Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sophia Vincoff"'
Autor:
Garyk Brixi, Tianzheng Ye, Lauren Hong, Tian Wang, Connor Monticello, Natalia Lopez-Barbosa, Sophia Vincoff, Vivian Yudistyra, Lin Zhao, Elena Haarer, Tianlai Chen, Sarah Pertsemlidis, Kalyan Palepu, Suhaas Bhat, Jayani Christopher, Xinning Li, Tong Liu, Sue Zhang, Lillian Petersen, Matthew P. DeLisa, Pranam Chatterjee
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Protein-protein interactions (PPIs) are critical for biological processes and predicting the sites of these interactions is useful for both computational and experimental applications. We present a Structure-agnostic Language Transformer and
Externí odkaz:
https://doaj.org/article/c386e40794b146948717287a87e8d486
Autor:
Divya L. Dayanidhi, Jason A. Somarelli, John B. Mantyh, Gabrielle Rupprecht, Roham Salman Roghani, Sophia Vincoff, Iljin Shin, Yiquan Zhao, So Young Kim, Shannon McCall, Jiyong Hong, David S. Hsu
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/3ce819b3570744e6b93e60cc70e9e3ea
Autor:
Divya L. Dayanidhi, Jason A. Somarelli, John B. Mantyh, Gabrielle Rupprecht, Roham Salman Roghani, Sophia Vincoff, Iljin Shin, Yiquan Zhao, So Young Kim, Shannon McCall, Jiyong Hong, David S. Hsu
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Colorectal cancer (CRC) is the third most prevalent form of cancer in the United States and results in over 50,000 deaths per year. Treatments for metastatic CRC are limited, and therefore there is an unmet clinical need for more effective therapies.
Externí odkaz:
https://doaj.org/article/a7ae9050338a4bf4b109f13416c91426
Autor:
Garyk Brixi, Tianzheng Ye, Kalyan Palepu, Lauren Hong, Vivian Yudistyra, Sophia Vincoff, Jayani Christopher, Xinning Li, Suhaas Bhat, Connor Monticello, Natalia Lopez-Barbosa, Lillian Petersen, Tian-Lai Zang, Tong Liu, Lin Zhao, Sue Zhang, Manvitha Ponnapati, Emma Tysinger, Teodora Stan, Sabrina Koseki, Matthew DeLisa, Pranam Chatterjee
Here, we integrate fine-tuned protein language models and protein-protein interaction databases to develop a Structure-agnostic Language Transformer & Peptide Prioritization module that efficiently selects peptides from interaction interfaces, withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe54c68539f2d58a2da2d3a773bed263
https://doi.org/10.21203/rs.3.rs-1694183/v1
https://doi.org/10.21203/rs.3.rs-1694183/v1
Autor:
Christian Kramme, Merrick Smela, Bennett Wolf, Patrick Fortuna, Garyk Brixi, Tian-Lai Zang, Sophia Vincoff, Kalyan Palepu, Sabrina Koseki, Suhaas Bhat, Edward Dong, Jessica Adams, Richie Kohman, Songlei Liu, Mutsumi Kobayashi, Toshihiro Shioda, George Church, Pranam Chatterjee
The generation of germline cell types from human induced pluripotent stem cells (hiPSCs) represents a key milestone toward in vitro gametogenesis, which has the potential to transform reproductive medicine. Methods to recapitulate germline cell speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d320dd383bf6646ac1162e92d06ffe
https://doi.org/10.21203/rs.3.rs-2652895/v1
https://doi.org/10.21203/rs.3.rs-2652895/v1