Les élevages pour questionner la relation à l’animal avec des élèves de maternelle

Autor: Raphaël Chalmeau, Monique Lafitole, Sophie Mourgues, Maéva Ramos Béato, Gabrielle Bergamaschi, Lucile Mortelecque, Dorothée Sales-Hitier

Publikováno v: Recherches en Éducation, Vol 56 (2024)

From kindergarten onwards, raising animals in the classroom is particularly appropriate for building an observational approach and for developing a sense of responsibility towards animals. The relationship between humans and non-humans is a renewed r

Externí odkaz: https://doaj.org/article/2c68b03a853241dd82b084443c91d3bd

A Single Nuclease-Resistant Linkage in DNA as a Versatile Tool for the Characterization of DNA Lesions: Application to the Guanine Oxidative Lesion 'G+34' Generated by Metalloporphyrin/KHSO5 Reagent

Autor: Agnieszka Tomaszewska, Sophie Mourgues, Piotr Guga, Geneviève Pratviel, Barbara Nawrot

Publikováno v: Chemical Research in Toxicology. 25:2505-2512

The oxidation of an oligonucleotide containing a single nuclease-resistant phosphodiester link, a stereoisomerically pure methylphosphonate, by manganese (Mn-TMPyP) or iron (Fe-TMPyP) porphyrin associated to KHSO(5) allowed the isolation and characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af254ecb33c28cc3aee3909f5e599d22
https://doi.org/10.1021/tx300319y

The P-Stereocontrolled Synthesis of PO/PS-Chimeric Oligonucleotides by Incorporation of Dinucleoside Phosphorothioates Bearing anO-4-Nitrophenyl Phosphorothioate Protecting Group

Autor: Geneviève Pratviel, Bernard Meunier, Lucyna A. Wozniak, Wojciech J. Stec, Malgorzata Bukowiecka-Matusiak, Marcin Góra, Sophie Mourgues

Publikováno v: European Journal of Organic Chemistry. 2005:2924-2930

The synthesis of protected model dinucleoside (3',5')-O-aryl phosphorothioates, their separation into pure diastereomers, and their successful incorporation into oligonucleotides followed by stereospecific deprotection of the O-aryl phosphorothioate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb060e39676a37685a012da2cb76c81e
https://doi.org/10.1002/ejoc.200400910

ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair

Autor: Pierre-Olivier Mari, Christine Bordier, Anne Gonzales de Peredo, Anna Lagarou, Wim Vermeulen, Bernard Monsarrat, Lara Kaddoum, Joris Slingerland, Giuseppina Giglia-Mari, Violette Gautier, Sophie Mourgues, Amandine Mourcet, Frédéric Coin

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (44), pp.17927-17932. ⟨10.1073/pnas.1305009110⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (44), pp.17927-17932. ⟨10.1073/pnas.1305009110⟩
Proceedings of the National Academy of Sciences of the U.S.A., 110(44), 17927-17932. National Academy of Sciences

International audience; DNA lesions that block transcription may cause cell death even when repaired, if transcription does not restart to reestablish cellular metabolism. However, transcription resumption after individual DNA-lesion repair remains p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3332dbecd82185912f8473a6de78c2ff
https://hal.science/hal-03542278

Differentiation Driven Changes in the Dynamic Organization of Basal Transcription Initiation

Autor: Alex Maas, Catherine Miquel, Jan H.J. Hoeijmakers, Wim Vermeulen, Jan de Wit, Lise O. Andrieux, Nils Wijgers, Maria Fousteri, Pierre-Olivier Mari, Julie Nonnekens, Sophie Mourgues, Arjan F. Theil, Giuseppina Giglia-Mari

Publikováno v: PLoS Biology
PLoS Biology, Public Library of Science, 2009, 7 (10), pp.e1000220. ⟨10.1371/journal.pbio.1000220⟩
PLoS Biology, Vol 7, Iss 10, p e1000220 (2009)
PLoS Biology (print), 7(10). Public Library of Science

A novel mouse model reveals that the dynamic behavior of transcription factors can vary considerably between different cells of an organism.
Studies based on cell-free systems and on in vitro–cultured living cells support the concept that many

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896e3b957ec0d252ee01e5c1db1f3334
https://doi.org/10.1371/journal.pbio.1000220