Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sophia, Kelaini"'
Autor:
Koray N. Potel, Victoria A. Cornelius, Andrew Yacoub, Ali Chokr, Clare L. Donaghy, Sophia Kelaini, Magdalini Eleftheriadou, Andriana Margariti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Vascular complications are the main cause of diabetes mellitus-associated morbidity and mortality. Oxidative stress and metabolic dysfunction underly injury to the vascular endothelium and myocardium, resulting in diabetic angiopathy and cardiomyopat
Externí odkaz:
https://doaj.org/article/ce4c32075e824d97aaf0a55ac12862a1
Autor:
Chunbo Yang, Magdalini Eleftheriadou, Sophia Kelaini, Thomas Morrison, Marta Vilà González, Rachel Caines, Nicola Edwards, Andrew Yacoub, Kevin Edgar, Arya Moez, Aleksandar Ivetic, Anna Zampetaki, Lingfang Zeng, Fiona L. Wilkinson, Noemi Lois, Alan W. Stitt, David J. Grieve, Andriana Margariti
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Vascular endothelial cell (EC) dysfunction contributes to the occurrence of diabetic complications. Here the authors report that in diabetic conditions, upregulation of the RNA binding protein QKI-7 in ECs due to the imbalance of RNA splicing factors
Externí odkaz:
https://doaj.org/article/b856289dee3f46f7953a233bb72c1adc
Publikováno v:
Cells, Vol 11, Iss 16, p 2494 (2022)
Vascular diseases account for a significant number of deaths worldwide, with cardiovascular diseases remaining the leading cause of mortality. This ongoing, ever-increasing burden has made the need for an effective treatment strategy a global priorit
Externí odkaz:
https://doaj.org/article/67469125c6104f43a45837b9fda93270
Publikováno v:
Biology, Vol 10, Iss 5, p 366 (2021)
RNA-binding proteins (RBPs) are multi-faceted proteins in the regulation of RNA or its RNA splicing, localisation, stability, and translation. Amassing proof from many recent and dedicated studies reinforces the perception of RBPs exerting control th
Externí odkaz:
https://doaj.org/article/4c5f081484294de1bb122113d24e8347
Autor:
Chunbo Yang, Magdalini Eleftheriadou, Sophia Kelaini, Thomas Morrison, Marta Vilà González, Rachel Caines, Nicola Edwards, Andrew Yacoub, Kevin Edgar, Arya Moez, Aleksandar Ivetic, Anna Zampetaki, Lingfang Zeng, Fiona L. Wilkinson, Noemi Lois, Alan W. Stitt, David J. Grieve, Andriana Margariti
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/0052053883264ab39db9bf4a7efba1c7
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Diabetes is one of the major health care problems worldwide leading to huge suffering and burden to patients and society. Diabetes is also considered as a cardiovascular disorder because of the correlation between diabetes and an increased incidence
Externí odkaz:
https://doaj.org/article/5770be94ae4d45c4ae9cc6c3be06dfad
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Cardiovascular disease (CVD), despite the advances of the medical field, remains one of the leading causes of mortality worldwide. Discovering novel treatments based on cell therapy or drugs is critical, and induced pluripotent stem cells (iPS Cells)
Externí odkaz:
https://doaj.org/article/2fcd02ea972d448f9883f88ee7f870eb
Autor:
Hojjat Naderi-Meshkin, Magdalini Eleftheriadou, Garrett Carney, Victoria A Cornelius, Clare-Ann Nelson, Sophia Kelaini, Andrew Yacoub, Clare Donaghy, Philip D Dunne, Raheleh Amirkhah, Anna Zampetaki, Lingfang Zeng, Alan W Stitt, David J Grieve, Andriana Margariti
The presence of both endothelial cells (ECs) and mural cells are central to the proper function of blood vessels in health and pathological changes in diseases including diabetes. Although iPSCs-derived vascular organoids (VOs) provide an appealing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::298b4714cf403971085a96a8fee69520
https://doi.org/10.1101/2022.07.18.500478
https://doi.org/10.1101/2022.07.18.500478
Autor:
Victoria A. Cornelius, Martha Gonzalez, Garret Carney, Andriana Margariti, Sophia Kelaini, Hojjat Naderi Meskin, Guillermo Lopez Campos, Alan W. Stitt, Thomas Morrison, Andrew Yacoub, Chunbo Yang, Noemi Lois, David J. Grieve, Magdalini Eleftheriadou
Publikováno v:
ACHD/Valve disease/Pericardial disease/Cardiomyopathy.
Diabetic endotheliopathy is the main cause for impaired angiogenesis and reduced neovascularization that lead to microvascular injury and vascular complications. The pathogenic basis for vascular complications arising from diabetes is complex. Elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c0acc1cbaac7e9366d9cddfe26b5e4f
https://doi.org/10.1136/heartjnl-2021-bcs.9
https://doi.org/10.1136/heartjnl-2021-bcs.9
Publikováno v:
Biology, Vol 10, Iss 366, p 366 (2021)
Kelaini, S, Chan, C, Cornelius, V & Margariti, A 2021, ' RNA-Binding Proteins Hold Key Roles in Function, Dysfunction, and Disease ', Biology . https://doi.org/10.3390/biology10050366
Biology
Kelaini, S, Chan, C, Cornelius, V & Margariti, A 2021, ' RNA-Binding Proteins Hold Key Roles in Function, Dysfunction, and Disease ', Biology . https://doi.org/10.3390/biology10050366
Biology
Simple Summary Chronic hyperglycemia manifests in a variety of different micro- and macrovascular disorders such as diabetes mellitus and cardiovascular disease and has been shown to have links to post-transcriptional dysregulation. Equally, the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1444a91c903b184f2d41b913edb49f
https://www.mdpi.com/2079-7737/10/5/366
https://www.mdpi.com/2079-7737/10/5/366