Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sophia R. Zhao"'
Autor:
David M. Wu, Xuke Ji, Maryna V. Ivanchenko, Michelle Chung, Mary Piper, Parimal Rana, Sean K. Wang, Yunlu Xue, Emma West, Sophia R. Zhao, Hongbin Xu, Marcelo Cicconet, Wenjun Xiong, Constance L. Cepko
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Nrf2, a transcription factor that regulates the response to oxidative stress, has been shown to rescue cone photoreceptors and slow vision loss in mouse models of retinal degeneration (rd). The retinal pigment epithelium (RPE) is damaged in these mod
Externí odkaz:
https://doaj.org/article/66ed3b635a034060a47e1f54e323c711
Autor:
Wenjun, Xiong, David M, Wu, Yunlu, Xue, Sean K, Wang, Michelle J, Chung, Xuke, Ji, Parimal, Rana, Sophia R, Zhao, Shuyi, Mai, Constance L, Cepko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Adeno-associated viral (AAV) gene therapy is becoming an important therapeutic modality, especially for ocular diseases, due to its efficiency of gene delivery and relative lack of pathogenicity. However, AAV sometimes can cause inflamma
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 21(1)
Known as a uniquely regenerative tissue, the liver shows a remarkable capacity to heal without scarring after many types of acute injury. In contrast, during chronic liver disease, the liver responds with fibrosis, which can progress to cirrhosis and