Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sophia Engelhard"'
Autor:
Sophia Engelhard, Montserrat Estruch, Shuyu Qin, Christoph A. Engelhard, Francisco G. Rodriguez-Gonzalez, Martine Drilsvik, Javier Martin-Gonzalez, Jeng-Wei Lu, David Bryder, Claus Nerlov, Joachim Weischenfeldt, Kristian Reckzeh, Kim Theilgaard-Mönch
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114475- (2024)
Summary: Endomucin (EMCN) currently represents the only hematopoietic stem cell (HSC) marker expressed by both murine and human HSCs. Here, we report that EMCN+ long-term repopulating HSCs (LT-HSCs; CD150+CD48−LSK) have a higher long-term multi-lin
Externí odkaz:
https://doaj.org/article/3dfc405563e042acaabd1378d8d20651
Autor:
Kim Theilgaard-Mönch, Thomas Helleday, Ulrika Warpman Berglund, Sophia Engelhard, Camilla Vittori, Kumar Sanjiv, Kristian Reckzeh, Montserrat Estruch, Anders Centio
Currently, the majority of patients with acute myeloid leukemia (AML) still die of their disease due to primary resistance or relapse toward conventional reactive oxygen species (ROS)- and DNA damage–inducing chemotherapy regimens. Herein, we explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d214d6aedb84973092fd78ecb7c18fe
https://doi.org/10.1158/1535-7163.c.6543309
https://doi.org/10.1158/1535-7163.c.6543309
Autor:
Kim Theilgaard-Mönch, Thomas Helleday, Ulrika Warpman Berglund, Sophia Engelhard, Camilla Vittori, Kumar Sanjiv, Kristian Reckzeh, Montserrat Estruch, Anders Centio
Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d2b851cc283c27330d8dc9028e56f9
https://doi.org/10.1158/1535-7163.22522218.v1
https://doi.org/10.1158/1535-7163.22522218.v1
Autor:
Kim Theilgaard-Mönch, Montserrat Estruch, Kyoung-Jae Won, Bo T. Porse, Camilla Vittori, Sophia Engelhard, Kristian Reckzeh, Ling Zhao, Mina Ali, Anders Centio, Paul P. Liu
Publikováno v:
Leukemia. 35:2030-2042
Most AML patients exhibit mutational activation of the PI3K/AKT signaling pathway, which promotes downstream effects including growth, survival, DNA repair, and resistance to chemotherapy. Herein we demonstrate that the inv(16)/KITD816Y AML mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd38e2dd3254fc60d89131a62e693cd
https://doi.org/10.1038/s41375-020-01094-0
https://doi.org/10.1038/s41375-020-01094-0
Autor:
Anders Centio, Montserrat Estruch, Kristian Reckzeh, Kumar Sanjiv, Camilla Vittori, Sophia Engelhard, Ulrika Warpman Berglund, Thomas Helleday, Kim Theilgaard-Mönch
Publikováno v:
Molecular cancer therapeutics. 21(5)
Currently, the majority of patients with acute myeloid leukemia (AML) still die of their disease due to primary resistance or relapse toward conventional reactive oxygen species (ROS)- and DNA damage–inducing chemotherapy regimens. Herein, we explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5b21f75802aaee0a6034838a2fae14
https://pubmed.ncbi.nlm.nih.gov/35247918
https://pubmed.ncbi.nlm.nih.gov/35247918
Autor:
Muhnnad Alkassar, Sophia Engelhardt, Tariq Abu-Tair, Efren Ojeda, Philipp C. Treffer, Michael Weyand, Oliver Rompel
Publikováno v:
Diagnostics, Vol 13, Iss 20, p 3162 (2023)
This study investigates the crucial factors influencing the end-systolic and end-diastolic volumes in MRI volumetry and their direct effects on the derived functional parameters. Through the simultaneous acquisition of 2D-cine and 3D whole-heart slic
Externí odkaz:
https://doaj.org/article/b4f0765637e244dea9fecfe687ec7786
Publikováno v:
Soil Security, Vol 6, Iss , Pp 100048- (2022)
We set out in this work to create a suite of 3D-like digital soil attribute maps for a research farming enterprise situated in the South Eastern Agricultural Zone of NSW, Australia. These digital maps come about because of a reconnaissance soil surve
Externí odkaz:
https://doaj.org/article/7e846183e3e94e8da742bb3bfd69af95