Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sophia B. Chernikova"'
Autor:
Lei Deng, Jason H. Stafford, Shie-Chau Liu, Sophia B. Chernikova, Milton Merchant, Lawrence Recht, J. Martin Brown
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 1, Pp 1-7 (2017)
Despite the approval of antiangiogenic therapy for glioblastoma multiforme (GBM) patients, survival benefits are still limited. One of the resistance mechanisms for antiangiogenic therapy is the induction of hypoxia and subsequent recruitment of macr
Externí odkaz:
https://doaj.org/article/9a063b90518c43ef8b06f0db5778ff48
Autor:
William R. Wilson, Larry H. Thompson, J. Martin Brown, Sophia B. Chernikova, Graham J. Atwell, Adam V. Patterson, Yongchuan Gu
PR-104 is a dinitrobenzamide mustard currently in clinical trial as a hypoxia-activated prodrug. Its major metabolite, PR-104A, is metabolized to the corresponding hydroxylamine (PR-104H) and amine (PR-104M), resulting in activation of the nitrogen m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b5326b845dbf44f19eae8363b03553
https://doi.org/10.1158/1535-7163.c.6531500
https://doi.org/10.1158/1535-7163.c.6531500
Autor:
Lawrence D. Recht, J. Martin Brown, Hannes Vogel, Donald Born, Jonathan Lavezo, Sophia B. Chernikova, Vandana Sundaram, Jaden Yang, Robyn Ball, Judith S. Pelpola, Sophie Bertrand, Scott G. Soltys, Michael Iv, Seema Nagpal, Reena P. Thomas
Purpose:Preclinical studies have demonstrated that postirradiation tumor revascularization is dependent on a stromal cell–derived factor-1 (SDF-1)/C-X-C chemokine receptor type 4 (CXCR4)-driven process in which myeloid cells are recruited from bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eac7e6786caa477fef0851e1967c49e
https://doi.org/10.1158/1078-0432.c.6528084
https://doi.org/10.1158/1078-0432.c.6528084
Autor:
Lawrence D. Recht, J. Martin Brown, Hannes Vogel, Donald Born, Jonathan Lavezo, Sophia B. Chernikova, Vandana Sundaram, Jaden Yang, Robyn Ball, Judith S. Pelpola, Sophie Bertrand, Scott G. Soltys, Michael Iv, Seema Nagpal, Reena P. Thomas
Supplementary Data from Macrophage Exclusion after Radiation Therapy (MERT): A First in Human Phase I/II Trial using a CXCR4 Inhibitor in Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636bf9d44919d0254564112cb18ff54f
https://doi.org/10.1158/1078-0432.22472016.v1
https://doi.org/10.1158/1078-0432.22472016.v1
Autor:
William R. Wilson, Larry H. Thompson, J. Martin Brown, Sophia B. Chernikova, Graham J. Atwell, Adam V. Patterson, Yongchuan Gu
Supplementary Data from Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ada6249849d71994885151e14523f66
https://doi.org/10.1158/1535-7163.22484627.v1
https://doi.org/10.1158/1535-7163.22484627.v1
Autor:
J. Martin Brown, John C. Game, Susan M. Bailey, James D. Brooks, Shirley Kwok, Diana A. Chernikova, Jennifer A. Dorth, Monica Nicolau, Brock J. Sishc, John P. Higgins, Olga V. Razorenova, Sophia B. Chernikova
PDF file - 591K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3119d0473e605dc9aca7326a8116068e
https://doi.org/10.1158/0008-5472.22393856
https://doi.org/10.1158/0008-5472.22393856
Autor:
J. Martin Brown, John C. Game, Susan M. Bailey, James D. Brooks, Shirley Kwok, Diana A. Chernikova, Jennifer A. Dorth, Monica Nicolau, Brock J. Sishc, John P. Higgins, Olga V. Razorenova, Sophia B. Chernikova
PDF file - 360K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3005c01fa9e75a33d86a992493b2f1fe
https://doi.org/10.1158/0008-5472.22393850.v1
https://doi.org/10.1158/0008-5472.22393850.v1
Autor:
J. Martin Brown, John C. Game, Susan M. Bailey, James D. Brooks, Shirley Kwok, Diana A. Chernikova, Jennifer A. Dorth, Monica Nicolau, Brock J. Sishc, John P. Higgins, Olga V. Razorenova, Sophia B. Chernikova
PDF file - 58K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d654b5d853c3cb8bffd4d90fbfccd1
https://doi.org/10.1158/0008-5472.22393853.v1
https://doi.org/10.1158/0008-5472.22393853.v1
Autor:
J. Martin Brown, John C. Game, Susan M. Bailey, James D. Brooks, Shirley Kwok, Diana A. Chernikova, Jennifer A. Dorth, Monica Nicolau, Brock J. Sishc, John P. Higgins, Olga V. Razorenova, Sophia B. Chernikova
PDF file - 61K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2494c2b664dc72c3a5cf0104ec1c6a34
https://doi.org/10.1158/0008-5472.22393847.v1
https://doi.org/10.1158/0008-5472.22393847.v1
Autor:
Bernd Jandeleit, Saman S. Ahmadian, Stephanie Andersen, Melanie Hayden Gephart, Yuelong Wang, Maxine C. Umeh-Garcia, Gordon Ringold, Wolf-Nicolas Fischer, Bryanna O. Godfrey, Jiaojiao Deng, Sophia B. Chernikova, Mirna Rodriguez, Kerry J. Koller
Publikováno v:
Mol Cancer Ther
Development of metastases to central nervous system (CNS) is an increasing clinical issue following the diagnosis of advanced breast cancer. The propensity to metastasize to CNS varies by breast cancer subtype. Of the four breast cancer subtypes, tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cd67f8bb4f38444fe13438f4100724
https://doi.org/10.1158/1535-7163.mct-21-0140
https://doi.org/10.1158/1535-7163.mct-21-0140