Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Sophia, Pfister"'
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EZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8+ T Cells
Autor: Haikuo Zhang, Shahram Salek-Ardakani, Catherine Lee, Wenjing Yang, Christopher P. Dillon, Sophia Pfister, Eleanore Hendrickson, Christopher J. Stairiker, Tao Xie, Graham D. Thomas
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Enhancer of Zeste Homolog 2 (EZH2) inhibitors (EZH2i) are approved to treat certain cancer types. Previous studies have suggested the potential to combine EZH2i with immune checkpoint blockade targeting coinhibitory receptors like PD-(L)1 and CTLA-4,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d8949c39840d92a5560137d4a2c1a0
https://doi.org/10.3389/fimmu.2021.770080
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3
Combinatorial immunotherapy induces tumor-infiltrating CD8
Autor: Natalija, Van Braeckel-Budimir, Joseph Samuel, Dolina, Jie, Wei, Xiao, Wang, Shih-Hsun, Chen, Pamela, Santiago, Guanghuan, Tu, Luca, Micci, Amir A, Al-Khami, Sophia, Pfister, Sripad, Ram, Purnima, Sundar, Graham, Thomas, Hua, Long, Wenjing, Yang, Shobha, Potluri, Shahram, Salek-Ardakani
Publikováno v: Journal for Immunotherapy of Cancer
Background Programmed death (ligand) 1 (PD-(L)1) blockade and OX40/4-1BB costimulation have been separately evaluated in the clinic to elicit potent antitumor T cell responses. The precise mechanisms underlying single agent activity are incompletely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15f5fc5632e7a7afdab5f31c58afb4a6
https://pubmed.ncbi.nlm.nih.gov/34903555
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4
Combinatorial immunotherapy induces tumor-infiltrating CD8+ T cells with distinct functional, migratory, and stem-like properties
Autor: Natalija Van Braeckel-Budimir, Joseph Samuel Dolina, Jie Wei, Xiao Wang, Shih-Hsun Chen, Pamela Santiago, Guanghuan Tu, Luca Micci, Amir A Al-Khami, Sophia Pfister, Sripad Ram, Purnima Sundar, Graham Thomas, Hua Long, Wenjing Yang, Shobha Potluri, Shahram Salek-Ardakani
Publikováno v: Journal for ImmunoTherapy of Cancer. 9:e003614
BackgroundProgrammed death (ligand) 1 (PD-(L)1) blockade and OX40/4-1BB costimulation have been separately evaluated in the clinic to elicit potent antitumor T cell responses. The precise mechanisms underlying single agent activity are incompletely u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::336eb711c3fc1f2ebfe4efe5284f692c
https://doi.org/10.1136/jitc-2021-003614
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6
Alterations of the serum N-glycan profile in female patients with Major Depressive Disorder
Autor: Valerie Vanhooren, Alexander Bürkle, Christina Boeck, Sophia Pfister, Juan Salinas-Manrique, Iris-Tatjana Kolassa, Alexander Karabatsiakis, Detlef E. Dietrich, Claude Libert
Publikováno v: Journal of affective disorders. 234
Background Glycans are short chains of saccharides linked to glycoproteins that are known to be involved in a wide range of inflammatory processes. As depression has been consistently associated with chronic low-grade inflammation, we asked whether p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113a206ba48a5c4512a40c5dfea7dfe4
https://pubmed.ncbi.nlm.nih.gov/29529546
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