Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sophia Hartung"'
Publikováno v:
Current Opinion in Biotechnology. 23:89-95
The vital nature of metal uptake and balance in biology is evident in the highly evolved strategies to facilitate metal homeostasis in all three domains of life. Several decades of study on metals and metalloproteins have revealed numerous essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d04bb602d22a989ab89c68e858218f
https://doi.org/10.1016/j.copbio.2011.11.005
https://doi.org/10.1016/j.copbio.2011.11.005
Autor:
Lisa Craig, Sophia Hartung, Subramaniapillai Kolappan, David S. Shin, Timothy I. Wood, John A. Tainer, Andrew S. Arvai
Publikováno v:
Journal of Biological Chemistry. 286:44254-44265
Pilin proteins assemble into Type IV pili (T4P), surface-displayed bacterial filaments with virulence functions including motility, attachment, transformation, immune escape, and colony formation. However, challenges in crystallizing full-length fibe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083f1bb7eeb47a0b1b2fb0629450ef90
https://doi.org/10.1074/jbc.m111.297242
https://doi.org/10.1074/jbc.m111.297242
Publikováno v:
Biochemical Journal. 437:43-52
Microbial motility frequently depends on flagella or type IV pili. Using recently developed archaeal genetic tools, archaeal flagella and its assembly machinery have been identified. Archaeal flagella are functionally similar to bacterial flagella an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60a8a84e65ea74a43a5109780166df0
https://doi.org/10.1042/bj20110410
https://doi.org/10.1042/bj20110410
Autor:
Sophia Hartung, Karl-Peter Hopfner
Publikováno v:
Biochemical Society Transactions. 37:83-87
The RNA exosome is a multisubunit exonuclease involved in numerous RNA maturation and degradation processes. Exosomes are found in eukaryotes and archaea and are related to bacterial polynucleotide phosphorylates. Over the past years structural and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098f78ca5d979cfc118104562b3880a6
https://doi.org/10.1042/bst0370083
https://doi.org/10.1042/bst0370083
Publikováno v:
ResearcherID
RNA exosomes are large multi-subunit protein complexes involved in controlled and processive 3' to 5' RNA degradation. Exosomes form large molecular chambers and harbor multiple nuclease sites as well as RNA binding regions. This makes a quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbbb2231be203adee633762159094dd
https://pubmed.ncbi.nlm.nih.gov/21282980
https://pubmed.ncbi.nlm.nih.gov/21282980
Autor:
Karl-Peter Hopfner, Sophia Hartung
Publikováno v:
Nucleic Acids and Molecular Biology ISBN: 9783642210778
RNA exosomes are large multimeric 3′-5′ exo- and endonucleases found in eukaryotes and many archaeal species. They represent the central RNA 3′-end processing factor and are implicated in processing, quality control, and turnover of both coding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e50c57808d33daecae3f8c375425463a
https://doi.org/10.1007/978-3-642-21078-5_9
https://doi.org/10.1007/978-3-642-21078-5_9
Publikováno v:
Nano Letters
Molecular motors have inspired many avenues of research for nanotechnology but most molecular motors studied so far allow only unidirectional movement. The archaeal RNA-exosome is a reversible motor that can either polymerize or degrade an RNA strand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37942f8ca105629465900e50e34ee5bf
https://pubmed.ncbi.nlm.nih.gov/21082788
https://pubmed.ncbi.nlm.nih.gov/21082788
Publikováno v:
Nucleic Acids Research
RNA exosomes are large multisubunit assemblies involved in controlled RNA processing. The archaeal exosome possesses a heterohexameric processing chamber with three RNase-PH-like active sites, capped by Rrp4- or Csl4-type subunits containing RNA-bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cf80b5665b01e6353be900463bdbed
https://pubmed.ncbi.nlm.nih.gov/20392821
https://pubmed.ncbi.nlm.nih.gov/20392821
Publikováno v:
Molecular cell. 30(2)
To reveal mechanisms of DNA damage checkpoint initiation, we structurally and biochemically analyzed DisA, a protein that controls a Bacillus subtilis sporulation checkpoint in response to DNA double-strand breaks. We find that DisA forms a large oct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0b263ea19f089e8d22aef050039b76
https://pubmed.ncbi.nlm.nih.gov/18439896
https://pubmed.ncbi.nlm.nih.gov/18439896
Autor:
Karl-Peter Hopfner, Sophia Hartung
Publikováno v:
EMBO reports. 8(5)
The correct processing, quality control and turnover of cellular RNA molecules is crucial to many aspects of cell physiology. The exosome—a large molecular assembly with exoribonuclease activity—has emerged as a crucial component in many, if not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a03db3ee57376583b7443d333700025
https://pubmed.ncbi.nlm.nih.gov/17380186
https://pubmed.ncbi.nlm.nih.gov/17380186