Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sophie Altamirano"'
Autor:
Sophie Altamirano, Zhongming Li, Man Shun Fu, Minna Ding, Sophie R. Fulton, J. Marina Yoder, Vy Tran, Kirsten Nielsen
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Dysregulation of the cell cycle underlies many human genetic diseases and cancers, yet numerous organisms, including microbes, also manipulate the cell cycle to generate both morphologic and genetic diversity as a natural mechanism to enhance their c
Externí odkaz:
https://doaj.org/article/39d8b48d287541f58233cac724284fee
Autor:
Elliot S. Gerlach, Sophie Altamirano, J. Marina Yoder, Tony S. Luggya, Andrew Akampurira, David B. Meya, David R. Boulware, Joshua Rhein, Kirsten Nielsen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Half maximal inhibitory concentrations (IC50) to the experimental drug ATI-2307 and complete inhibition (IC90) of the common clinically used antifungal drug amphotericin B were determined by microbroth dilution assay for a collection of 69 clinical i
Externí odkaz:
https://doaj.org/article/b71de777415444a4b5da0a42162e0403
Autor:
Alex Hopke, Alex Mela, Felix Ellett, Derreck Carter-House, Jesús F Peña, Jason E Stajich, Sophie Altamirano, Brian Lovett, Martin Egan, Shiv Kale, Ilkka Kronholm, Paul Guerette, Edyta Szewczyk, Kevin McCluskey, David Breslauer, Hiral Shah, Bryan R Coad, Michelle Momany, Daniel Irimia
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257823 (2021)
Fungal hyphal growth and branching are essential traits that allow fungi to spread and proliferate in many environments. This sustained growth is essential for a myriad of applications in health, agriculture, and industry. However, comparisons betwee
Externí odkaz:
https://doaj.org/article/50a52dd44e9b41b2b2cff5b4117efc3d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Cryptococcus neoformans is a human fungal pathogen that can cause fatal meningitis in immunocompromised individuals. Fluconazole (FLC) is a fungistatic drug administered to treat cryptococcosis. When exposed to the inhibitory concentration of FLC, C.
Externí odkaz:
https://doaj.org/article/856e777f31b649bf883810f1c1a266af
Autor:
Sophie Altamirano, Diana Fang, Charles Simmons, Shreyas Sridhar, Peipei Wu, Kaustuv Sanyal, Lukasz Kozubowski
Publikováno v:
mSphere, Vol 2, Iss 3 (2017)
ABSTRACT Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies
Externí odkaz:
https://doaj.org/article/dc667f1f4bd3429fa3da9ec4cb974f89
Autor:
Congyue A. Peng, Sophie Altamirano, Namrata Paladugu, Logan P. Crowe, Inas F. Aboobakar, Srikripa Chandrasekaran, Lukasz Kozubowski
Publikováno v:
Fungal genetics and biology : FGB. 160
Cryptococcus neoformans, a basidiomycete yeast, causes lethal meningitis in immunocompromised individuals. The ability of C. neoformans to proliferate at 37°C is essential for virulence. We identified anillin-like protein, CnBud4, as essential for p
Autor:
Man Shun Fu, Kirsten Nielsen, Minna Ding, Vy Tran, Zhongming Li, J. Marina Yoder, Sophie Altamirano, Sophie R. Fulton
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response to the host lung environment that are critical for host adaptation and subsequent disease. We analyzed the in vivo and in vitro cell cycles to identify key aspect
Autor:
Yogesh, Sutar, Sophie R, Fulton, Sagarkumar, Paul, Sophie, Altamirano, Susmit, Mhatre, Hiwa, Saeed, Pratikkumar, Patel, Sudipta, Mallick, Roopal, Bhat, Vandana B, Patravale, Harsh, Chauhan, Kirsten, Nielsen, Abhijit A, Date
Publikováno v:
ACS Infect Dis
As the existing therapeutic modalities for the treatment of cryptococcal meningitis (CM) have suboptimal efficacy, repurposing existing drugs for the treatment of CM is of great interest. The FDA-approved anthelmintic benzimidazoles, albendazole, meb
Autor:
Man Shun Fu, Sophie R. Fulton, Sophie Altamirano, V. Tran, M. Ding, Zhongming Li, Kirsten Nielsen, J. M. Yoder
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response to the host lung environment that are critical for host adaptation and subsequent disease. We analyzed the in vivo and in vitro cell cycles to identify key aspect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a549d3104da70a91602dd0e225b57b14
https://doi.org/10.1101/2021.08.24.457603
https://doi.org/10.1101/2021.08.24.457603
Autor:
Kirsten Nielsen, Tony S. Luggya, Sophie Altamirano, J. Marina Yoder, Andrew Akampurira, Elliot S. Gerlach, David B. Meya, David R. Boulware, Joshua Rhein
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Half maximal inhibitory concentrations (IC50) to the experimental drug ATI-2307 and complete inhibition (IC90) of the common clinically used antifungal drug amphotericin B were determined by microbroth dilution assay for a collection of 69 clinical i