Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sophia C. Monkman"'
Publikováno v:
Pharmacogenetics. 1:33-41
A randomly selected population of 73 volunteers, together with 22 previously established poor metabolisers of debrisoquine, were phenotyped for their ability to 4-hydroxylate debrisoquine and were also analysed for a number of mutations in the CYP2D6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6af7b1b7a020b3480772324384d036
https://doi.org/10.1097/00008571-199110000-00006
https://doi.org/10.1097/00008571-199110000-00006
Publikováno v:
Journal of Clinical Periodontology. 21:281-283
Amlodipine is a calcium channel blocker used in the management of angina and hypertension. We report 3 cases of gingival overgrowth in adult dentate patients associated with chronic usage of this drug. Gingival changes occurred within 3 months of dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c35f80518f2caac08fb24ef6917a78
https://doi.org/10.1111/j.1600-051x.1994.tb00318.x
https://doi.org/10.1111/j.1600-051x.1994.tb00318.x
Autor:
J. M. Thomason, Sophia C. Monkman, Janice S. Ellis, J.R. Idle, S. Cholerton, Robin A. Seymour
Publikováno v:
Journal of chromatography. B, Biomedical applications. 678(2)
This paper describes an automated capillary gas chromatographic method for the determination of amlodipine in plasma, and in sub-microlitre volumes of gingival crevicular fluid (GCF), in order to assess if amlodipine is present in GCF under condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021616ae0fb0215a020d34135a01f949
https://pubmed.ncbi.nlm.nih.gov/8738044
https://pubmed.ncbi.nlm.nih.gov/8738044
Autor:
Hakam F. Hadidi, Suzanne Cholerton, Sophia C. Monkman, Martin Armstrong, Yacoub M. Irshaid, Nayel M. Rawashdeh, Ann K. Daly, Jeffrey R. Idle
Publikováno v:
Pharmacogenetics. 4(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd062e4aa7cbbc7868487a6b57cc4b2
https://pubmed.ncbi.nlm.nih.gov/7920696
https://pubmed.ncbi.nlm.nih.gov/7920696
Publikováno v:
Sample Preparation for Biomedical and Environmental Analysis ISBN: 9781489913302
Heart disease is the primary cause of premature death in the western world. Calcium antagonists can be used to combat many cardiovascular diseases, including coronary vasospasm and congestive heart failure. The dihydropyridine calcium antagonists are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4679e4f640965e2295bea78a8b7ad805
https://doi.org/10.1007/978-1-4899-1328-9_14
https://doi.org/10.1007/978-1-4899-1328-9_14
Autor:
Jeffrey R. Idle, Michael D. Rawlins, Robin E Ferner, Sophia C. Monkman, C. Edwards, S. Cholerton
Publikováno v:
Scopus-Elsevier
The pharmacokinetics of nifedipine and its primary oxidised metabolite, M-I were studied in nine healthy volunteers following a single oral dose of 20 mg nifedipine alone or after pretreatment with oral co-trimoxazole. Following pretreatment with co-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb964ef0520f9c9adbce275f44a0e2cf
https://europepmc.org/articles/PMC1368311/
https://europepmc.org/articles/PMC1368311/
Publikováno v:
Scopus-Elsevier
A 57-year-old man took 30 × 20 mg nifedipine retarded release tablets. He developed hypotension, tachycardia and flushing, but remained in sinus rhythm. The concentration of nifedipine 10 h after overdose was 604 ?g 1-1, and of the M-I metabolite 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522cd371cd77bd7936a112f5195205ba
https://pubmed.ncbi.nlm.nih.gov/2261244
https://pubmed.ncbi.nlm.nih.gov/2261244
Autor:
Jeffrey R Idle, Martin Armstrong, Alan V. Boddy, Carol Boustead, Suzanne Cholerton, Jane Cooper, Ann K Daly, Janice Ellis, Wendy Gregory, Hakam Hadidi, Constance H??fer, John Holt, Julian Leathart, Nigel McCracken, Sophia C Monkman, John E. Painter, Heather Taber, Dianne Walker, Murray Yule
Publikováno v:
Scopus-Elsevier
The human body is endowed with a large number of xenobiotic chemical metabolizing enzymes, a significant proportion of which are polymorphic and thus render one individual at greater or lesser risk than another of chemically-induced disease. All exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93996da5c9d8d1a7ab720590c85451fe
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027026424&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027026424&partnerID=MN8TOARS