Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Sophia Schedin, Weiss"'
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The COVID-19 pandemic prompted a refocus of health care resources to acute care which has impacted on the capacity of healthcare systems to conduct neurological surgeries. The elderly population has been shown to be particularly v
Externí odkaz:
https://doaj.org/article/62547f1d064843b8a9fffb447fc27b8d
Autor:
Michael Axenhus, Tosca Doeswijk, Per Nilsson, Anna Matton, Bengt Winblad, Lars Tjernberg, Sophia Schedin-Weiss
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3622 (2024)
At the time of diagnosis, Alzheimer’s disease (AD) patients already suffer from significant neuronal loss. The identification of proteins that influence disease progression before the onset of symptoms is thus an essential part of the development o
Externí odkaz:
https://doaj.org/article/479b6de432c24674bd3d9f8c306f85b7
Autor:
Anders Sandberg, Ernesto Berenjeno-Correa, Rosa Crespo Rodriguez, Michael Axenhus, Sophia Schedin Weiss, Kevin Batenburg, Jeroen J. M. Hoozemans, Lars O. Tjernberg, Wiep Scheper
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background In Alzheimer’s disease (AD), amyloid-β 1–42 (Aβ42) neurotoxicity stems mostly from its soluble oligomeric aggregates. Studies of such aggregates have been hampered by the lack of oligomer-specific research tools and their in
Externí odkaz:
https://doaj.org/article/cee0908148f64f599e9891ba7768079f
Autor:
Michael Axenhus, Sophia Schedin-Weiss, Lars Tjernberg, Anders Wimo, Maria Eriksdotter, Gustaf Bucht, Bengt Winblad
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Introduction The COVID-19 pandemic has caused large disruptions to healthcare systems. Refocus on COVID-19 related care might have contributed to indirect effects on other healthcare areas. Care focused on acute conditions have been negative
Externí odkaz:
https://doaj.org/article/3c66062851f646efb5c104422d25bae6
Autor:
Hazal Haytural, Rui Benfeitas, Sophia Schedin-Weiss, Erika Bereczki, Melinda Rezeli, Richard D. Unwin, Xusheng Wang, Eric B. Dammer, Erik C. B. Johnson, Nicholas T. Seyfried, Bengt Winblad, Betty M. Tijms, Pieter Jelle Visser, Susanne Frykman, Lars O. Tjernberg
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-11 (2021)
Abstract Mass spectrometry (MS)-based proteomics is a powerful tool to explore pathogenic changes of a disease in an unbiased manner and has been used extensively in Alzheimer disease (AD) research. Here, by performing a meta-analysis of high-quality
Externí odkaz:
https://doaj.org/article/d189ee05892c4b5e8df9e6a2031f9246
Autor:
Anna Sandebring-Matton, Michael Axenhus, Nenad Bogdanovic, Bengt Winblad, Sophia Schedin-Weiss, Per Nilsson, Lars O. Tjernberg
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Novel insights on proteins involved in Alzheimer’s disease (AD) are needed. Since multiple cell types and matrix components are altered in AD, bulk analysis of brain tissue maybe difficult to interpret. In the current study, we isolated pyramidal c
Externí odkaz:
https://doaj.org/article/b8e169d732ac4e29afd84eac3f2589c9
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 801 (2021)
Alzheimer’s disease (AD) is the most common type of dementia, contributing to 60–80% of cases. It is a neurodegenerative disease that usually starts symptomless in the first two to three decades and then propagates into a long-term, irreversible
Externí odkaz:
https://doaj.org/article/efa78d8b969c414188eaf504fc6db385
Publikováno v:
Biomolecules, Vol 11, Iss 6, p 858 (2021)
Proteomics—large-scale studies of proteins—has over the last decade gained an enormous interest for studies aimed at revealing proteins and pathways involved in disease. To fully understand biological and pathological processes it is crucial to a
Externí odkaz:
https://doaj.org/article/2abeed48cf2c4d58b5f2e348ba52179f
Autor:
Sophia Schedin-Weiss, Mitsuhiro Inoue, Lenka Hromadkova, Yasuhiro Teranishi, Natsuko Goto Yamamoto, Birgitta Wiehager, Nenad Bogdanovic, Bengt Winblad, Anna Sandebring-Matton, Susanne Frykman, Lars O. Tjernberg
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-19 (2017)
Abstract Background Increased levels of the pathogenic amyloid β-peptide (Aβ), released from its precursor by the transmembrane protease γ-secretase, are found in Alzheimer disease (AD) brains. Interestingly, monoamine oxidase B (MAO-B) activity i
Externí odkaz:
https://doaj.org/article/e013012247bd498c9c9baac88e3a9855
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4530 (2021)
Amyloid β-peptide (Aβ) oligomerization is believed to contribute to the neuronal dysfunction in Alzheimer disease (AD). Despite decades of research, many details of Aβ oligomerization in neurons still need to be revealed. Förster resonance energy
Externí odkaz:
https://doaj.org/article/7ba5e155251740e0a7c8ccfae24499e6