Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sophia P. Hirakis"'
Autor:
Sophia P Hirakis, Britton Warren Boras, Lane W Votapka, Robert Dean Malmstrom, Andrew D McCulloch, Rommie E Amaro
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
The goal of multiscale modeling in biology is to use structurally based physico-chemical models to integrate across temporal and spatial scales of biology and thereby improve mechanistic understanding of, for example, how a single mutation can alter
Externí odkaz:
https://doaj.org/article/0fb01e8cf24d4f469d2801a68478530b
Autor:
Sophia P. Hirakis, James V. McCullagh
Publikováno v:
Journal of Chemical Education. 94:1347-1351
This synthesis of ethyl 6-acetoxyhexanoate (Berryflor) is designed as an experiment for use in a second-year organic chemistry course focusing on the synthesis and reaction of esters. The compound is described as having a raspberry-like odor with jas
Autor:
Andrew D. McCulloch, Rommie E. Amaro, Sophia P. Hirakis, Abigail E. Teitgen, Alexandre B. Duclos, Michael Regnier, Kimberly J. McCabe
Publikováno v:
Biophysical Journal. 118:260a
Publikováno v:
Biochemistry. 56(30)
We identify a previously unresolved, unrecognized, and highly stable conformation of the protein kinase A (PKA) regulatory subunit RIα. This conformation, which we term the “Flipback” structure, bridges conflicting characteristics in crystallogr
Autor:
Cosmo Z. Buffalo, Adrian J. Bahn-Suh, Sophia P. Hirakis, Tapan Biswas, Rommie E. Amaro, Victor Nizet, Partho Ghosh
Publikováno v:
Nature Microbiology. 2
Autor:
Rommie E. Amaro, Cosmo Z. Buffalo, Sophia P. Hirakis, Tapan Biswas, Partho Ghosh, Adrian J Bahn-Suh, Victor Nizet
Publikováno v:
Nature microbiology, vol 1, iss 11
Buffalo, CZ; Bahn-Suh, AJ; Hirakis, SP; Biswas, T; Amaro, RE; Nizet, V; et al.(2016). Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nature Microbiology, 1(11). doi: 10.1038/NMICROBIOL.2016.155. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0540k3rh
Nature microbiology
Buffalo, CZ; Bahn-Suh, AJ; Hirakis, SP; Biswas, T; Amaro, RE; Nizet, V; et al.(2016). Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nature Microbiology, 1(11). doi: 10.1038/NMICROBIOL.2016.155. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0540k3rh
Nature microbiology
No vaccine exists against group A Streptococcus (GAS), a leading cause of worldwide morbidity and mortality. A severe hurdle is the hypervariability of its major antigen, the M protein, with >200 different M types known. Neutralizing antibodies typic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e78e6cdafd72d8efc52f03a1f5cfbb1
https://escholarship.org/uc/item/0540k3rh
https://escholarship.org/uc/item/0540k3rh
Publikováno v:
Biophysical Journal. 114:118a
Publikováno v:
Biophysical Journal. 112:484a