Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sophia M Raefsky"'
Autor:
Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattson
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196223 (2018)
Bhlhe40 is a transcription factor that is highly expressed in the hippocampus; however, its role in neuronal function is not well understood. Here, we used Bhlhe40 null mice on a congenic C57Bl6/J background (Bhlhe40 KO) to investigate the impact of
Externí odkaz:
https://doaj.org/article/29b6816178af4788abed0fca4328ae15
Autor:
Yong Liu, Aiwu Cheng, Yu-Jiao Li, Ying Yang, Yuki Kishimoto, Shi Zhang, Yue Wang, Ruiqian Wan, Sophia M. Raefsky, Daoyuan Lu, Takashi Saito, Takaomi Saido, Jian Zhu, Long-Jun Wu, Mark P. Mattson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Intermittent fasting has been shown to have beneficial effects on hippocampal function in rodents, but the underlying mechanism is not fully understood. Here the authors show that the mitochondrial protein SIRT3 contributes to the beneficial cognitiv
Externí odkaz:
https://doaj.org/article/cbdb31d971724064a184d9a5ad197134
Autor:
Archana Podury, Sophia M. Raefsky, Lucy Dodakian, Liam McCafferty, Vu Le, Alison McKenzie, Jill See, Robert J. Zhou, Thalia Nguyen, Benjamin Vanderschelden, Gene Wong, Laila Nazarzai, Jutta Heckhausen, Steven C. Cramer, Amar Dhand
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objective: Telerehabilitation (TR) is now, in the context of COVID-19, more clinically relevant than ever as a major source of outpatient care. The social network of a patient is a critical yet understudied factor in the success of TR that may influe
Externí odkaz:
https://doaj.org/article/6b547692f50044c79705315a8e0a8c1c
Autor:
Steven C. Cramer, Lucy Dodakian, Vu Le, Alison McKenzie, Jill See, Renee Augsburger, Robert J. Zhou, Sophia M. Raefsky, Thalia Nguyen, Benjamin Vanderschelden, Gene Wong, Daniel Bandak, Laila Nazarzai, Amar Dhand, Walt Scacchi, Jutta Heckhausen
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Introduction: High doses of activity-based rehabilitation therapy improve outcomes after stroke, but many patients do not receive this for various reasons such as poor access, transportation difficulties, and low compliance. Home-based telerehabilita
Externí odkaz:
https://doaj.org/article/88861ff2ced540fa8c78504ea914662b
Autor:
Caleb L. Shumway, Laura R. Cuevas, Emily Frisch, Sophia M. Raefsky, Charlotte Gore, Austin Crochetiere, Param Bhatter, Kaosoluchi Enendu, Louie Cao, Andrew W. Browne
Publikováno v:
Telemed J E Health
Background: Visual impairment, specifically anterior segment pathology, presents a significant burden of disease in the world. Introduction: Inexpensive tools are necessary to improve eye health of residents in developing countries where care is diff
Autor:
Ronald Sahyouni, Khodayar Goshtasbi, Hossein Mahboubi, Edward C. Kuan, Sophia M. Raefsky, Frank P.K. Hsu, Gilbert Cadena, Arash Abiri
Publikováno v:
World Neurosurgery. 132:33-40
Background Pituitary apoplexy (PA) can manifest with visual and endocrine defects. The literature lacks strong support for either surgical or conservative management with respect to symptomatic improvement of these deficits. This meta-analysis compar
Autor:
Alison McKenzie, Sophia M. Raefsky, Thalia Nguyen, Elizabeth Woytowicz, Robert J. Zhou, Walt Scacchi, Vu Le, Benjamin Vanderschelden, Lucy Dodakian, Steven C. Cramer, Jutta Heckhausen, Gene Wong, Danial Bandak, Renee Augsburger, Laila Nazarzai, Amar Dhand, Jill See
Publikováno v:
Stroke. 51
Introduction: High doses of activity-based rehabilitation therapy help but many patients do not receive this, e.g., due to access, cost, and low compliance. Home-based telerehabilitation (TR) can address these issues. A prior study found 6 weeks of T
Autor:
Erik D. Pollock, Paul H. Axelsen, Sophia M. Raefsky, Mark P. Mattson, Mikhail S. Shchepinov, Ginger L. Milne, Ran Furman
Publikováno v:
Neurobiology of Aging. 66:165-176
Alzheimer's disease (AD) involves progressive deposition of amyloid β-peptide (Aβ), synapse loss, and neuronal death, which occur in brain regions critical for learning and memory. Considerable evidence suggests that lipid peroxidation contributes
Autor:
Mark P. Mattson, Sophia M. Raefsky
Publikováno v:
Free Radical Biology and Medicine. 102:203-216
An important concept in neurobiology is “neurons that fire together, wire together” which means that the formation and maintenance of synapses is promoted by activation of those synapses. Very similar to the effects of the stress of exercise on m
Autor:
Long Jun Wu, Aiwu Cheng, Sophia M. Raefsky, Yue Wang, Yong Liu, Daoyuan Lu, Ruiqian Wan, Yuki Kishimoto, Takashi Saito, Ying Yang, Mark P. Mattson, Shi Zhang, Takaomi C. Saido, Yu Jiao Li, Jian Zhu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Intermittent food deprivation (fasting, IF) improves mood and cognition and protects neurons against excitotoxic degeneration in animal models of epilepsy and Alzheimer’s disease (AD). The mechanisms by which neuronal networks adapt to IF and how s