Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sophia Rowlston"'
Autor:
Luigi Grassi, Osagie G. Izuogu, Natasha A.N. Jorge, Denis Seyres, Mariona Bustamante, Frances Burden, Samantha Farrow, Neda Farahi, Fergal J. Martin, Adam Frankish, Jonathan M. Mudge, Myrto Kostadima, Romina Petersen, John J. Lambourne, Sophia Rowlston, Enca Martin-Rendon, Laura Clarke, Kate Downes, Xavier Estivill, Paul Flicek, Joost H.A. Martens, Marie-Laure Yaspo, Hendrik G. Stunnenberg, Willem H. Ouwehand, Fabio Passetti, Ernest Turro, Mattia Frontini
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
Transcriptional profiling of hematopoietic cell subpopulations has helped to characterize the developmental stages of the hematopoietic system and the molecular bases of malignant and non-malignant blood diseases. Previously, only the genes targeted
Externí odkaz:
https://doaj.org/article/fc260f918bfb4ac080d707f06026c2c3
Autor:
Dirk S. Paul, Andrew E. Teschendorff, Mary A.N. Dang, Robert Lowe, Mohammed I. Hawa, Simone Ecker, Huriya Beyan, Stephanie Cunningham, Alexandra R. Fouts, Anita Ramelius, Frances Burden, Samantha Farrow, Sophia Rowlston, Karola Rehnstrom, Mattia Frontini, Kate Downes, Stephan Busche, Warren A. Cheung, Bing Ge, Marie-Michelle Simon, David Bujold, Tony Kwan, Guillaume Bourque, Avik Datta, Ernesto Lowy, Laura Clarke, Paul Flicek, Emanuele Libertini, Simon Heath, Marta Gut, Ivo G Gut, Willem H. Ouwehand, Tomi Pastinen, Nicole Soranzo, Sabine E. Hofer, Beate Karges, Thomas Meissner, Bernhard O. Boehm, Corrado Cilio, Helena Elding Larsson, Åke Lernmark, Andrea K. Steck, Vardhman K. Rakyan, Stephan Beck, R. David Leslie
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The incidence of type 1 diabetes is increasing, potentially implicating non-genetic factors. Here the authors conduct an epigenome-wide association study in disease-discordant twins and find increased DNA methylation variability at genes associated w
Externí odkaz:
https://doaj.org/article/74847440186d44ba8513e31e9862b708
Autor:
Natasha Andressa Nogueira Jorge, Jonathan M. Mudge, Mattia Frontini, Myrto Kostadima, Osagie G. Izuogu, Enca Martin-Rendon, Hendrik G. Stunnenberg, Romina Petersen, Denis Seyres, Xavier Estivill, Paul Flicek, Luigi Grassi, Samantha Farrow, Fabio Passetti, John J. Lambourne, Willem H. Ouwehand, Neda Farahi, Frances Burden, Adam Frankish, Sophia Rowlston, Joost H.A. Martens, Marie-Laure Yaspo, Kate Downes, Mariona Bustamante, Laura Clarke, Ernest Turro, Fergal J. Martin
Publikováno v:
Haematologica
Transcriptional profiling of hematopoietic cell subpopulations has helped to characterize the developmental stages of the hematopoietic system and the molecular bases of malignant and non-malignant blood diseases. Previously, only the genes targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a980f76dbddd9b34e0b2030d7e08cec
Autor:
Luigi Grassi, N. A. Jeorge, Kate Downes, Frances Burden, Paul Flicek, Xavier Estivill, John J. Lambourne, Neda Farahi, Henk Stunnenberg, Willem H. Ouwehand, Romina Petersen, Denis Seyres, Fergal J. Martin, Fabio Passetti, Adam Frankish, Sophia Rowlston, Laura Clarke, Joost H.A. Martens, S. Farrow, Myrto Kostadima, Osagie G. Izuogu, Ernest Turro, Marie-Laure Yaspo, Jonathan M. Mudge, Mariona Bustamante, Mattia Frontini, Enca Martin-Rendon
Transcriptional profiling of hematopoietic cell subpopulations has helped characterize the developmental stages of the hematopoietic system and the molecular basis of malignant and non-malignant blood diseases for the past three decades. The introduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7193449f322457c6321bba401e731fa2
Autor:
Ricardo C. Ferreira, Oliver S. Burren, Xaquin Castro Dopico, John J. Lambourne, Kate Downes, Steven W. Wingett, Mikhail Spivakov, Daniel B. Rainbow, Antony J. Cutler, Ellen Schofield, Linda S. Wicker, Nicholas J. Cooper, Jonathan Cairns, Frances Burden, Richard M.R. Coulson, Mattia Frontini, John A. Todd, Sophia Rowlston, Chris Wallace, Biola-Maria Javierre, Willem H. Ouwehand, Arcadio Rubio García, Peter Fraser
Publikováno v:
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
BackgroundAutoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4+ T cells. Linking such regulatory regions to gene promoters in disease-relevant cell contexts facilitates identification
Autor:
Tomi Pastinen, Guillaume Bourque, Paul Flicek, Bing Ge, Farzin Pourfarzad, Frederik Otzen Bagger, Simone Ecker, Lu Chen, Augusto Rendon, Stephen Watt, John J. Lambourne, Heather Elding, Mattia Frontini, Nicole Soranzo, Karola Rehnström, Roderic Guigó, Marie-Laure Yaspo, Willem H. Ouwehand, Frances Burden, Avik Datta, Dirk S. Paul, Kim Berentsen, Filomena Matarese, Xiaojian Shao, Laura Clarke, Alice L. Mann, Hendrik G. Stunnenberg, Francesco Paolo Casale, Stephan Busche, Vyacheslav Amstislavskiy, Matthew T. Maurano, Warren A. Cheung, Shu-Huang Chen, Marc Sultan, Emmanouil T. Dermitzakis, Thomas Risch, Eva M. Janssen-Megens, Lorenzo Bomba, Diego Garrido-Martín, Nilofar Sharifi, Tony Kwan, David Bujold, Louella Vasquez, Klaudia Walter, Bowon Kim, Stylianos E. Antonarakis, Irina Colgiu, Marie-Michelle Simon, John A. Morris, Ying Yan, Daniel Rico, Oliver Stegle, Stephan Beck, Vera Pancaldi, Steven P. Wilder, Ernesto Lowy, Hans Lehrach, José M. Fernández, Shuang-Yin Wang, Kousik Kundu, Daniel Mead, Sofie Ashford, Maxime Caron, Oliver Delaneau, Sophia Rowlston, Joost H.A. Martens, Adriana Redensek, Samantha Farrow, Valentina Iotchkova, Kate Downes, Amit Mandoli, David J. Richardson, Alfonso Valencia, Ehsan Habibi, Cornelis A. Albers, Taco W. Kuijpers
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Cell
Cell, 167(5), 1398-1414.e24. Cell Press
Cell, Vol. 167, No 5 (2016) pp. 1398-1414.e24
Cell, 167, 1398-1414.e24
Cell, 167, 5, pp. 1398-1414.e24
instname
Cell
Cell, 167(5), 1398-1414.e24. Cell Press
Cell, Vol. 167, No 5 (2016) pp. 1398-1414.e24
Cell, 167, 1398-1414.e24
Cell, 167, 5, pp. 1398-1414.e24
Summary Characterizing the multifaceted contribution of genetic and epigenetic factors to disease phenotypes is a major challenge in human genetics and medicine. We carried out high-resolution genetic, epigenetic, and transcriptomic profiling in thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439d7495a9cb321732a8a2cefe5ea4d8
http://hdl.handle.net/10230/28353
http://hdl.handle.net/10230/28353