Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sophia M. Hirsch"'
Publikováno v:
Journal of Cell Biology. 221
Contractile ring constriction during cytokinesis is thought to compact central spindle microtubules to form the midbody, an antiparallel microtubule bundle at the intercellular bridge. In Caenorhabditis elegans, central spindle microtubule assembly r
Autor:
Shawn N. Jordan, Yelena Zhuravlev, Mimi Shirasu-Hiza, Julie C. Canman, Julien Dumont, Sophia M. Hirsch
Publikováno v:
Molecular Biology of the Cell
The roles of the Rho-family GAP CYK-4 and small GTPase Rac during cytokinesis are examined in Caenorhabditis elegans embryos. CYK-4 opposes Rac (and potentially Cdc42) activity during cytokinesis. There is no evidence that CYK-4 is upstream of Rho ac
Autor:
Andrew C. Kummel, Julie C. Canman, Adrian Garcia Badaracco, Sophia M. Hirsch, Mimi Shirasu-Hiza, Tim Davies, Jun Hong Park, Julien Dumont, Sriramkumar Sundaramoorthy
Publikováno v:
ACS Applied Materials & Interfaces. 9:7929-7940
The combination of near infrared (NIR) and visible wavelengths in light microscopy for biological studies is increasingly common. For example, many fields of biology are developing the use of NIR for optogenetics, in which an NIR laser induces a chan
Autor:
Mimi Shirasu-Hiza, Jennifer C. Waters, Sophia M. Hirsch, Tim Davies, Julie C. Canman, Sriramkumar Sundaramoorthy, Yelena Zhuravlev, Julien Dumont
Publikováno v:
Nature methods
Nature Methods
Nature Methods, Nature Publishing Group, 2018, 15 (11), pp.921-923. ⟨10.1038/s41592-018-0168-y⟩
Nature Methods
Nature Methods, Nature Publishing Group, 2018, 15 (11), pp.921-923. ⟨10.1038/s41592-018-0168-y⟩
FLIRT (Fast Local InfraRed Thermogenetics) is a microscopy-based technology to locally and reversibly manipulate protein function during cellular behaviors while simultaneously monitoring the effects in vivo. FLIRT locally inactivates fast-acting tem