Výsledky vyhledávání - "Sophie A, van Diest"

Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms

Autor: Rafael Simone Saia, Anne S. Strik, Daniel Keszthelyi, Frank H. J. Schuren, Rene M. van den Wijngaard, Zhumei Yu, Daniele Maria-Ferreira, Wouter J. de Jonge, Ronald P.J. Oude Elferink, Gary Jennings, Sophie A. van Diest, Sigrid E.M. Heinsbroek, Olaf Welting, Isabelle A. M. van Thiel, Sara Botschuijver

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports
Scientific Reports, 9:12530. Nature Publishing Group
Scientific reports, 9(1):12530. Nature Publishing Group

Irritable bowel syndrome (IBS) is a heterogenic, functional gastrointestinal disorder of the gut-brain axis characterized by altered bowel habit and abdominal pain. Preclinical and clinical results suggested that, in part of these patients, pain may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6b9a67c1d14308de0e62456f1586f9
http://link.springer.com/article/10.1038/s41598-019-49096-y

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Akademický článek

Stress-induced visceral hypersensitivity in maternally separated rats can be reversed by peripherally restricted histamine-1-receptor antagonists.

Autor: Oana I Stanisor, Sophie A van Diest, Zhumei Yu, Olaf Welting, Noor Bekkali, Jing Shi, Wouter J de Jonge, Guy E Boeckxstaens, Rene M van den Wijngaard

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e66884 (2013)

BACKGROUND: The histamine-1 receptor (H1R) antagonist ketotifen increased the threshold of discomfort in hypersensitive IBS patients. The use of peripherally restricted and more selective H1R antagonists may further improve treatment possibilities. W

Externí odkaz: https://doaj.org/article/c1c3fa46129e44e1870bde7e0a338ea6

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Dietary Marine n–3 PUFAs Do Not Affect Stress-Induced Visceral Hypersensitivity in a Rat Maternal Separation Model1–3

Autor: Guy E. Boeckxstaens, Ingrid C. Gaemers, Wouter J. de Jonge, Lieke W J van den Elsen, Sophie A. van Diest, Bert J. M. van de Heijning, Maria Fernanda de Paula Werner, Francisca W. Hilbers, Linette E M Willemsen, Allison J Klok, Rene M. van den Wijngaard, Olaf Welting

Publikováno v: The Journal of Nutrition. 145:915-922

Background: Although never evaluated for efficacy, n-3 (ω-3) long-chain polyunsaturated fatty acids (LCPUFAs) are commercially offered as treatment for irritable bowel syndrome (IBS). Objective: This study was designed to investigate, in a mast cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32e6260cc0c4bd0a571a44ccb1ac2474
https://doi.org/10.3945/jn.114.201731

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Relevance of mast cell-nerve interactions in intestinal nociception

Autor: Oana I. Stanisor, Wouter J. de Jonge, Sophie A. van Diest, G. E. E. Boeckxstaens, Rene M. van den Wijngaard

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1822(1):74-84

Cross-talk between the immune- and nervous-system is considered an important biological process in health and disease. Because mast cells are often strategically placed between nerves and surrounding (immune)cells they may function as important inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5c6591395464f475466824000d5bb1
https://doi.org/10.1016/j.bbadis.2011.03.019

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Dietary Marine n-3 PUFAs Do Not Affect Stress-Induced Visceral Hypersensitivity in a Rat Maternal Separation Model

Autor: Sophie A, van Diest, Lieke W J, van den Elsen, Allison J, Klok, Olaf, Welting, Francisca W, Hilbers, Bert J, van de Heijning, Ingrid C, Gaemers, Guy E, Boeckxstaens, Maria F, Werner, Linette E M, Willemsen, Wouter J, de Jonge, René M, van den Wijngaard

Publikováno v: The Journal of nutrition. 145(5)

Although never evaluated for efficacy, n-3 (ω-3) long-chain polyunsaturated fatty acids (LCPUFAs) are commercially offered as treatment for irritable bowel syndrome (IBS).This study was designed to investigate, in a mast cell-dependent model for vis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48508b9c81e7a1c824b9ecfd95a59850
https://pubmed.ncbi.nlm.nih.gov/25716554

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Stress-induced visceral hypersensitivity in maternally separated rats can be reversed by peripherally restricted histamine-1-receptor antagonists

Autor: Noor L. Bekkali, Wouter J. de Jonge, Sophie A. van Diest, Jing Shi, Guy E. Boeckxstaens, Rene M. van den Wijngaard, Zhumei Yu, Oana I. Stanisor, Olaf Welting

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e66884 (2013)
PLoS ONE, 8(6). Public Library of Science
PLoS ONE; Vol 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bd7bc0f8458a36a0bba606cbfd37b5
https://pubmed.ncbi.nlm.nih.gov/23776699

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