Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Sophie, Hernot"'
Autor:
Laura Teodori, Sarah K. Ochoa, Marjan Omer, Veronica L. Andersen, Pernille Bech, Junyi Su, Jessica Bridoux, Jesper S. Nielsen, Mathias B. Bertelsen, Sophie Hernot, Kurt V. Gothelf, Jørgen Kjems
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 3, Pp 102305- (2024)
In cancer molecular imaging, selecting binders with high specificity and affinity for biomarkers is paramount for achieving high-contrast imaging within clinical time frames. Nanobodies have emerged as potent candidates, surpassing antibodies in pre-
Externí odkaz:
https://doaj.org/article/433c78f861d246df826c2c03401e36f5
Autor:
Łukasz Mateusiak, Sam Floru, Timo W. M. De Groof, Janne Wouters, Noemi B. Declerck, Pieterjan Debie, Simone Janssen, Katty Zeven, Janik Puttemans, Cécile Vincke, Karine Breckpot, Nick Devoogdt, Sophie Hernot
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Fluorescence molecular imaging plays a vital role in image‐guided surgery. In this context, the urokinase plasminogen activator receptor (uPAR) is an interesting biomarker enabling the detection and delineation of various tumor types due t
Externí odkaz:
https://doaj.org/article/a377899d68f44206a97cf26504119978
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intra-operative fluorescence imaging has demonstrated its ability to improve tumor lesion identification. However, the limited tissue penetration of the fluorescent signals hinders the detection of deep-lying or occult lesions. Integrating fluorescen
Externí odkaz:
https://doaj.org/article/4ed358f73c514470a0f61f1dc7f1a5f1
Autor:
Nayra Cristina Herreira do Valle, Simone Janssen, Marcus C. M. Stroet, Sofie Pollenus, Sonja Van den Block, Nick Devoogdt, Jens M. Debacker, Sophie Hernot, Hilde De Rooster
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Surgical resection is one of the main treatment options for several types of cancer, the desired outcome being complete removal of the primary tumor and its local metastases. Any malignant tissue that remains after surgery may lead to r
Externí odkaz:
https://doaj.org/article/b01ed89338af43ffbfb2caa65f7817f3
Publikováno v:
Animals, Vol 13, Iss 16, p 2581 (2023)
According to the EU Directive 2010/63, all animal procedures must be classified as non-recovery, mild, moderate or severe. Several examples are included in the Directive to help in severity classification. Since the implementation of the Directive, d
Externí odkaz:
https://doaj.org/article/ff71ec8e4e8d4d47baed2598d426c433
Autor:
Zohreh Varasteh, Miriam Braeuer, Sarajo Mohanta, Anna-Lena Steinsiek, Andreas Habenicht, Negar Omidvari, Geoffrey J. Topping, Christoph Rischpler, Wolfgang A. Weber, Hendrik B. Sager, Geert Raes, Sophie Hernot, Markus Schwaiger
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Introduction and ObjectivesWound healing after myocardial infarction (MI) is a dynamic and complex multiple phase process, and a coordinated cellular response is required for proper scar formation. The current paradigm suggests that pro-inflammatory
Externí odkaz:
https://doaj.org/article/d98225bbd7ee46938dfd124252dd82bd
Autor:
Labrinus van Manen, Lizzie D. A. N. de Muynck, Victor M. Baart, Shadhvi Bhairosingh, Pieterjan Debie, Alexander L. Vahrmeijer, Sophie Hernot, J. Sven D. Mieog
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 618 (2023)
Molecular fluorescence-guided surgery using near-infrared light has the potential to improve the rate of complete resection of cancer. Typically, monoclonal antibodies are being used as targeting moieties, however smaller fragments, such as single-do
Externí odkaz:
https://doaj.org/article/23f7d3ac1450443282f7ee0bc2b99bcf
Autor:
Zohreh Varasteh, Sarajo Mohanta, Yuanfang Li, Nicolás López Armbruster, Miriam Braeuer, Stephan G. Nekolla, Andreas Habenicht, Hendrik B. Sager, Geert Raes, Wolfgang Weber, Sophie Hernot, Markus Schwaiger
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background Rupture-prone atherosclerotic plaques are characterized by heavy macrophage infiltration, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR, CD206) is over-expressed
Externí odkaz:
https://doaj.org/article/a6e02592a36643b49568dc4b627a95cd
Autor:
Evangelia Bolli, Maximilian Scherger, Sana M. Arnouk, Ana Rita Pombo Antunes, David Straßburger, Moritz Urschbach, Judith Stickdorn, Karen De Vlaminck, Kiavash Movahedi, Hans Joachim Räder, Sophie Hernot, Pol Besenius, Jo A. Van Ginderachter, Lutz Nuhn
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies. To repolarize their phenotype into a
Externí odkaz:
https://doaj.org/article/cac8fa4c5d6f47508fc134a4bcd703ea
Autor:
Thinzar M. Lwin, Michael A. Turner, Hiroto Nishino, Siamak Amirfakhri, Sophie Hernot, Robert M. Hoffman, Michael Bouvet
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 711 (2022)
Tumor-specific targeting with fluorescent probes can enhance contrast for identification of cancer during surgical resection and visualize otherwise invisible tumor margins. Nanobodies are the smallest naturally-occurring antigen-binding molecules wi
Externí odkaz:
https://doaj.org/article/ce3c37d8bca743d29619797debdbe660