Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sophia B. Georghiou"'
Autor:
Sophia B. Georghiou, Margaretha de Vos, Kavindhran Velen, Paolo Miotto, Rebecca E. Colman, Daniela Maria Cirillo, Nazir Ismail, Timothy C. Rodwell, Anita Suresh, Morten Ruhwald
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTDiagnostic development must occur in parallel with drug development to ensure the longevity of new treatment compounds. Despite an increasing number of novel and repurposed anti-tuberculosis compounds and regimens, there remains a large numbe
Externí odkaz:
https://doaj.org/article/b0643a8ee9614a38b1758f391701c6ea
Autor:
Alice Brankin, Marva Seifert, Sophia B. Georghiou, Timothy M. Walker, Swapna Uplekar, Anita Suresh, Rebecca E. Colman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Universal drug susceptibility testing (DST) for tuberculosis is a major goal of the END TB strategy. PCR-based molecular diagnostic tests have been instrumental in increasing DST globally and several assays have now been endorsed by the Worl
Externí odkaz:
https://doaj.org/article/9ac86b5f954b487490cd847f293424f3
Autor:
Sophia B Georghiou, Riccardo Alagna, Daniela M Cirillo, Sergio Carmona, Morten Ruhwald, Samuel G Schumacher
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261442 (2021)
A laboratory validation study was conducted to assess the equivalence of Xpert MTB/RIF Ultra testing on the GeneXpert System and the GeneXpert Omni System ('Omni') for tuberculosis and rifampicin resistance. High concordance of the two devices was de
Externí odkaz:
https://doaj.org/article/9f45e76792b5478db72222e7ff06df09
Autor:
Priti Kambli, Kanchan Ajbani, Chaitali Nikam, Meeta Sadani, Anjali Shetty, Zarir Udwadia, Sophia B Georghiou, Timothy C Rodwell, Antonino Catanzaro, Camilla Rodrigues
Publikováno v:
International Journal of Mycobacteriology, Vol 5, Iss 1, Pp 1-6 (2016)
Objective/background: The in vitro drug-susceptibility testing of Mycobacterium tuberculosis reports isolates as resistant or susceptible on the basis of single critical concentrations. It is evident that drug resistance in M. tuberculosis is quite h
Externí odkaz:
https://doaj.org/article/5f8082566cfe40558e4b99bc78244616
Autor:
Anura David, Francesca Conradie, Nelly Ciobanu, Claudia M. Denkinger, Lesley Scott, Adam Penn-Nicholson, Valeriu Crudu, Samuel G Schumacher, Vithal Prasad Myneedu, Sophia B. Georghiou, Camilla Rodrigues, Mubin Kazi, Manpreet Bhalla, Morten Ruhwald
Publikováno v:
The Lancet Infectious Diseases. 22:242-249
Summary Background The WHO End TB Strategy requires drug susceptibility testing and treatment of all people with tuberculosis, but second-line diagnostic testing with line-probe assays needs to be done in experienced laboratories with advanced infras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42072c0a7cfa857dc15d51c5210b6a23
https://doi.org/10.1016/s1473-3099(21)00452-7
https://doi.org/10.1016/s1473-3099(21)00452-7
Autor:
Priti Kambli, Kanchan Ajbani, Chaitali Nikam, Meeta Sadani, Anjali Shetty, Zarir Udwadia, Sophia B Georghiou, Timothy C Rodwell, Antonino Catanzaro, Camilla Rodrigues
Publikováno v:
International Journal of Mycobacteriology, Vol 5, Iss 3, Pp 370-372 (2016)
Externí odkaz:
https://doaj.org/article/225953a83a524733b4f76140b885c394
Autor:
Joshua Havumaki, Doris Hillemann, Nazir Ismail, Shaheed Vally Omar, Sophia B Georghiou, Samuel G Schumacher, Catharina Boehme, Claudia M Denkinger
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173804 (2017)
INTRODUCTION:Despite recent diagnostic advances, the majority of multidrug-resistant tuberculosis (MDR-TB) cases remain undiagnosed. Line probes assays (LiPAs) hold great promise to curb the spread of MDR-TB as they can rapidly detect MDR-TB even whe
Externí odkaz:
https://doaj.org/article/e0f7104a9c424a29ac5e07a9f760d0d0
Autor:
Antonino Catanzaro, Timothy C Rodwell, Donald G Catanzaro, Richard S Garfein, Roberta L Jackson, Marva Seifert, Sophia B Georghiou, Andre Trollip, Erik Groessl, Naomi Hillery, Valeriu Crudu, Thomas C Victor, Camilla Rodrigues, Grace Shou-Yean Lin, Faramarz Valafar, Edward Desmond, Kathleen Eisenach
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136861 (2015)
The aim of this study was to compare the performance of several recently developed assays for the detection of multi- and extensively drug-resistant tuberculosis (M/XDR-TB) in a large, multinational field trial.Samples from 1,128 M/XDR-TB suspects we
Externí odkaz:
https://doaj.org/article/df2d5307077e439796b84e5699c652b5
Autor:
Miguel Santin, Claudio U. Köser, Emmanuelle Cambau, Gunnar Kahlmeter, Delia Goletti, Florian P. Maurer, Jim Werngren, Miguel Viveiros, Mateja Janković, Jakko van Ingen, Daniela Maria Cirillo, Sophia B. Georghiou, Christian G. Giske, John D. Turnidge, Thomas B. Schön, Gerard Lina
Publikováno v:
Clinical Microbiology and Infection, 26, 11, pp. 1453-1455
Clinical Microbiology and Infection, 26, 1453-1455
Clinical Microbiology and Infection, 26, 1453-1455
This is a commentary about the role of EUCAST reference method for MIC testing of the Mycobacterium tuberculosis complex?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcc9193b585579e29ac373ab98c3ca9
https://doi.org/10.1016/j.cmi.2020.07.037
https://doi.org/10.1016/j.cmi.2020.07.037
Autor:
Morten Ruhwald, Bhalla M, Myneedu Vp, Adam Penn-Nicholson, Lesley Scott, Camilla Rodrigues, Sophia B. Georghiou, Nelly Ciobanu, Anura David, Crudu, Samuel G Schumacher, Mubin Kazi, Francesca Conradie, Claudia M. Denkinger
BackgroundThe WHO End TB Strategy requires universal drug susceptibility testing and treatment of all people with tuberculosis. However, available second-line diagnostic tools are cumbersome and require sophisticated laboratory infrastructure, and ul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd765da0ebf1753ed7e18c773cb843c
https://doi.org/10.1101/2021.05.06.21256505
https://doi.org/10.1101/2021.05.06.21256505
