The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB.

Autor: Losby M; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Hayes M; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Valfort A; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Sopariwala DH; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Sanders R; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Walker JK; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Xu W; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Narkar VA; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Zhang L; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Billon C; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.)., Burris TP; Division of Biology & Biomedical Sciences, Washington University School of Medicine, St. Louis (M.L.); Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, Florida (M.H., A.V., R.S., T.P.B.); University of Florida Genetics Institute, Gainesville, Florida (T.P.B.); Brown Foundation Institute of Molecular Medicine, McGovern Medical School, UTHealth, Houston, Texas, (D.H.S., V.A.N.); Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri (J.K.W.); Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX (W.X., L.Z.); and Center for Clinical Pharmacology, St Louis College of Pharmacy, University of Health Sciences and Pharmacy, St. Louis MO (C.B.) Burris.thomas@ufl.edu.

Publikováno v: Molecular pharmacology [Mol Pharmacol] 2024 Sep 17; Vol. 106 (4), pp. 164-172. Date of Electronic Publication: 2024 Sep 17.

Innately expressed estrogen-related receptors in the skeletal muscle are indispensable for exercise fitness.

Autor: Sopariwala DH; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA., Rios AS; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA., Pei G; Center for Precision Medicine, School of Biomedical Informatics, The University of Texas Health Science Center, Houston, Texas, USA., Roy A; Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA., Tomaz da Silva M; Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA., Thi Thu Nguyen H; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA., Saley A; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA.; Department of Biosciences, Rice University, Houston, Texas, USA., Van Drunen R; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA., Kralli A; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Mahan K; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA.; Department of Integrative Biology and Pharmacology, The University of Texas Health Science Center, Houston, Texas, USA., Zhao Z; Center for Precision Medicine, School of Biomedical Informatics, The University of Texas Health Science Center, Houston, Texas, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center, Houston, Texas, USA., Kumar A; Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA., Narkar VA; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas, USA.; Graduate School of Biomedical Sciences at UTHealth, Houston, Texas, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 Feb; Vol. 37 (2), pp. e22727.

Estrogen-related receptor alpha is an AMPK-regulated factor that promotes ischemic muscle revascularization and recovery in diet-induced obese mice.

Autor: Sopariwala DH; Center for Metabolic & Degenerative Diseases Institute of Molecular Medicine, UTHealth McGovern Medical School Houston Texas USA., Rios AS; Center for Metabolic & Degenerative Diseases Institute of Molecular Medicine, UTHealth McGovern Medical School Houston Texas USA., Park MK; Department of Molecular and Cellular Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA., Song MS; Department of Molecular and Cellular Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA., Kumar A; Department of Pharmacological and Pharmaceutical Sciences College of Pharmacy, University of Houston Houston Texas USA., Narkar VA; Center for Metabolic & Degenerative Diseases Institute of Molecular Medicine, UTHealth McGovern Medical School Houston Texas USA.

Publikováno v: FASEB bioAdvances [FASEB Bioadv] 2022 Jun 22; Vol. 4 (9), pp. 602-618. Date of Electronic Publication: 2022 Jun 22 (Print Publication: 2022).

Is Upregulation of Sarcolipin Beneficial or Detrimental to Muscle Function?

Autor: Bal NC; School of Biotechnology, KIIT University, Bhubaneswar, India., Gupta SC; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States.; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, India., Pant M; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States., Sopariwala DH; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States., Gonzalez-Escobedo G; Departments of Microbiology and Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States., Turner J; Departments of Microbiology and Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.; Texas Biomedical Research Institute, San Antonio, TX, United States., Gunn JS; Departments of Microbiology and Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.; Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States., Pierson CR; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, United States.; Department of Pathology, The Ohio State University, Columbus, OH, United States.; Department of Biomedical Education and Anatomy, The Ohio State University, Columbus, OH, United States., Harper SQ; Department of Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, United States., Rafael-Fortney JA; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States., Periasamy M; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States.; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, United States.

Publikováno v: Frontiers in physiology [Front Physiol] 2021 Mar 01; Vol. 12, pp. 633058. Date of Electronic Publication: 2021 Mar 01 (Print Publication: 2021).

Loss of Estrogen-Related Receptor Alpha Facilitates Angiogenesis in Endothelial Cells.

Autor: Likhite N; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA., Yadav V; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA., Milliman EJ; BERG LLC, Framingham, Massachusetts, USA., Sopariwala DH; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA., Lorca S; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA., Narayana NP; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA., Sheth M; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA.; Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, USA., Reineke EL; Center for Bioenergetics, Houston Methodist Research Institute, Houston, Texas, USA., Giguère V; Department of Biochemistry, Medicine and Oncology, Faculty of Medicine, Goodman Cancer Research Centre, McGill University, Montreal, Canada., Narkar V; Metabolic and Degenerative Diseases, Institute of Molecular Medicine, The University of Texas McGovern Medical School, Houston, Texas, USA Vihang.a.narkar@uth.tmc.edu.; Integrative Biology and Pharmacology, The University of Texas McGovern Medical School, Houston, Texas, USA.; Graduate School of Biomedical Sciences at The University of Texas Health Science Center, Houston, Texas, USA.

Publikováno v: Molecular and cellular biology [Mol Cell Biol] 2019 Feb 15; Vol. 39 (5). Date of Electronic Publication: 2019 Feb 15 (Print Publication: 2019).