Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sophie, George"'
Autor:
Samuel Lipworth, William Matlock, Liam Shaw, Karina-Doris Vihta, Gillian Rodger, Kevin Chau, Leanne Barker, Sophie George, James Kavanagh, Timothy Davies, Alison Vaughan, Monique Andersson, Katie Jeffery, Sarah Oakley, Marcus Morgan, Susan Hopkins, Timothy Peto, Derrick Crook, A. Sarah Walker, Nicole Stoesser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Plasmids carry genes conferring antimicrobial resistance and other clinically important traits, and contribute to the rapid dissemination of such genes. Previous studies using complete plasmid assemblies, which are essential for reliable inf
Externí odkaz:
https://doaj.org/article/c56d4a213dff4d18a116a92ca0f30949
Autor:
Samuel Lipworth, William Matlock, Liam Shaw, Karina-Doris Vihta, Gillian Rodger, Kevin Chau, Leanne Barker, Sophie George, James Kavanagh, Timothy Davies, Alison Vaughan, Monique Andersson, Katie Jeffery, Sarah Oakley, Marcus Morgan, Susan Hopkins, Timothy Peto, Derrick Crook, A. Sarah Walker, Nicole Stoesser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/209037be1bab444f9b92b7f0752b0ceb
Autor:
Sam Lipworth, Karina-Doris Vihta, Tim Davies, Sarah Wright, Merline Tabirao, Kevin Chau, Alison Vaughan, James Kavanagh, Leanne Barker, Sophie George, Shelley Segal, Stephane Paulus, Lucinda Barrett, Sarah Oakley, Katie Jeffery, Lisa Butcher, Tim Peto, Derrick Crook, Sarah Walker, Seilesh Kadambari, Nicole Stoesser
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-8 (2022)
Lipworth et al. conduct a molecular epidemiological analysis of Gram-negative bloodstream infections in children in Oxfordshire, England, over a 10-year period. The authors report E. coli as the main causative agent and observe a similar population s
Externí odkaz:
https://doaj.org/article/9aa0fffdd2154dd79c89967aa0f055dd
Autor:
Samuel Lipworth, Karina-Doris Vihta, Kevin Chau, Leanne Barker, Sophie George, James Kavanagh, Timothy Davies, Alison Vaughan, Monique Andersson, Katie Jeffery, Sarah Oakley, Marcus Morgan, Susan Hopkins, Timothy E. A. Peto, Derrick W. Crook, Ann Sarah Walker, Nicole Stoesser
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background The incidence of Gram-negative bloodstream infections (BSIs), predominantly caused by Escherichia coli and Klebsiella species, continues to increase; however, the causes of this are unclear and effective interventions are therefor
Externí odkaz:
https://doaj.org/article/274d0b043eb44122935b36015055c9b9
Autor:
Rachel M. Colquhoun, Michael B. Hall, Leandro Lima, Leah W. Roberts, Kerri M. Malone, Martin Hunt, Brice Letcher, Jane Hawkey, Sophie George, Louise Pankhurst, Zamin Iqbal
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-30 (2021)
Abstract We present pandora, a novel pan-genome graph structure and algorithms for identifying variants across the full bacterial pan-genome. As much bacterial adaptability hinges on the accessory genome, methods which analyze SNPs in just the core g
Externí odkaz:
https://doaj.org/article/3bf384fd17904ec49e3cda3805c804b4
Autor:
Michael B Hall, Marie Sylvianne Rabodoarivelo, Anastasia Koch, Anzaan Dippenaar, Sophie George, Melanie Grobbelaar, Robin Warren, Timothy M Walker, Helen Cox, Sebastien Gagneux, Derrick Crook, Tim Peto, Niaina Rakotosamimanana, Simon Grandjean Lapierre, Zamin Iqbal
BACKGROUND: Mycobacterium tuberculosis whole-genome sequencing (WGS) has been widely used for genotypic drug susceptibility testing (DST) and outbreak investigation. For both applications, Illumina technology is used by most public health laboratorie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2899f07670ab4efcb45f20c6bf972c7f
Autor:
Kayzad Nilgiriwala, Marie-Sylvianne Rabodoarivelo, Michael B. Hall, Grishma Patel, Ayan Mandal, Shefali Mishra, Fanantenana Randria Andrianomanana, Kate Dingle, Gillian Rodger, Sophie George, Derrick W. Crook, Sarah Hoosdally, Nerges Mistry, Niaina Rakotosamimanana, Zamin Iqbal, Simon Grandjean Lapierre, Timothy M. Walker
BackgroundUniversal access to drug susceptibility testing for newly diagnosed tuberculosis patients is recommended. Access to culture-based diagnostics remains limited and targeted molecular assays are vulnerable to emerging resistance conferring mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc911b7b2ef51f87ce6f9e0ce8b37be
https://doi.org/10.1101/2022.10.31.514503
https://doi.org/10.1101/2022.10.31.514503
Autor:
Samuel Lipworth, James Kavanagh, Katie Jeffery, Derrick W. Crook, Marcus Morgan, Nicole Stoesser, Karina-Doris Vihta, Ali Vaughan, Kevin K Chau, Leanne Barker, Sarah Oakley, Timothy J. Davies, Tim E. A. Peto, Monique Andersson, A. Sarah Walker, Sophie George
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background The incidence of bloodstream infections (BSIs) caused by Escherichia coli and Klebsiella pneumoniae is increasing, with substantial associated morbidity, mortality, and antimicrobial resistance. Unbiased serotyping studies to guide vaccine
Autor:
Samuel Lipworth, Willam Matlock, Liam Shaw, Karina-Doris Vihta, Gillian Rodger, Kevin Chau, Leanne Barker, Sophie George, James Kavanagh, Timothy Davies, Alison Vaughan, Monique Andersson, Katie Jeffery, Sarah Oakley, Marcus Morgan, Susan Hopkins, Timothy Peto, Derrick Crook, A. Sarah Walker, Nicole Stoesser
Plasmids carry genes conferring antimicrobial resistance (AMR), and other clinically important traits; their ability to move within and between species may provide the machinery for rapid dissemination of such genes. Existing studies using complete p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f716ab90ed7291416a9fd0a2f3542f71
https://doi.org/10.1101/2022.04.03.22273290
https://doi.org/10.1101/2022.04.03.22273290
Autor:
Sam Lipworth, Karina-Doris Vihta, Tim Davies, Sarah Wright, Merline Tabirao, Kevin Chau, Alison Vaughan, James Kavanagh, Leanne Barker, Sophie George, Shelley Segal, Stephane Paulus, Lucinda Barrett, Sarah Oakley, Katie Jeffery, Lisa Butcher, Tim Peto, Derrick Crook, Sarah Walker, Seilesh Kadambari, Nicole Stoesser
Publikováno v:
Communications medicine. 2
Background Gram-negative organisms are common causes of bloodstream infection (BSI) during the neonatal period and early childhood. Whilst several large studies have characterised these isolates in adults, equivalent data (particularly incorporating