the ma
Externí odkaz:
https://doaj.org/article/a4fc7606e52d4717a6ada9f460279c02
Autor:
Laxmi Shanker Rai, Murielle Chauvel, Hiram Sanchez, Lasse van Wijlick, Corinne Maufrais, Thomas Cokelaer, Natacha Sertour, Mélanie Legrand, Kaustuv Sanyal, David R Andes, Sophie Bachellier-Bassi, Christophe d'Enfert
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002693 (2024)
Candida albicans is a commensal of the human microbiota that can form biofilms on implanted medical devices. These biofilms are tolerant to antifungals and to the host immune system. To identify novel genes modulating C. albicans biofilm formation, w
Externí odkaz:
https://doaj.org/article/950f30e96bf34aa18748985f1e9630d6
Autor:
Mayssa Gnaien, Corinne Maufrais, Yasmine Rebai, Aicha Kallel, Laurence Ma, Samia Hamouda, Fatma Khalsi, Khaoula Meftah, Hanen Smaoui, Monia Khemiri, Sondes Hadj Fredj, Sophie Bachellier-Bassi, Imène Najjar, Taieb Messaoud, Khadija Boussetta, Kalthoum Kallel, Helmi Mardassi, Christophe d'Enfert, Marie-Elisabeth Bougnoux, Sadri Znaidi
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012154 (2024)
Candida albicans chronically colonizes the respiratory tract of patients with Cystic Fibrosis (CF). It competes with CF-associated pathogens (e.g. Pseudomonas aeruginosa) and contributes to disease severity. We hypothesize that C. albicans undergoes
Externí odkaz:
https://doaj.org/article/3f782e6103b6485eb5a0f45c57ed332f
Publikováno v:
Bio-Protocol, Vol 14, Iss 3 (2024)
The human pathogenic yeast Candida albicans can attach to epithelial cells or indwelling medical devices to form biofilms. These microbial communities are highly problematic in the clinic as they reduce both sensitivity to antifungal drugs and detect
Externí odkaz:
https://doaj.org/article/b7d2d29d153b40b8a0d0ec0b216ffdff
Autor:
Thierry Mourer, Mennat El Ghalid, Gérard Pehau-Arnaudet, Brice Kauffmann, Antoine Loquet, Sébastien Brûlé, Vitor Cabral, Christophe d’Enfert, Sophie Bachellier-Bassi
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract The human commensal fungus Candida albicans can attach to epithelia or indwelling medical devices and form biofilms, that are highly tolerant to antifungal drugs and can evade the immune response. The cell surface protein Pga59 has been show
Externí odkaz:
https://doaj.org/article/8cd84241961946acb2fee85a8d833f53
Autor:
Thierry Mourer, Martin Sachse, Anastasia D. Gazi, Christophe d’Enfert, Sophie Bachellier-Bassi
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101514- (2022)
Summary: This protocol describes how to analyze C. albicans biofilm using transmission electron microscopy. We present two approaches to observe the ultrastructure of fungal cells within unperturbed biofilms, as well as an immunogold labeling procedu
Externí odkaz:
https://doaj.org/article/78f97c9a1ef142adbcd74de924aa836d
Autor:
Lasse van Wijlick, Sadri Znaidi, Arturo Hernández-Cervantes, Virginia Basso, Sophie Bachellier-Bassi, Christophe d’Enfert
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The alternate growth of Candida albicans between a unicellular yeast form and a multicellular hyphal form is crucial for its ability to cause disease. Interestingly, both morphological forms support distinct functions during proliferation in the huma
Externí odkaz:
https://doaj.org/article/ddc1c9b9ad654b83beeb1d72e288e9e9
Autor:
Arturo Hernández-Cervantes, Sadri Znaidi, Lasse van Wijlick, Iryna Denega, Virginia Basso, Jeanne Ropars, Natacha Sertour, Derek Sullivan, Gary Moran, Louise Basmaciyan, Fabienne Bon, Frédéric Dalle, Marie-Elisabeth Bougnoux, Teun Boekhout, Ying Yang, Zongwei Li, Sophie Bachellier-Bassi, Christophe d’Enfert
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Transcription factor Rme1 regulates meiosis and pseudohyphal growth in baker’s yeast, but its role in the meiosis-defective pathogen Candida albicans is unclear. Here, Hernández-Cervantes et al. show that Rme1 activates the expression of genes req
Externí odkaz:
https://doaj.org/article/3548548e39414be58497c9944b7e0844
Autor:
Laxmi Shanker Rai, Rima Singha, Hiram Sanchez, Tanmoy Chakraborty, Bipin Chand, Sophie Bachellier-Bassi, Shantanu Chowdhury, Christophe d'Enfert, David R Andes, Kaustuv Sanyal
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000422 (2019)
Histone H3 and its variants regulate gene expression but the latter are absent in most ascomycetous fungi. Here, we report the identification of a variant histone H3, which we have designated H3VCTG because of its exclusive presence in the CTG clade
Externí odkaz:
https://doaj.org/article/b094d36a5615467cbb30c39ff1121e87
Autor:
Vitor Cabral, Sadri Znaidi, Louise A Walker, Hélène Martin-Yken, Etienne Dague, Mélanie Legrand, Keunsook Lee, Murielle Chauvel, Arnaud Firon, Tristan Rossignol, Mathias L Richard, Carol A Munro, Sophie Bachellier-Bassi, Christophe d'Enfert
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004542 (2014)
Biofilm formation is an important virulence trait of the pathogenic yeast Candida albicans. We have combined gene overexpression, strain barcoding and microarray profiling to screen a library of 531 C. albicans conditional overexpression strains (∼
Externí odkaz:
https://doaj.org/article/2c7c3edc64634e77bd34d7ded8abae4b