Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sophia Semerdjieva"'
Autor:
Claire L Russell, Sophia Semerdjieva, Ruth M Empson, Brian M Austen, Philip W Beesley, Pavlos Alifragis
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43201 (2012)
It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42). However, the unde
Externí odkaz:
https://doaj.org/article/4125f04b5b7b43bbb03e4f158d5b869d
Autor:
Jonathan Hansen, Paul Fonarev, Barth D. Grant, Barry Shortt, Sukhdeep Singh, Elizabeth Smythe, Emma Maxwell, Sophia Semerdjieva, Giampietro Schiavo
Publikováno v:
The Journal of Cell Biology
Here we investigate the role of rab5 and its cognate exchange factors rabex-5 and hRME-6 in the regulation of AP2 uncoating from endocytic clathrin-coated vesicles (CCVs). In vitro, we show that the rate of AP2 uncoating from CCVs is dependent on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fabf0a0988e6d5b9ad18b9089beaf7
https://doi.org/10.1083/jcb.200806016
https://doi.org/10.1083/jcb.200806016
Publikováno v:
Biochemical Society Symposia. 72:65-70
Reversible phosphorylation has long been an attractive mechanism to control cycles of coat assembly and disassembly during clathrin-mediated endocytosis. Many of the coat proteins are phosphorylated in vivo and in vitro. Our work has focused on the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f75a5a4c04c39770599314dc3b598a8
https://doi.org/10.1042/bss0720065
https://doi.org/10.1042/bss0720065
Autor:
Victor Tarabykin, Sophia Semerdjieva, HH Abdul-Razak, Sharifah S. Salim, Pavlos Alifragis, Rafael J. Yáñez-Muñoz, Philip E. Chen
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology; Vol 33
Molecular and Cellular Biology; Vol 33
Regulation of the activity of N-methyl-d-aspartate receptors (NMDARs) at glutamatergic synapses is essential for certain forms of synaptic plasticity underlying learning and memory and is also associated with neurotoxicity and neurodegenerative disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880d58d6a8a2cc3eed7ab6ce69eef3f2
https://pubmed.ncbi.nlm.nih.gov/23382070
https://pubmed.ncbi.nlm.nih.gov/23382070
Autor:
Sophia Semerdjieva, Claire Russell, Pavlos Alifragis, Ruth M. Empson, Philip W. Beesley, Brian M. Austen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43201 (2012)
PLOSone
PLoS ONE
PLOSone
PLoS ONE
BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42). Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc22dbdd72f66bff0f75e983d41e8ab
http://europepmc.org/articles/PMC3419646?pdf=render
http://europepmc.org/articles/PMC3419646?pdf=render
Autor:
Russell, Claire L.1, Semerdjieva, Sophia1, Empson, Ruth M.1,2, Austen, Brian M.3, Beesley, Philip W.1, Alifragis, Pavlos1 pavlos.alifragis@rhul.ac.uk, Ferreira, Sergio T.4
Publikováno v:
PLoS ONE. Aug2012, Vol. 7 Issue 8, Special section p1-14. 14p.