Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sophia Ceder"'
Autor:
Anderson Daniel Ramos, Ying Yu Liang, Olga Surova, Smaranda Bacanu, Marc-Antoine Gerault, Tamoghna Mandal, Sophia Ceder, Anette Langebäck, Albin Österroos, George A. Ward, Jonas Bergh, Klas G. Wiman, Sören Lehmann, Nayana Prabhu, Sara Lööf, Pär Nordlund
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114784- (2024)
Summary: Cellular phenotypes of apoptosis, as well as the activation of apoptosis caspase cascades, are well described. However, sequences and locations of early biochemical effector events after apoptosis initiation are still only partly understood.
Externí odkaz:
https://doaj.org/article/52b21ee609b64646a145af27d421b87c
Autor:
Sophia Ceder, Sofi E. Eriksson, Ying Yu Liang, Emarndeena H. Cheteh, Si Min Zhang, Kenji M. Fujihara, Julie Bianchi, Vladimir J. N. Bykov, Lars Abrahmsen, Nicholas J. Clemons, Pär Nordlund, Sean G. Rudd, Klas G. Wiman
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-10 (2021)
Abstract Asparaginase depletes extracellular asparagine in the blood and is an important treatment for acute lymphoblastic leukemia (ALL) due to asparagine auxotrophy of ALL blasts. Unfortunately, resistance occurs and has been linked to expression o
Externí odkaz:
https://doaj.org/article/b2b5eed6ca834936815c57813c137b8e
Autor:
Sophia Ceder, Sofi E Eriksson, Emarndeena H Cheteh, Swati Dawar, Mariana Corrales Benitez, Vladimir J N Bykov, Kenji M Fujihara, Mélodie Grandin, Xiaodun Li, Susanne Ramm, Corina Behrenbruch, Kaylene J Simpson, Frédéric Hollande, Lars Abrahmsen, Nicholas J Clemons, Klas G Wiman
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-20 (2020)
Abstract The tumor suppressor gene TP53 is the most frequently mutated gene in cancer. The compound APR‐246 (PRIMA‐1Met/Eprenetapopt) is converted to methylene quinuclidinone (MQ) that targets mutant p53 protein and perturbs cellular antioxidant
Externí odkaz:
https://doaj.org/article/ad163b956af24ac198adeee8afcb4f6a
Autor:
Sophia Ceder, Sofi E. Eriksson, Ying Yu Liang, Emarndeena H. Cheteh, Si Min Zhang, Kenji M. Fujihara, Julie Bianchi, Vladimir J. N. Bykov, Lars Abrahmsen, Nicholas J. Clemons, Pär Nordlund, Sean G. Rudd, Klas G. Wiman
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7a30218a8b2c440c80e8a3b947cee01f
Autor:
Klas G. Wiman, Lars Egevad, Martin Augsten, Sophia Ceder, Julie Bianchi, Arne Östman, Victoria Sarne, Helene Rundqvist, Emarndeena H Cheteh
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-14 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-14 (2020)
Cancer-associated fibroblasts (CAFs) promote tumor growth and progression, and increase drug resistance through several mechanisms. We have investigated the effect of CAFs on the p53 response to doxorubicin in prostate cancer cells. We show that CAFs
Autor:
Kenji M Fujihara, Kaylene J. Simpson, Nicholas J Clemons, Sofi E. Eriksson, Swati Dawar, Corina Behrenbruch, Klas G. Wiman, Sophia Ceder, Frédéric Hollande, Mariana Corrales Benitez, Mélodie Grandin, Xiaodun Li, Lars Abrahmsén, Susanne Ramm, Emarndeena H Cheteh, Vladimir J.N. Bykov
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
The tumor suppressor gene TP53 is the most frequently mutated gene in cancer. The compound APR‐246 (PRIMA‐1Met/Eprenetapopt) is converted to methylene quinuclidinone (MQ) that targets mutant p53 protein and perturbs cellular antioxidant balance.
Autor:
George E. Baltatzis, Sophia Ceder, Dorothea Rutishauser, Theocharis Panaretakis, Theodoros Foukakis, Ioulia Vardaki
Publikováno v:
Oncotarget
// Ioulia Vardaki 1 , Sophia Ceder 1 , Dorothea Rutishauser 2, 3 , George Baltatzis 4 , Theodoros Foukakis 1 , Theocharis Panaretakis 1 1 Department of Oncology-Pathology, Cancer Centrum Karolinska, Karolinska Institutet and University Hospital, Stoc
Autor:
Moritz Krall, Olga Axell, Klas G. Wiman, Pedram Kharaziha, Sophia Ceder, Sonia Lain, Svetlana Bajalica-Lagercrantz, Stefanie Böhm, Emma Tham, Åke Borg, Omid Fotouhi, Catharina Larsson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70560645b28dac89480e442c8ccda275
https://doi.org/10.1111/cge.13564/v2/response1
https://doi.org/10.1111/cge.13564/v2/response1
Publikováno v:
Journal of molecular cell biology. 11(4)
The TP53 tumor suppressor gene encodes a DNA-binding transcription factor that regulates multiple cellular processes including cell growth and cell death. The ability of p53 to bind to DNA and activate transcription is tightly regulated by post-trans
Autor:
Moritz Krall, Åke Borg, Catharina Larsson, Olga Axell, Emma Tham, Stefanie Böhm, Omid Fotouhi, Svetlana Bajalica-Lagercrantz, Sophia Ceder, Pedram Kharaziha, Sonia Lain, Klas G. Wiman
Publikováno v:
Clinical genetics. 96(3)
Pathogenic germline TP53 variants predispose to a wide range of early onset cancers, often recognized as the Li-Fraumeni syndrome (LFS). They are also identified in 1% of families with hereditary breast cancer (HrBC) that do not fulfill the criteria