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pro vyhledávání: '"Sophia Skoulikas"'
Autor:
Luca A Petruccelli, Daphné Dupéré-Richer, Filippa Pettersson, Hélène Retrouvey, Sophia Skoulikas, Wilson H Miller
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20987 (2011)
Histone deacetylase inhibitors (HDACi) are promising anti-cancer agents, however, their mechanisms of action remain unclear. In acute myeloid leukemia (AML) cells, HDACi have been reported to arrest growth and induce apoptosis. In this study, we eluc
Externí odkaz:
https://doaj.org/article/c47aa15086ee447286cb29df7ad14528
Autor:
Sophia Skoulikas, Wilson H. Miller, Filippa Pettersson, Daphné Dupéré-Richer, Helene Retrouvey, Luca A. Petruccelli
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20987 (2011)
PLoS ONE
PLoS ONE
Histone deacetylase inhibitors (HDACi) are promising anti-cancer agents, however, their mechanisms of action remain unclear. In acute myeloid leukemia (AML) cells, HDACi have been reported to arrest growth and induce apoptosis. In this study, we eluc
Autor:
Filippa Pettersson, Luca A. Petruccelli, Wilson H. Miller, Jonathan D. Licht, Kim L. Rice, Jessica N. Nichol, Sophia Skoulikas
Publikováno v:
Cancer Research. 71:2136-2136
Acute myeloid leukemias (AMLs) are often characterized by chromosomal translocations resulting in the expression of fusion proteins (FP). Some FP have been demonstrated to recruit histone deacetylases (HDACs) and repress the expression of DNA repair