Sex hormone regulation of innate lymphoid cells

Autor: Eve Blanquart, Sophie Laffont, Jean-Charles Guéry

Publikováno v: Biomedical Journal, Vol 44, Iss 2, Pp 144-156 (2021)

Innate lymphoid cell (ILC) subsets at barrier surfaces contribute to maintain tissue homeostasis and appropriate responses to infection. ILCs respond to environmental factors produced by non-hematopoietic cells within tissues, but also circulating cy

Externí odkaz: https://doaj.org/article/8bb07542b5a341c8b64d17469bd0a0f1

188Re-SSS Lipiodol Radioembolization in HCC Patients: Results of a Phase 1 Trial (Lip-Re-01 Study)

Autor: Etienne Garin, Xavier Palard, Yan Rolland, Samuel Le Sourd, Nicolas Lepareur, Valérie Ardisson, Christelle Bouvry, Sophie Laffont, Boris Campillo-Gimenez, Eric Bellissant, Julien Edeline

Publikováno v: Cancers; Volume 15; Issue 8; Pages: 2245
Cancers
Cancers, 2023, 15 (8), pp.2245. ⟨10.3390/cancers15082245⟩

International audience; Simple Summary Radioembolization is a kind of internal radiation therapy which is currently used in non-operable HCC. Several radiolabeled product can be used as Y-90-loaded microspheres or less frequently radiolabeled lipiodo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c18bf81430382bbdaefda03b52113b

Health-related quality of life in locally advanced hepatocellular carcinoma treated by either radioembolisation or sorafenib (SARAH trial)

Autor: Helena Pereira, Mohamed Bouattour, Marco D. Burgio, Eric Assenat, Jules Grégory, Jean-Pierre Bronowicki, Gilles Chatellier, Valérie Vilgrain, Elisabeth Delhom-Christol, Marjolène Fourcade, Boris Guiu, Alina Diana Ilonca, Julie Lonjon, Georges-Philippe Pageaux, Mohamed Abdel-Rehim, Wassim Allaham, Laurent Castera, Arnaud Dieudonné, Rachida Lebtahi, Maxime Ronot, Annie Sibert, Hélène Chor, Julie Devictor, Hélène Barraud, Christophe Bazin, Laetitia Imbert, Valérie Laurent, Elodie Mathias, Carine Chagneau-Derrode, Christelle Gallais, Rémy Perdrisot, Christine Silvain, Jean Pierre Tasu, Patrick Borentain, Bardia Farman, René Gerolami, Olivier Mundler, Jean-Francois Seitz, Vincent Vidal, Christophe Aubé, Francis Bouchet, Antoine Bouvier, Olivier Couturier, Frédéric Oberti, Laurent Vervueren, Isabelle Brenot-Rossi, Julien Darreon, Jean Luc Raoul, Anthony Sarran, Julia Chalaye, Charlotte Costentin, Emmanuel Itti, Hicham Kobeiter, Alain Luciani, Hélène Masset, René Adam, Maïté Lewin, Didier Samuel, Julien Edeline, Etienne Garin, Sophie Laffont, Yan Rolland, Isabelle Archambeaud, Thomas Carlier, Thomas Eugene, Eric Frampas, Christophe Cassinotto, Martine Guyot, Jean-Baptiste Hiriart, Bruno Lapuyade, Karine Tendero, Julien Vergniol, Philippe Bachellier, Julien Détour, Bernard Duclos, Michel Greget, Francois Habersetzer, Alessio Imperiale, Elise Enderlin, Philippe Merle, Agnès Rode, Julie Morvan, Eric Nguyen-Khac, Antoine Talbot, Thierry Yzet, Guillaume Baudin, Patrick Chevallier, Abakar Mahamat, Fabien Maurel, Thierry Piche, Micheline Razzouk, Patrick Hillon, Romaric Loffroy, Michel Toubeau, Julie Vincent, Jean-Marc Vrigneaud, Gabriele Barabino, Nadia Bouarioua, Muriel Cuilleron, Marie Ecochard, Nathalie Prevot-Bitot, Evelyne Rousset, Vincent Leroy, Ghislaine Reboulet, Julie Roux, Christian Sengel, Valérie Bourcier, Nathalie Ganne-Carrie, Olivier Seror, Sylvie Costo, Thông Dao, Cédric Desmonts, Jean-Pierre Pelage, Didier Defez, Jérôme Dumortier, Francesco Giammarile, Pierre-Jean Valette, Michela Bernardini, Nadia Ghazar, Olivier Pellerin, Julien Taieb, Pierre Weinmann, Alexandra Heurgue-Berlot, Claude Marcus, Daniele Sommacale, Maria-Angéla Castilla-Lièvre, Aurélie Forbes, Sophie Maitre, Lysiane Marthey

Publikováno v: European Journal of Cancer
European Journal of Cancer, Elsevier, 2021, 154, pp.46-56. ⟨10.1016/j.ejca.2021.05.032⟩

Background The aim of this ancillary study of the SARAH trial is to compare health-related quality of life (HRQoL) in patients with locally advanced or inoperable hepatocellular carcinoma (HCC) treated with transarterial radioembolisation (TARE) or s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813a4496fe7c63c5833e2c6c0dfdee24
https://doi.org/10.1016/j.ejca.2021.05.032

Personalised versus standard dosimetry approach of selective internal radiation therapy in patients with locally advanced hepatocellular carcinoma (DOSISPHERE-01): a randomised, multicentre, open-label phase 2 trial

Autor: Etienne Garin, Lambros Tselikas, Boris Guiu, Julia Chalaye, Julien Edeline, Thierry de Baere, Eric Assenat, Vania Tacher, Corentin Robert, Marie Terroir-Cassou-Mounat, Denis Mariano-Goulart, Giuliana Amaddeo, Xavier Palard, Antoine Hollebecque, Marilyne Kafrouni, Hélène Regnault, Karim Boudjema, Serena Grimaldi, Marjolaine Fourcade, Hicham Kobeiter, Eric Vibert, Samuel Le Sourd, Lauranne Piron, Danièle Sommacale, Sophie Laffont, Boris Campillo-Gimenez, Yan Rolland, Corentin Robert Robert, Marc Pracht, Valérie Ardisson, Laurence Lenoir, Thierry De Baere, Frederic Deschamps, Michel Ducreux, Maximiliano Gelli, Christophe Cassinotto, Carole Allimant, Sophie Bonnot-Lours, Margarita Marie, Emmanuel Itti, Lionel Lerman, Mukedaisi Abulizi, Alain Luciani, Charlotte E. Costentin, Milan Milliner

Publikováno v: The Lancet Gastroenterology and Hepatology
The Lancet Gastroenterology and Hepatology, Elsevier, 2021, 6 (1), pp.17-29. ⟨10.1016/S2468-1253(20)30290-9⟩
The Lancet Gastroenterology & Hepatology
The Lancet Gastroenterology & Hepatology, 2021, 6 (1), pp.17-29. ⟨10.1016/S2468-1253(20)30290-9⟩

International audience; BACKGROUND: All randomised phase 3 studies of selective internal radiation therapy for advanced hepatocellular carcinoma published to date have reported negative results. However, these studies did not use personalised dosimet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffe9509de2017fb502074bc3c3a223a
https://doi.org/10.1016/s2468-1253(20)30290-9

TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women

Autor: Jean-Charles Guéry, Jacques Izopet, Asma Essat, Arnoo Shaiykova, Caroline Passaes, Sophie Laffont, Ali Youness, Pascal Azar, Michaela Müller-Trutwin, José E. Mejía, Pierre Delobel, Laurence Meyer, Claire Cenac

Publikováno v: JCI Insight
JCI Insight, American Society for Clinical Investigation, 2020, 5 (12), ⟨10.1172/jci.insight.136047⟩
JCI Insight, American Society for Clinical Investigation, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩
JCI Insight, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩

International audience; Type I IFN (IFN-I) production by plasmacytoid DCs (pDCs) occurs during acute HIV-1 infection in response to TLR7 stimulation, but the role of pDC-derived IFN-I in controlling or promoting HIV-1 infection is ambiguous. We repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8932b542dcf842ba7049a0070c46a9
https://hal.archives-ouvertes.fr/hal-03012855