Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Sophia Ran"'
Autor:
Lisa Volk-Draper, Shaswati Athaiya, Maria Espinosa Gonzalez, Nihit Bhattarai, Andrew Wilber, Sophia Ran
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0298465 (2024)
Lymphangiogenesis is induced by local pro-lymphatic growth factors and bone marrow (BM)-derived myeloid-lymphatic endothelial cell progenitors (M-LECP). We previously showed that M-LECP play a significant role in lymphangiogenesis and lymph node meta
Externí odkaz:
https://doaj.org/article/7cb2bd12fe8d4454b261745dd9d3d13d
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 823 (2022)
Reactive oxygen species (ROS) can be beneficial or harmful in health and disease. While low levels of ROS serve as signaling molecules to regulate vascular tone and the growth and proliferation of endothelial cells, elevated levels of ROS contribute
Externí odkaz:
https://doaj.org/article/7f2eed5006544138acf933765c36dea6
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179257 (2017)
Myeloid-derived lymphatic endothelial cells (M-LECP) are induced by inflammation and play an important role in adult lymphangiogenesis. However, the mechanisms driving M-LECP differentiation are currently unclear. We previously showed that activation
Externí odkaz:
https://doaj.org/article/10916262055046fc805b54ac26d4bad3
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 4, Pp 327-338 (2011)
Introduction Patients with metastatic disease are considered incurable. We previously showed that nabpaclitaxel (nanoparticle albumin-embedded paclitaxel) combined with anti-vascular endothelial growth factor A (VEGF-A) antibody, bevacizumab, eradica
Externí odkaz:
https://doaj.org/article/6eabd8898199407cb0ad7a587ba3b28c
Autor:
Lisa D. Volk, Michael J. Flister, Christopher M. Bivens, Alan Stutzman, Neil Desai, Vuong Trieu, Sophia Ran
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 6, Pp 613-623 (2008)
Nab-paclitaxel is an albumin-bound 130-nm particle form of paclitaxel that has shown an improved efficacy in experimental tumor models and clinical studies compared with solvent-based paclitaxel. Anti–vascular endothelial growth factor A (VEGF-A) a
Externí odkaz:
https://doaj.org/article/3ced551fc7fc4bcc973831ee7cc5f472
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 5, Pp 486-496 (2005)
VEGF121/rGel, a fusion protein composed of the growth factor VEGF121 and the recombinant toxin gelonin (rGel), targets the tumor neovasculature and exerts impressive cytotoxic effects by inhibiting protein synthesis. We evaluated the effect of VEGF12
Externí odkaz:
https://doaj.org/article/3d42c42e7ea04d55acdce11799508e0d
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 4, Pp 297-307 (2003)
We generated a panel of eight rat IgG2a monoclonal antibodies with high affinity for mouse VEGFR2 (KDR/Flk-1), the main receptor that mediates the angiogenic effect of VEGF-A. The antibodies (termed RAFL, Rat Anti Flk) bound to dividing endothelial c
Externí odkaz:
https://doaj.org/article/9cbee419a96347049c17438200ab9b9d
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 4, Pp 308-318 (2003)
Tumor oxygenation has long been recognized as a significant factor influencing cancer therapy. We recently established a novel magnetic resonance in vivo approach to measuring regional tumor oxygen tension, FREDOM (Fluorocarbon Relaxometry Using Echo
Externí odkaz:
https://doaj.org/article/86343f412d034df7aa3684eb3528fb28
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31794 (2012)
Macrophage-derived lymphatic endothelial cell progenitors (M-LECPs) contribute to new lymphatic vessel formation, but the mechanisms regulating their differentiation, recruitment, and function are poorly understood. Detailed characterization of M-LEC
Externí odkaz:
https://doaj.org/article/31a7244e79f148a3b65d5bc9ae5a2d9e
Autor:
Kanako Hayashi, Kounosuke Watabe, Laurent Brard, Norihiro Sugino, Mary E. McAsey, James A. MacLean, Hiroshi Okuda, Sophia Ran, Mandy L. King, Shin Yoshioka
PDF file - 2.5MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b2130b691293b0220e0e4a3d3c0d5b
https://doi.org/10.1158/1541-7786.22517880
https://doi.org/10.1158/1541-7786.22517880
