Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Sooyeon Song"'
Autor:
Laura Fernández-García, Xinyu Gao, Joy Kirigo, Sooyeon Song, Michael E. Battisti, Rodolfo Garcia-Contreras, Maria Tomas, Yunxue Guo, Xiaoxue Wang, Thomas K. Wood
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTAlthough toxin/antitoxin (TA) systems are ubiquitous, beyond phage inhibition and mobile element stabilization, their role in host metabolism is obscure. One of the best-characterized TA systems is MqsR/MqsA of Escherichia coli, which has bee
Externí odkaz:
https://doaj.org/article/ec684c2071ab40e3ad374da547202c9f
Autor:
Laura Fernández-García, Sooyeon Song, Joy Kirigo, Michael E. Battisti, Maiken E. Petersen, María Tomás, Thomas K. Wood
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Myriad bacterial anti-phage systems have been described and often the mechanism of programmed cell death is invoked for phage inhibition. However, there is little evidence of “suicide” under physiological conditions for these systems. In
Externí odkaz:
https://doaj.org/article/0101b5ea5fb0489ca3d8433f9581704c
Autor:
Thomas K. Wood, Sooyeon Song
Publikováno v:
Biofilm, Vol 2, Iss , Pp 100018- (2020)
Procaryotes starve and face myriad stresses. The bulk population actively resists the stress, but a small population weathers the stress by entering a resting stage known as persistence. No mutations occur, and so persisters behave like wild-type cel
Externí odkaz:
https://doaj.org/article/00ba8f2b407944a796eb3a1aae6f66ae
Autor:
Sooyeon Song, Thomas K. Wood
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Toxin/antitoxin (TA) systems are present in most prokaryote genomes. Toxins are almost exclusively proteins that reduce metabolism (but do not cause cell death), and antitoxins are either RNA or proteins that counteract the toxin or the RNA that enco
Externí odkaz:
https://doaj.org/article/353c0dedebcb425c960c1c0cfd2c1b48
Autor:
Sooyeon Song, Thomas K. Wood
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Given that a subpopulation of most bacterial cells becomes dormant due to stress, and that the resting cells of pathogens can revive and reconstitute infections, it is imperative to find methods to treat dormant cells to eradicate infections. The dor
Externí odkaz:
https://doaj.org/article/148f419d71f44123be31f157fab4d43e
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: Persistence, the stress-tolerant state, is arguably the most vital phenotype since nearly all cells experience nutrient stress, which causes a sub-population to become dormant. However, how persister cells wake to reconstitute infections is
Externí odkaz:
https://doaj.org/article/fe20a2eb3145415982324626ebb893f9
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 737-749.e4 (2019)
Summary: Cells are social, and self-recognition is a conserved aspect of group behavior where cells assist kin and antagonize non-kin. However, the role of phage in self-recognition is unexplored. Here we find that a demarcation line is formed betwee
Externí odkaz:
https://doaj.org/article/f3daceef3c764365ab0dc303d6f4692b
Autor:
Sooyeon Song, Thomas K. Wood
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 386 (2021)
Autoinducer 2 (AI-2) is a ubiquitous metabolite but, instead of acting as a “universal signal,” relatively few phenotypes have been associated with it, and many scientists believe AI-2 is often a metabolic byproduct rather than a signal. Here, th
Externí odkaz:
https://doaj.org/article/55ea7fedd9be4854bc51aed6a7b3e829
Autor:
Sooyeon Song, Thomas K. Wood
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/86d43e6c780742dd8dbc5bf89d74e301
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Pseudomonas aeruginosa causes many biofilm infections, and the rugose small-colony variants (RSCVs) of this bacterium are important for infection. We found here that inactivation of PA2444, which we determined to be a serine hydroxymethyltransferase
Externí odkaz:
https://doaj.org/article/cab3923edacf40bd8a5d7627793e5e7f