Výsledky vyhledávání - "Sophie A Matthews"

Akademický článek

Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death

Autor: Teresa L. M. Thurston, Sophie A. Matthews, Elliott Jennings, Eric Alix, Feng Shao, Avinash R. Shenoy, Mark A. Birrell, David W. Holden

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)

Inflammatory caspases restrict microbial growth by inducing cytokine production and pyroptosis, but other caspase-induced mechanisms are thought to contribute. Here the authors use time-lapse microscopy of single cells to show that caspase1/11 has an

Externí odkaz: https://doaj.org/article/3dcaf1a910524de0b958aea81b142880

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Akademický článek

Inhibition of Nuclear Transport of NF-ĸB p65 by the Salmonella Type III Secretion System Effector SpvD.

Autor: Nathalie Rolhion, R Christopher D Furniss, Grzegorz Grabe, Aindrias Ryan, Mei Liu, Sophie A Matthews, David W Holden

Publikováno v: PLoS Pathogens, Vol 12, Iss 5, p e1005653 (2016)

Salmonella enterica replicates in macrophages through the action of effector proteins translocated across the vacuolar membrane by a type III secretion system (T3SS). Here we show that the SPI-2 T3SS effector SpvD suppresses proinflammatory immune re

Externí odkaz: https://doaj.org/article/b56fb80b5a1e43b8957b80d1b2aede65

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Akademický článek

Mutational and topological analysis of the Escherichia coli BamA protein.

Autor: Douglas F Browning, Sophie A Matthews, Amanda E Rossiter, Yanina R Sevastsyanovich, Mark Jeeves, Jessica L Mason, Timothy J Wells, Catherine A Wardius, Timothy J Knowles, Adam F Cunningham, Vassiliy N Bavro, Michael Overduin, Ian R Henderson

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84512 (2013)

The multi-protein β-barrel assembly machine (BAM) of Escherichia coli is responsible for the folding and insertion of β-barrel containing integral outer membrane proteins (OMPs) into the bacterial outer membrane. An essential component of this comp

Externí odkaz: https://doaj.org/article/fbb122cf1a7847f49a1ee1f57376a9d6

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The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules

Autor: Samkeliso V Blundell, Mei Liu, Tabitha Sleap, Kirby N. Swatek, Camilla Godlee, Jonathan N. Pruneda, David W. Holden, Eric Alix, Romina Tocci, David Komander, Sophie A. Matthews, Ondrej Cerny

Publikováno v: Cell Host & Microbe
CELL HOST & MICROBE
68.e7

Summary The Salmonella enterica effector SteD depletes mature MHC class II (mMHCII) molecules from the surface of infected antigen-presenting cells through ubiquitination of the cytoplasmic tail of the mMHCII β chain. Here, through a genome-wide mut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699f3ec7e2d81422dd9450f82b8e9835
https://pubmed.ncbi.nlm.nih.gov/32526160

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Recruitment of TBK 1 to cytosol‐invading Salmonella induces WIPI 2‐dependent antibacterial autophagy

Autor: Teresa L. M. Thurston, Keith B. Boyle, Stuart Bloor, Maryia Karpiyevich, Ágnes Foeglein, Felix Randow, Benjamin J. Ravenhill, Annie Kaul, David Komander, Mark Bycroft, Jessica Noad, Mark D. Allen, Sophie A. Matthews

Publikováno v: The EMBO Journal

Mammalian cells deploy autophagy to defend their cytosol against bacterial invaders. Anti‐bacterial autophagy relies on the core autophagy machinery, cargo receptors, and “eat‐me” signals such as galectin‐8 and ubiquitin that label bacteria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ea056437c719e68b712943d7d5eb8f
https://doi.org/10.15252/embj.201694491

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Correction for Günster et al., 'SseK1 and SseK3 Type III Secretion System Effectors Inhibit NF-κB Signaling and Necroptotic Cell Death in Salmonella-Infected Macrophages'

Autor: Regina A. Günster, Teresa L. M. Thurston, David W. Holden, Sophie A. Matthews

Publikováno v: Infection and Immunity. 85

Volume 85, no. 3, e00010-17, 2017, [https://doi.org/10.1128/IAI.00010-17][1]. Page 3: [Figure 1][2] should appear as shown below. The original figure contained a partial duplication in panel A, rows 5 and 7, as the result of an error in figure prepar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c06e02fc5861991c4bf8ea4c43df410d
https://doi.org/10.1128/iai.00242-17

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Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

Autor: David W. Holden, Laura M. Faure, Sophie Helaine, Angela M. Cheverton, Kathryn G. Watson, Sophie A. Matthews

Publikováno v: Science. 343:204-208

Persistent Survival The role of persister cells—dormant cells that survive multidrug treatment—in the context of bacterial pathogenesis has not been explored in depth. Using a single-cell fluorescent dilution technique, Helaine et al. (p. 204 ) e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546d52c2ca071f26983ebb95f80e703f
https://doi.org/10.1126/science.1244705

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Inhibition of Nuclear Transport of NF-kappa B p65 by the Salmonella Type III Secretion System Effector SpvD

Autor: R. Christopher D. Furniss, Mei Liu, Grzegorz J. Grabe, Nathalie Rolhion, David W. Holden, Sophie A. Matthews, Aindrias S. Ryan

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2016, 12 (5), ⟨10.1371/journal.ppat.1005653⟩
Plos Pathogens 5 (12), . (2016)
PLoS Pathogens, Vol 12, Iss 5, p e1005653 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dbd901a559b342ca309c30048c11dc
https://hal.inrae.fr/hal-02631253/document

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